TEST BANK H
PATHOPHYSIOLOGY
THE BIOLOGIC BASIS FOR DISEASE IN ADULTS AND CHILDREN
H H H H H H H H
8th Edition
H
Kathryn L. McCance, Sue E. Huether
H H H H H
, 2
Contents
Chapter 01: Cellular Biology.......................................................................................................................... 4
H H H
Chapter 02: Altered Cellular and Tissue Biology: Environmental Agents ................................................... 18
H H H H H H H H
Chapter 03: The Cellular Environment: Fluids and Electrolytes, Acids and Bases ...................................... 31
H H H H H H H H H H
Chapter 04: Genes and Genetic Diseases ................................................................................................... 44
H H H H H
Chapter 05: Genes, Environment-Lifestyle, and Common Diseases ........................................................... 55
H H H H H H
Chapter 06: Epigenetics and Disease .......................................................................................................... 63
H H H H
Chapter 07: Innate Immunity: Inflammation and Wound Healing ............................................................. 68
H H H H H H H
Chapter 08: Adaptive Immunity .................................................................................................................. 83
H H H
Chapter 09: Alterations in Immunity and Inflammation ............................................................................. 95
H H H H H H
Chapter 10: Infection ................................................................................................................................ 108
H H
Chapter 11: Stress and Disease ................................................................................................................. 117
H H H H
Chapter 12: Cancer Biology....................................................................................................................... 124
H H H
Chapter 13: Cancer Epidemiology ............................................................................................................. 137
H H H
Chapter 14: Cancer in Children ................................................................................................................. 143
H H H H
Chapter 15: Structure and Function of the Neurologic System ................................................................ 148
H H H H H H H H
Chapter 16: Pain, Temperature Regulation, Sleep, and Sensory Function ............................................... 159
H H H H H H H H
Chapter 17: Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function ............... 174
H H H H H H H H H H
Chapter 18: Disorders of the Central and Peripheral Nervous Systems and the Neuromuscular Junction
H H H H H H H H H H H H H
.................................................................................................................................................................. 188
Chapter 19: Neurobiology of Schizophrenia, Mood Disorders, and Anxiety Disorders ............................ 199
H H H H H H H H H
Chapter 20: Alterations of Neurologic Function in Children ..................................................................... 206
H H H H H H H
Chapter 21: Mechanisms of Hormonal Regulation ................................................................................... 213
H H H H H
Chapter 22: Alterations of Hormonal Regulation ..................................................................................... 222
H H H H H
Chapter 23: Obesity and Disorders of Nutrition ....................................................................................... 234
H H H H H H
Chapter 24: Structure and Function of the Reproductive Systems........................................................... 239
H H H H H H H H
Chapter 25: Alterations of the Female Reproductive System................................................................... 249
H H H H H H H
Chapter 26: Alterations of the Male Reproductive System ...................................................................... 259
H H H H H H H
Chapter 27: Sexually Transmitted Infections............................................................................................. 265
H H H H
Chapter 28: Structure and Function of the Hematologic System ............................................................. 273
H H H H H H H H
Chapter 29: Alterations of Erythrocytes, Platelets, and Hemostatic Function ......................................... 283
H H H H H H H H
, 3
Chapter 30: Alterations of Leukocyte and Lymphoid Function ................................................................. 293
H H H H H H H
Chapter 31: Alterations of Hematologic Function in Children .................................................................. 300
H H H H H H H
Chapter 32: Structure and Function of the Cardiovascular and Lymphatic Systems ................................ 311
H H H H H H H H H H
Chapter 33: Alterations of Cardiovascular Function ................................................................................. 324
H H H H H
Chapter 34: Alterations of Cardiovascular Function in Children ............................................................... 338
H H H H H H H
Chapter 35: Structure and Function of the Pulmonary System ................................................................ 346
H H H H H H H H
Chapter 36: Alterations of Pulmonary Function ....................................................................................... 356
H H H H H
Chapter 37: Alterations of Pulmonary Function in Children ..................................................................... 373
H H H H H H H
Chapter 38: Structure and Function of the Renal and Urologic Systems.................................................. 381
H H H H H H H H H H
Chapter 39: Alterations of Renal and Urinary Tract Function................................................................... 391
H H H H H H H H
Chapter 40: Alterations of Renal and Urinary Tract Function in Children ................................................ 401
H H H H H H H H H H
Chapter 41: Structure and Function of the Digestive System ................................................................... 409
H H H H H H H H
Chapter 42: Alterations of Digestive Function .......................................................................................... 421
H H H H H
Chapter 43: Alterations of Digestive Function in Children........................................................................ 432
H H H H H H H
Chapter 44: Structure and Function of the Musculoskeletal System ....................................................... 441
H H H H H H H H
Chapter 45: Alterations of Musculoskeletal Function ............................................................................... 453
H H H H H
Chapter 46: Alterations of Musculoskeletal Function in Children ............................................................ 466
H H H H H H H
Chapter 47: Structure, Function, and Disorders of the Integument ......................................................... 475
H H H H H H H H
Chapter 48: Alterations of the Integument in Children ............................................................................ 486
H H H H H H H
Chapter 49: Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults .................................... 494
H H H H H H H H H H
Chapter 50: Shock, Multiple Organ Dysfunction Syndrome, and Burns in Children ................................. 502
H H H H H H H H H H
, Test Bank - Pathophysiology: The Biologic Basis for Disease in Adults and Children (8th)
