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Evolve HESI Pharmacology Practice – Nursing Exam Review Questions

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This document includes HESI pharmacology practice questions from Evolve resources. It focuses on drug safety, mechanisms, and clinical application for nursing exams.

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Evolve Pharmacology hesi practice



A client who has been taking C) Have you had any relief from urinary pain, burning, or
phenazopyridine (Pyridium) for symptoms of urgency?
urethritis and cystitis comes to the clinic Feedback:
because her urine is reddish-orange. Which Phenazopyridine, an over-the-counter urinary analgesic, acts
question should the practical nurse ask to on the mucosa of the urinary tract to relieve urinary pain,
determine if the medication has been burning, itching, or urgency (C) associated with urethritis and
effective? cystitis. Although determining if the client is forcing fluids (A),
A) How much water have you been drinking experiencing staining from Pyridium's side effect (B), or having
each day? signs of a urinary infection (D) are worthwhile assessments, the
B) Does the urine color stain your toilet therapeutic response of Pyridium is related to urinary
bowl or undergarments? discomforts only.
C) Have you had any relief from urinary
pain, burning, or urgency?
D) Did your urine appear cloudy or have a
foul odor on voiding?




4/16/2026, 12:59:57 PM

,Evolve Pharmacology hesi practice


A male client who has been receiving an D) Shave with an electric razor.
antineoplastic drug has developed Feedback:
thrombocytopenia. What instructions should Thrombocytopenia is a common side effect of bone marrow
the practical nurse (PN) reinforce? depression caused by several antineoplastic agents. The client
A) Use suppository form of drugs. is experiencing a low platelet count and should use an
B) Avoid large public gatherings. electric razor (D) to reduce his risk of bleeding. (A, B, and C)
C) Rise slowly when standing up. are not indicated for a client who needs to implement
D) Shave with an electric razor. thrombocytopenia precautions.


The practical nurse (PN) is caring for a client B) Weight gain.
who has been taking prednisone Feedback:
(Deltasone) daily for a year. Which adverse Long term use of prednisone causes fluid retention and
effect should the PN document in the redistribution of fat deposition. Weight gain (B) and moon face
client's record? reflect adverse effects of long-term prednisone use and
A) Photosensitvity. should be documented. (A, C, and D) do not occur with
B) Weight gain. treatment using prednisone.
C) Loss of hair.
D) Pale skin color.




4/16/2026, 12:59:57 PM

,Evolve Pharmacology hesi practice


A female client with recurring headaches B) Hepatic enzymes.
tells the practical nurse (PN) that she has Feedback:
been taking at least 4 grams of Liver toxicity can occur when doses of acetaminophen
acetaminophen a day. Which laboratory exceed 4 grams a day, resulting in an elevation in hepatic
studies should the PN review for this client? enzyme values (B). (A, C, and D) do not reveal findings related
A) Creatinine clearance. to acetaminophen toxicity.
B) Hepatic enzymes.
C) Coagulation values.
D) Arterial blood gases.


A client receives a prescription for an oral A) Constipation.
opioid analgesic for post-operative pain. Feedback:
Which adverse effect should the practical Opioid analgesics slow peristalsis, which leads to constipation
nurse (PN) monitor for with the client? (A), a common side effect of opiates. (B, C, and D) are not
A) Constipation. associated with opioid analgesics.
B) Photosensitivity.
C) Decreased heart rate.
D) Frequent urination.




4/16/2026, 12:59:57 PM

, Evolve Pharmacology hesi practice


Which action should the practical nurse D) Place the medication between the upper molar teeth and
implement when administering a buccal cheek.
medication? Feedback:
A) Encourage the client to swallow. Buccal medications are placed between the upper molar
B) Administer water with medication. teeth and the cheek (D) for absorption by the capillaries of
C) Ensure the medication is positioned the oral mucosa. The client should be cautioned against
under the tongue. swallowing, not (A). Buccal medications are not administered
D) Place the medication between the upper with water (B). (C) describes sublingual administration.
molar teeth and cheek.




4/16/2026, 12:59:57 PM

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