CPHON Outline Complete Exam Study Guide with Complete Solutions
CPHON Outline Complete Exam Study Guide with Complete Solutions chemo - Correct Answer - kills cancer cells as they are dividing/replicating - G0: resting phase; hardest phase of cell cycle to kill cancer cells Retinoic acid (ATRA) - Correct Answer - used to treat APML - brings about maturation of promyelocytic blasts and the rapid resolution of the coagulopathy associated with treatment of APML - not curative as single agent but has improved remission rates, significantly reduced relapse rates & enhanced cure rates ritux - Correct Answer - monoclonal antibody - treats relapsed/refractory B cell lymphomas, CD20+ NHL, PTLD, and cGVHD. - activity directed against CD20 antigen present on the surface of normal and malignant B lymphocytes and works with the immune system to induce B cell lysis - side effects: fever, chills, rigors, rash cisplatin - Correct Answer - causes severe electrolyte imbalances, including hypomagnesemia, which can cause arrhythmias. - amifostine or thiosulfate may be used to prevent ototoxicity asparaginase - Correct Answer - risk factor for pancreatitis - symptoms for pancreatitis: epigastric/abdominal pain, fever, tachycardia, hypotension, N/V, increased amylase/lipase, hypoglycemia, hypoactive bowel sounds
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