Med_Surg Pharmacology - Exam 1_ Medications
Cytoxan (Cyclophosphamide) Antineoplastics, immunosuppressants, Alkylating Agen
Pharmacologic:alkylating agents
Pregnancy Category D
t
________ is used in chemotherapy to kill rapidly dividing cells,
such as cancer cells and immune system cells.
Hemorrhagic cystitis and Darkening of the fingernails and skin
is a common adverse effect
Asses for other med use, schedule, etc
Need to report sore throat or slight fever due to impaired
immune system while on drugs
Use soft toothbrush, take med in the morning so the body can
excrete it during the day, avoid animal fat
Nitrogen mustard (Mustargen) ( Alkylating Agent
mechlorethamine HCL)
4/16/2026, 12:59:57 PM
,Med_Surg Pharmacology - Exam 1_ Medications
doxorubicin (Adriamycin) Anthracycline chemo drug
antitumor antibiotic
Cardiotoxicity is a known adverse effect of this drug and is
manifested in shortness of breath, edema, and palpitations.
Urine color changes occur
Side effects: alopecia, nausea, vomiting, stomatitis,
myelosuppression (watch for anemia)
Adverse reactions: vesication (except for bleomycin and
mithracin) blistering of tissues (report right away after
stopping infusion).
Cultural considerations - neutropenia (Asians),
hyperpigmentation for darker skin. Put on reverse isolation.
4/16/2026, 12:59:57 PM
, Med_Surg Pharmacology - Exam 1_ Medications
Blenoxane (bleomycin) Antineoplastic Agent - chemo drug
Antitumor Antibiotics
Intercalacting agent blocking topoisomerase II, SE: pulmonary
rxns most common pneumonia, hypersensitivy rxns, max
lifetime dose 400 units
Bleomycin can cause anaphylaxis, so patients should be
monitored for respiratory distress
vincristine (Oncovin) Antineoplastic
A plant alkaloid chemotherapeutic agent
Uses: Hodgkin's disease, Leukemias, Neuroblastoma,
Malignant lymphomas, Rhabdomyosarcoma, Wilms' tumor,
Other tumors.
Common Side effect: Peripheral neuropathy can occur with
this drug and is manifested by difficulty walking and numbness
and tingling in the fingers and toes. will cause permanent
damage if not treated.
4/16/2026, 12:59:57 PM
Cytoxan (Cyclophosphamide) Antineoplastics, immunosuppressants, Alkylating Agen
Pharmacologic:alkylating agents
Pregnancy Category D
t
________ is used in chemotherapy to kill rapidly dividing cells,
such as cancer cells and immune system cells.
Hemorrhagic cystitis and Darkening of the fingernails and skin
is a common adverse effect
Asses for other med use, schedule, etc
Need to report sore throat or slight fever due to impaired
immune system while on drugs
Use soft toothbrush, take med in the morning so the body can
excrete it during the day, avoid animal fat
Nitrogen mustard (Mustargen) ( Alkylating Agent
mechlorethamine HCL)
4/16/2026, 12:59:57 PM
,Med_Surg Pharmacology - Exam 1_ Medications
doxorubicin (Adriamycin) Anthracycline chemo drug
antitumor antibiotic
Cardiotoxicity is a known adverse effect of this drug and is
manifested in shortness of breath, edema, and palpitations.
Urine color changes occur
Side effects: alopecia, nausea, vomiting, stomatitis,
myelosuppression (watch for anemia)
Adverse reactions: vesication (except for bleomycin and
mithracin) blistering of tissues (report right away after
stopping infusion).
Cultural considerations - neutropenia (Asians),
hyperpigmentation for darker skin. Put on reverse isolation.
4/16/2026, 12:59:57 PM
, Med_Surg Pharmacology - Exam 1_ Medications
Blenoxane (bleomycin) Antineoplastic Agent - chemo drug
Antitumor Antibiotics
Intercalacting agent blocking topoisomerase II, SE: pulmonary
rxns most common pneumonia, hypersensitivy rxns, max
lifetime dose 400 units
Bleomycin can cause anaphylaxis, so patients should be
monitored for respiratory distress
vincristine (Oncovin) Antineoplastic
A plant alkaloid chemotherapeutic agent
Uses: Hodgkin's disease, Leukemias, Neuroblastoma,
Malignant lymphomas, Rhabdomyosarcoma, Wilms' tumor,
Other tumors.
Common Side effect: Peripheral neuropathy can occur with
this drug and is manifested by difficulty walking and numbness
and tingling in the fingers and toes. will cause permanent
damage if not treated.
4/16/2026, 12:59:57 PM
