Review Notes for Advanced Patho Exam 3 Summer 2020

Hematological Alterations Know lab values for a person with anemia* What hemoglobin is concerning or indicates anemia? Less than 12 for men and less than 15 for women. Erythrocytes (red blood cells [RBCs]) An RBC is a small disk with two unique properties: (1) a biconcave shape and (2) the capacity to be reversibly deformed. • Responsible for oxygenation-the shape allows for optimal gas exchange • Average lifespan of an erythrocyte- 120 days Hemoglobin synthesis: very dependent on nutritional intake. IRON (Male: 16g/dl; female: 14g/dl)Aplastic Anemia a critical condition in most cases being caused by an autoimmune disease against hematopoiesis by activated cytotoxic T cells. It is characterized by pancytopenia, a reduction or absence of all three blood cell types, resulting from failure or suppression of bone marrow to produce adequate amounts of erythrocytes, leukocytes, and thrombocytes blood cells.Review Notes for Advanced Patho Exam 3 Summer 2020 Hematological Alterations Know lab values for a person with anemia* What hemoglobin is concerning or indicates anemia? Less than 12 for meHematological Alterations Know lab values for a person with anemia* What hemoglobin is concerning or indicates anemia? Less than 12 for men and less than 15 for women. Erythrocytes (red blood cells [RBCs]) An RBC is a small disk with two unique properties: (1) a biconcave shape and (2) the capacity to be reversibly deformed. • Responsible for oxygenation-the shape allows for optimal gas exchange • Average lifespan of an erythrocyte- 120 days Hemoglobin synthesis: very dependent on nutritional intake. IRON (Male: 16g/dl; female: 14g/dl)Aplastic Anemia a critical condition in most cases being caused by an autoimmune disease against hematopoiesis by activated cytotoxic T cells. It is characterized by pancytopenia, a reduction or absence of all three blood cell types, resulting from failure or suppression of bone marrow to produce adequate amounts of erythrocytes, leukocytes, and thrombocytes blood cells.Review Notes for Advanced Patho Exam 3 Summer 2020 Hematological Alterations Know lab values for a person with anemia* What hemoglobin is concerning or indicates anemia? Less than 12 for me