H H H H H H H H H H H H H H 4
Chapter 01: Cellular Biology
H H H
MULTIPLE CHOICE H
1. Which statement best describes the cellular function of metabolic absorption?
H H H H H H H H H
a. Cells can produce proteins.
H H H
b. Cells can secrete digestive enzymes.
H H H H
c. Cells can take in and use nutrients.
H H H H H H
d. Cells can synthesize fats.H H H
ANS: H C
In metabolic absorption, all cells take in and use nutrients and other substances from their
H H H H H H H H H H H H H H
Hsurroundings. The remaining options are not inclusive in their descriptions of cellular metabolic
H H H H H H H H H H H H
Habsorption.
PTS: H H 1 DIF: Cognitive Level: Remembering H H
2. Where is most of a cell’s genetic information, including RNA and DNA, contained?
H H H H H H H H H H H H
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Lysosome
ANS: H C
The nucleus contains the nucleolus, a small dense structure composed largely of RNA, most of
H H H H H H H H H H H H H H
the cellular DNA, and the DNA-binding proteins, such as the histones, which regulate its
H H H H H H H H H H H H H H
activity. The mitochondria are responsible for cellular respiration and energy production.
H H H H H H H H H H H
Ribosomes’ chief function is to provide sites for cellular protein synthesis. Lysosomes function
H H H H H H H H H H H H
as the intracellular digestive system.
H H H H H
PTS: H H 1 DIF: Cognitive Level: Remembering H H
3. Which component of the cell produces hydrogen peroxide (H2O2) by using oxygen to
H H H H H H H H H H H H
remove hydrogen atoms from specific substrates in an oxidative reaction?
H H H H H H H H H H
a. Lysosomes
b. Peroxisomes
c. Ribosomes
d. Endosome
ANS: H B
PATHOPHYSIOLOGY
THE BIOLOGIC BASIS FOR DISEASE IN ADULTS AND CHILDREN
H H H H H H H H
8th Edition
H
Kathryn L. McCance, Sue E. Huether
H H H H H
, 2
Contents
Chapter 01: Cellular Biology.......................................................................................................................... 4
H H H
Chapter 02: Altered Cellular and Tissue Biology: Environmental Agents ................................................... 18
H H H H H H H H
Chapter 03: The Cellular Environment: Fluids and Electrolytes, Acids and Bases ...................................... 31
H H H H H H H H H H
Chapter 04: Genes and Genetic Diseases ................................................................................................... 44
H H H H H
Chapter 05: Genes, Environment-Lifestyle, and Common Diseases ........................................................... 55
H H H H H H
Chapter 06: Epigenetics and Disease .......................................................................................................... 63
H H H H
Chapter 07: Innate Immunity: Inflammation and Wound Healing ............................................................. 68
H H H H H H H
Chapter 08: Adaptive Immunity .................................................................................................................. 83
H H H
Chapter 09: Alterations in Immunity and Inflammation ............................................................................. 95
H H H H H H
Chapter 10: Infection ................................................................................................................................ 108
H H
Chapter 11: Stress and Disease ................................................................................................................. 117
H H H H
Chapter 12: Cancer Biology....................................................................................................................... 124
H H H
Chapter 13: Cancer Epidemiology ............................................................................................................. 137
H H H
Chapter 14: Cancer in Children ................................................................................................................. 143
H H H H
Chapter 15: Structure and Function of the Neurologic System ................................................................ 148
H H H H H H H H
Chapter 16: Pain, Temperature Regulation, Sleep, and Sensory Function ............................................... 159
H H H H H H H H
Chapter 17: Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function ............... 174
H H H H H H H H H H
Chapter 18: Disorders of the Central and Peripheral Nervous Systems and the Neuromuscular Junction
H H H H H H H H H H H H H
.................................................................................................................................................................. 188
Chapter 19: Neurobiology of Schizophrenia, Mood Disorders, and Anxiety Disorders ............................ 199
H H H H H H H H H
Chapter 20: Alterations of Neurologic Function in Children ..................................................................... 206
H H H H H H H
Chapter 21: Mechanisms of Hormonal Regulation ................................................................................... 213
H H H H H
Chapter 22: Alterations of Hormonal Regulation ..................................................................................... 222
H H H H H
Chapter 23: Obesity and Disorders of Nutrition ....................................................................................... 234
H H H H H H
Chapter 24: Structure and Function of the Reproductive Systems........................................................... 239
H H H H H H H H
