2
pharm exam 1 Galen questions with accurate detailed
|| || || || || || || ||
answers
When the drug is in bloodstream after administration, is disintegrated out of stomach this is
|| || || || || || || || || || || || || ||
called?
|| ||
A. metabolism
||
B. absorption
||
C. excretion
||
D. distribution - ✔✔B
|| || ||
The movement of a drug from circulatory system to body tissues is called what?
|| || || || || || || || || || || || ||
A. distribution
||
B. metabolism
||
C. excretion
||
D. absorption - ✔✔A
|| || ||
This occurs when a drug is altered in chemical structure, most are done in the liver.
|| || || || || || || || || || || || || || ||
A. excretion
||
B. distribution
||
C. absorption
||
D. metabolism (biotransformation) - ✔✔D
|| || || ||
Elimination of drug from body through the following: kidneys, liver, feces, lungs, saliva,
|| || || || || || || || || || || || ||
sweat, breast milk. || || ||
A. excretion
||
,2
B. distribution
||
C. metabolism
||
D. absorption - ✔✔A
|| || ||
100% of a drug is used when it is given by which route?
|| || || || || || || || || || || ||
A. intramuscular (IM)
|| ||
B. intravenously (IV)
|| ||
C. subcutaneously (subq)
|| ||
D. orally (PO) - ✔✔B
|| || || ||
1st pass effect goes from the ____ to the ____.
|| || || || || || || || || ||
Only ____ % of med is going to make it through bloodstream due to this process. - ✔✔-
|| || || || || || || || || || || || || || || || ||
stomach, liver ||
-30%
What are the two routes that can skip the 1st pass effect?
|| || || || || || || || || || || ||
A. IM, sublingual
|| ||
B. IV, sublingual
|| ||
C. IM, subq
|| ||
D. IV, subq - ✔✔B
|| || || ||
When drug comes out of the first pass effect, it can go into the blood & be used in some way,
|| || || || || || || || || || || || || || || || || || || ||
the % of administered drug available for activity is called?
|| || || || || || || || || ||
A. peak
|| ||
,2
B. onset
|| ||
C. trough
||
D. bioavailable - ✔✔D
|| || ||
What in the blood have receptor sites that will grab onto, hold onto med and decreased
|| || || || || || || || || || || || || || || ||
therapeutic effect on drug? || || ||
A. carbs
||
B. electrolytes
||
C. proteins
||
D. cells - ✔✔C
|| || ||
What is it called when the drug causes the effect & do not get taken up by proteins in blood?
|| || || || || || || || || || || || || || || || || || ||
A. free drug
|| ||
B. extended release drug
|| || ||
C. protein binding drug - ✔✔A
|| || || || ||
When you take TWO high protein binding drugs the effect of the med is going to be _____
|| || || || || || || || || || || || || || || || || ||
effect on the body.
|| || || ||
They are going to compete with one another for ____ sites which makes them become ____
|| || || || || || || || || || || || || || || ||
- ✔✔higher,
|| ||
protein, free drugs || ||
When a med has a ____ half life you may only need to take that med a couple times a week.
|| || || || || || || || || || || || || || || || || || || || ||
, 2
When a med has a ____ half life, it may need to be taken more often because when it ____
|| || || || || || || || || || || || || || || || || || || ||
it becomes ____ therapeutic - ✔✔long,
|| || || || || ||
short, decreases, less || ||
When a drug becomes therapeutic this is called?
|| || || || || || || ||
A. onset
|| ||
B. peak
||
C. duration of action
|| || ||
The length of time a drug exerts a therapeutic effect is called?
|| || || || || || || || || || ||
A. duration of action
|| || ||
B. peak
||
C. onset
|| ||
This occurs when a drug reaches its highest concentration in blood.
|| || || || || || || || || ||
A. onset
||
B. duration
||
C. peak - ✔✔-A
|| || ||
-A
-C
Lowest conc of drug & it measures rate at which drug is eliminated, these labs are drawn
|| || || || || || || || || || || || || || || || ||
just before the next dose of drug regardless of route.
