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NR 507 Edapt Week : Obstructive & Restrictive Lung Diseases – 100 Q&A with Rationales | COPD, Asthma, Interstitial Lung Disease

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This comprehensive Edapt study guide is fully updated for the 2026–2027 academic year and is specifically designed for NR 507 Advanced Pathophysiology – Week 3. It contains 100 real exam-style questions with verified answers and detailed rationales, covering obstructive lung diseases (COPD, emphysema, chronic bronchitis, asthma), restrictive lung diseases (interstitial lung disease, idiopathic pulmonary fibrosis, sarcoidosis, hypersensitivity pneumonitis, pneumoconioses), pulmonary function test interpretation (FEV1/FVC ratio, TLC, DLCO), pathophysiology of airway obstruction and restriction, pharmacological management (bronchodilators, corticosteroids, anti-IgE, antifibrotics), and clinical correlations. High-yield for NR 507 Edapt Week 3 assessments and graduate-level advanced pathophysiology.

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NR 507 EDAPT WEEK 3
OBSTRUCTIVE AND RESTRICTIVE LUNG
DISEASES
CHRONIC OBSTRUCTIVE PULMONARY
DISEASE
ASTHMA
INTERSTITIAL LUNG DISEASE
QUESTIONS AND ANSWERS
MOST RECENTLY UPDATED 2026 2027


SECTION 1 OBSTRUCTIVE LUNG DISEASES
OVERVIEW
QUESTIONS 1 TO 20


1 A patient with chronic obstructive pulmonary
disease has a forced expiratory volume in 1 second
to forced vital capacity ratio of 0.65. Which
interpretation is correct?
A Normal

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B Obstructive pattern
C Restrictive pattern
D Mixed pattern


ANSWER B
Rationale An FEV1 to FVC ratio less than 0.70
indicates obstructive lung disease. In restrictive
disease, the ratio is normal or increased.


2 Which statement correctly describes the primary
pathophysiology of chronic obstructive pulmonary
disease?
A Reversible airway inflammation
B Fixed airway obstruction with destruction of lung
parenchyma
C Restriction of lung volume due to chest wall
stiffness
D Interstitial fibrosis

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ANSWER B
Rationale COPD is characterized by fixed,
irreversible airway obstruction due to chronic
bronchitis and emphysema, with destruction of
alveolar walls and loss of elastic recoil.


3 A patient with COPD has a PaCO2 of 55 mm Hg.
The nurse understands that this patient is at risk for
which acid‑base disorder?
A Respiratory acidosis
B Respiratory alkalosis
C Metabolic acidosis
D Metabolic alkalosis


ANSWER A
Rationale An elevated PaCO2 above 45 mm Hg
indicates hypercapnia and respiratory acidosis due to
inadequate alveolar ventilation.

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4 Which cell type is primarily responsible for the
destruction of alveolar walls in emphysema?
A Neutrophils
B Eosinophils
C Macrophages
D Mast cells


ANSWER A
Rationale Neutrophils and macrophages release
proteases such as elastase that break down elastin
and alveolar walls, leading to emphysema.


5 A patient with alpha‑1 antitrypsin deficiency is at
risk for developing which lung disease?
A Asthma
B Emphysema
C Pulmonary fibrosis
D Sarcoidosis

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