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HESI A2 A&P (Anatomy & Physiology) | Practice Questions with Answers and Rationales Study Guide

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Prepare confidently for your HESI A2 Exam with this comprehensive Anatomy & Physiology (A&P) study guide designed to help nursing applicants master essential human body concepts. This resource includes carefully selected practice questions, correct answers, and detailed rationales covering key topics such as body systems, organ functions, cellular processes, and physiological regulation. Ideal for structured study and last-minute revision, it strengthens understanding, improves test performance, and builds confidence for success on your HESI A2 entrance exam.

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HESI A2 A&P (Anatomy &
Physiology) | Practice
Questions with Answers
and Rationales Study Guide
| Graded A+ | Guaranteed
Success



Updated 2026 Questions and Answers

100% Verified Exam Prep and Comprehensive Rationales
Included

,Which is an anterior muscle? B. An anterior muscle is located near the front of the body. Of those listed, the
A. Gluteus maximus quadriceps( frontal thigh muscle) is the most anterior.
B. Quadriceps femoris
C. Biceps femoris
D. Adductor magnus


How might the headrest on a car prevent traumatic B. The headrest prevents the head from moving too far backward, or
injury? hyperextending the neck beyond its normal range.
A. By limiting hyperflexion of the neck
B. By limiting hyperextension of the neck
C. By reducing vertebral compression
D. By preventing disc degeneration


Which might you expect to see in a whiplash injury? D. Because of the hyperflexion and hyperextension caused by such a collision, it
A. Cardiopulmonary problems is not uncommon to find tears or stretching of the ligaments of the spine. The
B. Side-to-side spinal curvature injury is front-to-back, making choice B unlikely, and a herniated disc (choice C) is
C. Eventual herniation of discs more of a compression injury.
D. Traumatic injury to ligaments

, Muscle contractions that normally move food along the C. Defecation(choice A) is the elimination of waste. Osmosis (choice B) is the
human digestive system are known as ________. movement of molecules across a membrane. Circulation (choice D) is the
A. defecation movement of blood through the body. Peristalsis (choice C) is the involuntary,
B. osmosis wavelike movement of muscles in the intestine and elsewhere that pushes food
C. peristalsis along.
D. circulation


Which type of nutrient does not provide the body with A. Some nutrients supply energy, and others support metabolism. Nutrients in the
energy? first set include carbohydrates, proteins, and fats. Those in the secound set
A. Vitamin include vitamins, minerals, and water.
B. Carbohydrate
C. Fat
D. Protein


Where would you be likely to find a Schwann cell? B. Schwann cells wrap around the nerve fibers and form the myelin sheath in the
A. In the digestive system peripheral nervous system.
B. In the nervous system
C. In the skeletal system
D. In the muscular system


How does the nervous system work with the muscular B. The nervous system is made up of the brain, spinal cord, and nerves. It receives
system? and transmits signals from the environment that regulate voluntary and involuntary
A. The muscles of the body produce chemicals that feed movement.
the nerves.
B. The nervous system tells the muscles how to respond
to the environment.
C. The nervous system releases chemicals that remove
excess waste from the muscles.
D. The muscular system provides input that allows the
nerves to make decisions.


Which part of the nervous system includes the femoral , A. The symphathetic and parasympathetic systems (choice C and D) are part of
radial, and ulnar nerves? the autonomic nervous system (choice B), which controls involuntary actions of
A. Somatic the smooth muscles, glands, and heart. The somatic nervous system (choice A) has
B. Autonomic to do with reception of external stimuli and voluntary control of the muscles.
C. Sympathetic
D. Parasympathetic


Where might a herniated lumbar disc be most likely to C. Damage to a disc in the lower back will most likely cause pain radiating
create pain? downward along the sciatic nerve.
A. Along the radial nerve
B. Within the spinal cord
C. Along the sciatic nerve
D. Along the tibial nerve


What is the name of the bone in the human thigh? B. The ulna (choice A), radius (choice C), and humerus (choice D) are arm bones.
A. Ulna
B. Femur
C. Radius
D. Humerus

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