AAMC FREE FULL LENGTH EXAM B/B |LATEST UPLOAD |GRADED
A+
The association observed experimentally between the expression of miRNAs and mRNAs in
AR kidney transplants indicates that miRNAs regulate the expression of genes implicated in
which type(s) of immune response(s)?
A.
Adaptive immunity only
B.
Humoral immunity only
C.
Innate and cell-mediated immunity only
D.
Adaptive and innate immunity only - correct answer-Answer A
The passage quotes "levels of CD3 (T cell) mRNA and CD20 (B cell) mRNA and determined
that there was a positive correlation between these mRNA levels and the levels of miR-142-
5p, miR-155, and miR-223 but not with miR-10b, miR-30a-3p and let-7c" which indicates T
cells and B cells, which are only present in the adaptive immunity.
Based on Figure 1, which patient is LEAST likely to benefit from therapy with
immunosuppressors?
A patient whose transplanted kidneys are associated with miRNA expression patterns
characterized by:
A.
high levels of miR-155
B.
low levels of let-7c.
C.
high levels of miR-30a-3p.
D.
low levels of miR-10b. - correct answer-Answer C
Using the graph, we are trying to look for the miRNA which has the highest
The arrow in the graph indicates the curve representing the melting temperature for which
miRNA, assuming 100% base complementarity with its target sequence?
A.
miR-142-5p
, B.
miR-223
C.
miR-10b
D.
miR-30a-3p - correct answer-Answer D
Look for highest GC content. The graph is shifted right, so this means the boiling point is
elevated.
Individual nucleotides within the backbone of the regulatory RNAs discussed in the
passage are held together by:
A.
disulfide bridges.
B.
phosphodiester linkages.
C.
hydrogen bonds.
D.
glycosidic linkages. - correct answer-Answer B
A. hold together cysteine molecules in amino acid peptide chains
B. hold together nucleotides
C. Hold together individual nitrogenous bases in DNA
D. Hold carb molecules together
From Table 1, which bacteria can use galactose as an energy source?
A.
Ruminococcus
B.
Faecalibacterium
C.
Odoribacter
D.
Phascolactobacterium - correct answer-Answer C
Glucose + isomers = galactose and fructose
A+
The association observed experimentally between the expression of miRNAs and mRNAs in
AR kidney transplants indicates that miRNAs regulate the expression of genes implicated in
which type(s) of immune response(s)?
A.
Adaptive immunity only
B.
Humoral immunity only
C.
Innate and cell-mediated immunity only
D.
Adaptive and innate immunity only - correct answer-Answer A
The passage quotes "levels of CD3 (T cell) mRNA and CD20 (B cell) mRNA and determined
that there was a positive correlation between these mRNA levels and the levels of miR-142-
5p, miR-155, and miR-223 but not with miR-10b, miR-30a-3p and let-7c" which indicates T
cells and B cells, which are only present in the adaptive immunity.
Based on Figure 1, which patient is LEAST likely to benefit from therapy with
immunosuppressors?
A patient whose transplanted kidneys are associated with miRNA expression patterns
characterized by:
A.
high levels of miR-155
B.
low levels of let-7c.
C.
high levels of miR-30a-3p.
D.
low levels of miR-10b. - correct answer-Answer C
Using the graph, we are trying to look for the miRNA which has the highest
The arrow in the graph indicates the curve representing the melting temperature for which
miRNA, assuming 100% base complementarity with its target sequence?
A.
miR-142-5p
, B.
miR-223
C.
miR-10b
D.
miR-30a-3p - correct answer-Answer D
Look for highest GC content. The graph is shifted right, so this means the boiling point is
elevated.
Individual nucleotides within the backbone of the regulatory RNAs discussed in the
passage are held together by:
A.
disulfide bridges.
B.
phosphodiester linkages.
C.
hydrogen bonds.
D.
glycosidic linkages. - correct answer-Answer B
A. hold together cysteine molecules in amino acid peptide chains
B. hold together nucleotides
C. Hold together individual nitrogenous bases in DNA
D. Hold carb molecules together
From Table 1, which bacteria can use galactose as an energy source?
A.
Ruminococcus
B.
Faecalibacterium
C.
Odoribacter
D.
Phascolactobacterium - correct answer-Answer C
Glucose + isomers = galactose and fructose