|| || || || || || || || ||
pharm exam 1 Galen questions with accurate detailed
|| || || || || || || ||
answers
When the drug is in bloodstream after administration, is disintegrated out of stomach this is
|| || || || || || || || || || || || || ||
called?
|| ||
A. metabolism
||
B. absorption
||
C. excretion
||
D. distribution - ✔✔B
|| || ||
The movement of a drug from circulatory system to body tissues is called what?
|| || || || || || || || || || || || ||
A. distribution
||
B. metabolism
||
C. excretion
||
D. absorption - ✔✔A
|| || ||
This occurs when a drug is altered in chemical structure, most are done in the liver.
|| || || || || || || || || || || || || || ||
A. excretion
||
B. distribution
||
C. absorption
||
D. metabolism (biotransformation) - ✔✔D
|| || || ||
Elimination of drug from body through the following: kidneys, liver, feces, lungs, saliva,
|| || || || || || || || || || || || ||
sweat, breast milk. || || ||
A. excretion
||
,2
B. distribution
||
C. metabolism
||
D. absorption - ✔✔A
|| || ||
100% of a drug is used when it is given by which route?
|| || || || || || || || || || || ||
A. intramuscular (IM)
|| ||
B. intravenously (IV)
|| ||
C. subcutaneously (subq)
|| ||
D. orally (PO) - ✔✔B
|| || || ||
1st pass effect goes from the ____ to the ____.
|| || || || || || || || || ||
Only ____ % of med is going to make it through bloodstream due to this process. - ✔✔-
|| || || || || || || || || || || || || || || || ||
stomach, liver ||
-30%
What are the two routes that can skip the 1st pass effect?
|| || || || || || || || || || || ||
A. IM, sublingual
|| ||
B. IV, sublingual
|| ||
C. IM, subq
|| ||
D. IV, subq - ✔✔B
|| || || ||
When drug comes out of the first pass effect, it can go into the blood & be used in some way,
|| || || || || || || || || || || || || || || || || || || ||
the % of administered drug available for activity is called?
|| || || || || || || || || ||
A. peak
|| ||
,2
B. onset
|| ||
C. trough
||
D. bioavailable - ✔✔D
|| || ||
What in the blood have receptor sites that will grab onto, hold onto med and decreased
|| || || || || || || || || || || || || || || ||
therapeutic effect on drug? || || ||
A. carbs
||
B. electrolytes
||
C. proteins
||
D. cells - ✔✔C
|| || ||
What is it called when the drug causes the effect & do not get taken up by proteins in blood?
|| || || || || || || || || || || || || || || || || || ||
A. free drug
|| ||
B. extended release drug
|| || ||
C. protein binding drug - ✔✔A
|| || || || ||
When you take TWO high protein binding drugs the effect of the med is going to be _____
|| || || || || || || || || || || || || || || || || ||
effect on the body.
|| || || ||
They are going to compete with one another for ____ sites which makes them become ____
|| || || || || || || || || || || || || || || ||
- ✔✔higher,
|| ||
protein, free drugs || ||
When a med has a ____ half life you may only need to take that med a couple times a week.
|| || || || || || || || || || || || || || || || || || || || ||
, 2
When a med has a ____ half life, it may need to be taken more often because when it ____
|| || || || || || || || || || || || || || || || || || || ||
it becomes ____ therapeutic - ✔✔long,
|| || || || || ||
short, decreases, less || ||
When a drug becomes therapeutic this is called?
|| || || || || || || ||
A. onset
|| ||
B. peak
||
C. duration of action
|| || ||
The length of time a drug exerts a therapeutic effect is called?
|| || || || || || || || || || ||
A. duration of action
|| || ||
B. peak
||
C. onset
|| ||
This occurs when a drug reaches its highest concentration in blood.
|| || || || || || || || || ||
A. onset
||
B. duration
||
C. peak - ✔✔-A
|| || ||
-A
-C
Lowest conc of drug & it measures rate at which drug is eliminated, these labs are drawn
|| || || || || || || || || || || || || || || || ||
just before the next dose of drug regardless of route.
|| || || || || || || || ||
