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Janeway’s Immunology Chapter 16 – Immunology Course, Academic Year – Study Notes and Review Material

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This document covers Chapter 16 from Janeway’s Immunology, focusing on advanced immune system concepts and responses. It supports understanding through structured explanations and key topic summaries. Ideal for medical and health science students preparing for exams.

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1
Janeways Immunology - chapter 16
(UPDATED:Janeways Immunology - chapter 16: 2026 - 2027 VERIFIED STUDY GUIDE). !!!!!!!!!!!!!!
Study online at https://quizlet.com/_fx6e5c

1. Vaccines can be based on two different things.... 1. attenuated
pathogens
2. material from
killed organisms

2. Attenuated organisms Stimulates pro-
tected immunity
but does not cause
disease

3. Features of effective vaccines 1. Safe - must not
cause illness or
death
2. Protective -
must fro vide pro-
tection from live
pathogen
3. Gives sustained
protection
4. Induces neutral-
izing antibody
5. Induces protec-
tive t-cells
6. Practical - low
cost per dose,
easy administra-
tion, few side ef-
fects

4. Smallpox Bólusótt
Eradicated in 1979
due to vaccination

5. Polio Mænusótt
WHO aims to
eradicate polio

6. Polysaccharide immunizations - T-cell indepen-
dent immune acti-
2026/04/06 4/6/2026, 6:29:41 PM 4/6/2026, 6:29:38 PM
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, 2
Janeways Immunology - chapter 16
(UPDATED:Janeways Immunology - chapter 16: 2026 - 2027 VERIFIED STUDY GUIDE). !!!!!!!!!!!!!!
Study online at https://quizlet.com/_fx6e5c
vators
- Do NOT induce
immune response
in babies under 2
years
- Activate ONLY
IgM
- DO NOT AC-
TIVATE immune
memory
- used in adults

7. Protein connected polysaccharides T-cell dependent
- cause immune
response in young
babies
- create antibod-
ies: IgM - IgA/IgG
- Create memory
cells
- SAMSPIL b and t
cells

8. What sort of immunisation material was used in Protein connected
meningococcal? polysaccharide

9. More babies die from ____ that other contagious dis- Lung disease
eases

10. Which is more effective, Live-attenuated viral vac- Live-attenuated vi-
cines or killed vaccines? explain. ral vaccines more
effective than
killed vaccines can
be made safer
with recombinant
DNA technology .
Killed vaccines are
unable to repli-
cate. Live-attenu-
2026/04/06 4/6/2026, 6:29:41 PM
ated viral vaccines
4/6/2026, 6:29:38 PM
2/7

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