SUMMER 2026
PREDICTED PAPER
A Level Chemistry B (Salters)
H433/03 Practical skills in chemistry
OCR
Time allowed: 1 hour 30 minutes
You must have:
• the Practical Insert (inside this document)
• the Data Sheet for Chemistry B
You can use:
a scientific or graphical calculator
a ruler (cm/mm)
Please write clearly in black ink. Do not write in the barcodes.
Centre number Candidate number
First name(s)
Last name
INSTRUCTIONS
• Use black ink. You can use an HB pencil, but only for graphs and diagrams.
• Write your answer to each question in the space provided. If you need extra space
use the lined pages at the end of this booklet. The question numbers must be clearly
shown.
• Answer all the questions.
• Where appropriate, your answer should be supported with working. Marks might
be given for using a correct method, even if your answer is wrong.
INFORMATION
• The total mark for this paper is 60.
• The marks for each question are shown in brackets [ ].
• Quality of extended response will be assessed in questions marked with an asterisk (*).
• This document has 20 pages.
ADVICE
• Read each question carefully before you start your answer.
Turn over
for more: tyrionpapers.com
, 2
1 A pair of chemistry students are asked to prepare a sample of 2-hydroxy-2-phenylpropanenitrile, a
chiral compound used as a precursor in pharmaceutical synthesis.
They use the two-step synthesis shown in Fig. 1.1.
Fig. 1.1
Step 1
Benzene + Ethanoyl anhyd. AlCl₃ Acetophenone + HCl
C₆H₆ chloride C₆H₅COCH₃ (gas)
CH₃COCl
Step 2
(KCN / dil.
Acetophenone + H₂SO₄)reflux 2-hydroxy-2-phenylpropanenitrile
C₆H₅COCH₃ HCN C₆H₅C(OH)(CH₃)CN
(chiral product)
(a) Identify the two functional groups in 2-hydroxy-2-phenylpropanenitrile, apart from the
benzene ring.
...................................................................................................................................
................................................................................................................................... [2]
(b) The reactant, acetophenone, can be made from benzene in the one-step reaction
shown below.
Sn / conc. HCl
reflux
Phenol dil. HNO₃ 4-nitrophenol 4-aminophenol
C₆H₅OH HOC₆H₄NO₂ HOC₆H₄NH₂
Name the type of reaction for each step.
...................................................................................................................................
................................................................................................................................... [2]
for more: tyrionpapers.com
, 3
(c) Fig. 1.2 shows some information found on a bottle of potassium cyanide (KCN).
Fig 1.2
Hazards
Potassium
cyanide Fatal if swallowed, inhaled or in contact with skin
KCN Reacts with acids to release highly toxic HCN gas
Harmful to aquatic environment — long lasting effects
The students use the information in Fig. 1.2 to write a risk assessment for potassium
cyanide.
Suggest three precautions that the students should take when using potassium cyanide.
...................................................................................................................................
...................................................................................................................................
...................................................................................................................................
...................................................................................................................................
...................................................................................................................................
...................................................................................................................................
...................................................................................................................................
................................................................................................................................... [2]
for more: tyrionpapers.com
PREDICTED PAPER
A Level Chemistry B (Salters)
H433/03 Practical skills in chemistry
OCR
Time allowed: 1 hour 30 minutes
You must have:
• the Practical Insert (inside this document)
• the Data Sheet for Chemistry B
You can use:
a scientific or graphical calculator
a ruler (cm/mm)
Please write clearly in black ink. Do not write in the barcodes.
Centre number Candidate number
First name(s)
Last name
INSTRUCTIONS
• Use black ink. You can use an HB pencil, but only for graphs and diagrams.
• Write your answer to each question in the space provided. If you need extra space
use the lined pages at the end of this booklet. The question numbers must be clearly
shown.
• Answer all the questions.
• Where appropriate, your answer should be supported with working. Marks might
be given for using a correct method, even if your answer is wrong.
INFORMATION
• The total mark for this paper is 60.
• The marks for each question are shown in brackets [ ].
• Quality of extended response will be assessed in questions marked with an asterisk (*).
• This document has 20 pages.
ADVICE
• Read each question carefully before you start your answer.
Turn over
for more: tyrionpapers.com
, 2
1 A pair of chemistry students are asked to prepare a sample of 2-hydroxy-2-phenylpropanenitrile, a
chiral compound used as a precursor in pharmaceutical synthesis.
They use the two-step synthesis shown in Fig. 1.1.
Fig. 1.1
Step 1
Benzene + Ethanoyl anhyd. AlCl₃ Acetophenone + HCl
C₆H₆ chloride C₆H₅COCH₃ (gas)
CH₃COCl
Step 2
(KCN / dil.
Acetophenone + H₂SO₄)reflux 2-hydroxy-2-phenylpropanenitrile
C₆H₅COCH₃ HCN C₆H₅C(OH)(CH₃)CN
(chiral product)
(a) Identify the two functional groups in 2-hydroxy-2-phenylpropanenitrile, apart from the
benzene ring.
...................................................................................................................................
................................................................................................................................... [2]
(b) The reactant, acetophenone, can be made from benzene in the one-step reaction
shown below.
Sn / conc. HCl
reflux
Phenol dil. HNO₃ 4-nitrophenol 4-aminophenol
C₆H₅OH HOC₆H₄NO₂ HOC₆H₄NH₂
Name the type of reaction for each step.
...................................................................................................................................
................................................................................................................................... [2]
for more: tyrionpapers.com
, 3
(c) Fig. 1.2 shows some information found on a bottle of potassium cyanide (KCN).
Fig 1.2
Hazards
Potassium
cyanide Fatal if swallowed, inhaled or in contact with skin
KCN Reacts with acids to release highly toxic HCN gas
Harmful to aquatic environment — long lasting effects
The students use the information in Fig. 1.2 to write a risk assessment for potassium
cyanide.
Suggest three precautions that the students should take when using potassium cyanide.
...................................................................................................................................
...................................................................................................................................
...................................................................................................................................
...................................................................................................................................
...................................................................................................................................
...................................................................................................................................
...................................................................................................................................
................................................................................................................................... [2]
for more: tyrionpapers.com
