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1. Bioavailability: the rate at and the extent to which a nutrient is absorbed and used
2. Absorption: movement of a drug from its site of administration into the bloodstream for distribution to the
tissues
3. Distribution: transport of a drug by the bloodstream to its site of action
4. Another word for metabolism?: biotransformation
5. Where does biotransformation occur?: Mainly occurs in the liver
6. Biotransformation (metabolism): - One or more biochemical reactions involving a parent drug
7. What does biotransformation produce?: - metabolite that can be inactive or active
8. Excretion: elimination of drugs from the body
9. Half-Life: time required for one-half (50%) of a given drug to be removed from the body
10. Why can't extended release or enteric coated (EC) oral medications be
crushed: - it could accelerate the release of the drug from the dosage form and possibly cause toxicity
11. What are the common drugs that are considered first pass drugs?: - Oral
- NG tubes
- PEG tubes
12. What is the fastest enteral route for absorption?: - Buccal / Sublingual tabs
13. What is the slowest enteral route for absorption?: - enteric coated tablets
14. What is the order of fastest to slowest enteral routes for absorption (list is in
descended order)?: - Buccal/ Sublingual
- Liquid, Elixirs, syrups
- Tablets
- Enteric coated tablet
15. What enteral route absorption is faster? Liquids, elixirs, syrups or tablets?: -
Liquids, elixirs, syrups
16. What is enteral route absorption is faster? Tablets or Enteric coated tablets-
: Tablets
17. What is the order of fastest to slowest parenteral routes for absorption? (list
is in descending order)?: - IV
- IM
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- SQ
18. What parenteral route is the fastest absorption?: - IV
19. What parenteral route is the slowest absorption rate?: - SubQ
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