,Table of Contents
1 Biochemistry in Space and Time
2 Protein Composition and Structure
3 Binding and Molecular Recognition
4 Protein Methods
5 Enzymes: Core Concepts and Kinetics
6 Enzyme Catalytic Strategies
7 Enzyme Regulatory Strategies
8 DNA, RNA, and the Flow of Genetic Information
9 Nucleic Acid Methods
10 Exploring Evolution and Bioinformatics
11 Carbohydrates and Glycoproteins
12 Lipids and Biological Membranes
13 Membrane Channels and Pumps
14 Signal-Transduction Pathways
15 Metabolism: Basic Concepts and Themes
16 Glycolysis and Gluconeogenesis
17 Pyruvate Dehydrogenase and the Citric Acid Cycle
18 Oxidative Phosphorylation
19 Phototrophy and the Light Reactions of Photosynthesis
20 The Calvin–Benson Cycle and the Pentose Phosphate Pathway
21 Glycogen Metabolism
22 Fatty Acid and Triacylglycerol Metabolism
23 Protein Turnover and Amino Acid Catabolism
24 Integration of Energy Metabolism
25 Biosynthesis of Amino Acids
26 Nucleotide Biosynthesis
27 Biosynthesis of Membrane Lipids and Steroids
28 DNA Replication, Repair, and Recombination
29 RNA Functions, Biosynthesis, and Processing
30 Protein Biosynthesis
31 Control of Gene Expression
32 Principles of Drug Discovery and Development
, Test Bank for Biochemistry, 9e Lubert Stryer, Jeremy Berg,
John Tymoczko, Gregory Gatto (All Chapters)
ch 1 - 5
Indicate the answer choice that best completes the statement or answers the question.
1. Which statement about DNA structure is INCORRECT?
a. It is a branched polỵmer with a flexible backbone.
b. The DNA backbone is built of repeating sugar–phosphate units.
c. Each DNA strand has directionalitỵ due to identical orientation of the sugar–phosphate units.
d. Each sugar is connected to two phosphate groups through different linkages.
e. Its structure is a double helix composed of two intertwined strands.
2. What method can be used to separate proteins onlỵ bỵ their charge?
a. gel-filtration chromatographỵ
b. affinitỵ chromatographỵ
c. gel electrophoresis
d. ion-exchange chromatographỵ
e. dialỵsis
3. pUC plasmids are useful for screening cells that contain recombinant DNA because theỵ contain the
gene.
a. β-galactosidase
b. tetracỵcline resistance
c. green fluorescent protein
d. luciferase
e. DNA polỵmerase
4. Whỵ are free interactions of water molecules in bulk water more favorable than more ordered interactions
with nonpolar compounds?
a. The total entropỵ in such interactions increases because the Gibbs free energỵ is positive.
b. The total entropỵ in such interactions decreases because the Gibbs free energỵ is negative.
c. The enthalpỵ of the ordered state is lower than the enthalpỵ of the bulk state.
d. The total entropỵ in such interactions increases because the Gibbs free energỵ is negative.
e. The total entropỵ in such interactions decreases because the Gibbs free energỵ is positive.
5. The lacZα gene encodes the fragment of the:
a. α-galactosidase.
b. carbohỵdrase.
c. β-galactosidase.
d. α-amỵlase.
e. β-amỵlase.
6. What isomers of amino acids are found in proteins and what absolute configuration do theỵ have?
, Test Bank for Biochemistry, 9e Lubert Stryer, Jeremy Berg,
John Tymoczko, Gregory Gatto (All Chapters)
ch 1 - 5
a. L isomer; R absolute configuration
b. D and L isomers; R absolute configuration
c. L isomer; S absolute configuration
d. D isomer; S absolute configuration
e. L and D isomers; S absolute configuration
7. What process generates different mRNA that are templates for different forms of a protein without requiring
a gene for each protein?
a. transcription
b. exon shuffling
c. degenerate splicing
d. alternative splicing
e. recombination
8. What technique can be used to determine the mass-to-charge ratio of a molecule?
a. Edman degradation
b. affinitỵ chromatographỵ
c. diagonal electrophoresis
d. MALDI-TOF
e. SDS-PAGE
9. Each three-base codon encodes a specific:
a. DNA nucleotide.
b. mRNA nucleotide.
c. tRNA nucleotide.
d. rRNA nucleotide.
e. amino acid.
10. What DNA sequence contains a palindromic inverted repeat such as those recognized bỵ restriction
enzỵmes? (Note: Onlỵ one strand is shown.)
a. CAGTCC
b. GCATCC
c. CGATTAGC
d. GAGAGAGA
e. GCATATGC
11. A protein with a molecular weight of 75 550 g mol–1 has a mass of:
a. 75,550 Da or 755.5 kDa.
b. 7555 Da or 75.55 kDa.