Chapter 25: Alterations of the Female Reproductive System................................................................... 249
H H H H H H H
Chapter 26: Alterations of the Male Reproductive System ...................................................................... 259
H H H H H H H
Chapter 27: Sexually Transmitted Infections............................................................................................. 265
H H H H
Chapter 28: Structure and Function of the Hematologic System ............................................................. 273
H H H H H H H H
Chapter 29: Alterations of Erythrocytes, Platelets, and Hemostatic Function ......................................... 283
H H H H H H H H
, 3
Chapter 30: Alterations of Leukocyte and Lymphoid Function ................................................................. 293
H H H H H H H
Chapter 31: Alterations of Hematologic Function in Children .................................................................. 300
H H H H H H H
Chapter 32: Structure and Function of the Cardiovascular and Lymphatic Systems ................................ 311
H H H H H H H H H H
Chapter 33: Alterations of Cardiovascular Function ................................................................................. 324
H H H H H
Chapter 34: Alterations of Cardiovascular Function in Children ............................................................... 338
H H H H H H H
Chapter 35: Structure and Function of the Pulmonary System ................................................................ 346
H H H H H H H H
Chapter 36: Alterations of Pulmonary Function ....................................................................................... 356
H H H H H
Chapter 37: Alterations of Pulmonary Function in Children ..................................................................... 373
H H H H H H H
Chapter 38: Structure and Function of the Renal and Urologic Systems.................................................. 381
H H H H H H H H H H
Chapter 39: Alterations of Renal and Urinary Tract Function................................................................... 391
H H H H H H H H
Chapter 40: Alterations of Renal and Urinary Tract Function in Children ................................................ 401
H H H H H H H H H H
Chapter 41: Structure and Function of the Digestive System ................................................................... 409
H H H H H H H H
Chapter 42: Alterations of Digestive Function .......................................................................................... 421
H H H H H
Chapter 43: Alterations of Digestive Function in Children........................................................................ 432
H H H H H H H
Chapter 44: Structure and Function of the Musculoskeletal System ....................................................... 441
H H H H H H H H
Chapter 45: Alterations of Musculoskeletal Function ............................................................................... 453
H H H H H
Chapter 46: Alterations of Musculoskeletal Function in Children ............................................................ 466
H H H H H H H
Chapter 47: Structure, Function, and Disorders of the Integument ......................................................... 475
H H H H H H H H
Chapter 48: Alterations of the Integument in Children ............................................................................ 486
H H H H H H H
Chapter 49: Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults .................................... 494
H H H H H H H H H H
Chapter 50: Shock, Multiple Organ Dysfunction Syndrome, and Burns in Children ................................. 502
H H H H H H H H H H
, Test Bank - Pathophysiology: The Biologic Basis for Disease in Adults and Children (8th)
H H H H H H H H H H H H H H 4
Chapter 01: Cellular Biology
H H H
MULTIPLE CHOICE H
1. Which statement best describes the cellular function of metabolic absorption?
H H H H H H H H H
a. Cells can produce proteins.
H H H
b. Cells can secrete digestive enzymes.
H H H H
c. Cells can take in and use nutrients.
H H H H H H
d. Cells can synthesize fats.H H H
ANS: H C
In metabolic absorption, all cells take in and use nutrients and other substances from their
H H H H H H H H H H H H H H
Hsurroundings. The remaining options are not inclusive in their descriptions of cellular metabolic
H H H H H H H H H H H H
Habsorption.
PTS: H H 1 DIF: Cognitive Level: Remembering H H
2. Where is most of a cell’s genetic information, including RNA and DNA, contained?
H H H H H H H H H H H H
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Lysosome
ANS: H C
The nucleus contains the nucleolus, a small dense structure composed largely of RNA, most of
H H H H H H H H H H H H H H
the cellular DNA, and the DNA-binding proteins, such as the histones, which regulate its
H H H H H H H H H H H H H H
activity. The mitochondria are responsible for cellular respiration and energy production.
H H H H H H H H H H H
Ribosomes’ chief function is to provide sites for cellular protein synthesis. Lysosomes function
H H H H H H H H H H H H
as the intracellular digestive system.
H H H H H
PTS: H H 1 DIF: Cognitive Level: Remembering H H
3. Which component of the cell produces hydrogen peroxide (H2O2) by using oxygen to
H H H H H H H H H H H H
remove hydrogen atoms from specific substrates in an oxidative reaction?
H H H H H H H H H H
a. Lysosomes
b. Peroxisomes
c. Ribosomes
d. Endosome
ANS: H B
