Maryland Pharmacist Licensing Exam 2026/2027 | Complete
NAPLEX-Style Q&A with Well-Elaborated Answers &
Rationales | 100% Verified Solutions | Instant PDF Download
IMPORTANT: Read This First
Preparing for the NAPLEX? Before using these practice questions, you should understand the structure
of the exam. The North American Pharmacist Licensure Examination (NAPLEX) is a 225-question, 6-
hour exam that is scored on a scale of 0 to 150, with a passing scaled score of 75. Results are reported as
pass or fail, and candidates are allowed 5 attempts to pass the exam. The exam blueprint evolves
regularly, with recent changes emphasizing clinical decision-making and pharmacotherapy over trivia.
Additionally, to practice pharmacy in Maryland, you must also pass the Multistate Pharmacy
Jurisprudence Examination (MPJE) or the Uniform Pharmacy Jurisprudence Examination (UMPJE) with a
Maryland-specific module. Use these practice questions to assess your readiness, but always
supplement with current official resources.
Federal and Maryland Pharmacy Law
Question 1: Pharmacist Licensure Renewal (Maryland)
A pharmacist in Maryland must complete how many hours of continuing pharmaceutical education
(CPE) to renew a license for a full two-year renewal period? What specific hour requirements must be
met, and what is the first-renewal waiver?
• A) 15 hours total, with no specific topic requirements. First renewal requires 5 hours.
• B) 20 hours total, all must be live. First renewal is waived entirely.
• C) 30 hours total, with at least 2 hours of live credit. First renewal after graduation may be
waived.
• D) 40 hours total, with 4 hours of sterile compounding. No waiver is available.
Correct Answer : C
Detailed Rationale: Under Maryland Health Occupations Code §12-309, a pharmacist must complete 30
hours of approved continuing pharmaceutical education within the preceding two years to renew a
license. At least 2 hours must be live (synchronous) credit. The remaining 28 hours may be from home
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study. The first renewal following original licensure may be granted without any continuing education if
the license was obtained within one year of completing pharmaceutical education.
Question 2: Prescription Transfer (Federal/General)
A pharmacist at Pharmacy A receives a request from a pharmacist at Pharmacy B to transfer a valid,
refillable prescription for a non-controlled substance. Which of the following statements regarding the
transfer is correct?
• A) The prescription may be transferred only once, and the transferring pharmacist must
document the name of the receiving pharmacy and the transferring pharmacist's initials.
• B) The prescription may be transferred an unlimited number of times, and no documentation is
required.
• C) The prescription may be transferred only to another pharmacy owned by the same
corporation.
• D) The prescription may be transferred only if the patient is present at Pharmacy B at the time
of transfer.
Correct Answer : A
Detailed Rationale: For non-controlled substances, a prescription may be transferred once (i.e., the
original prescription is voided and the new pharmacy becomes the primary) unless the pharmacies share
an online, real-time database. The transferring pharmacist must document: the name of the secondary
pharmacy, the name of the transferring pharmacist, the date of transfer, and the original prescription
number. The patient does not need to be present at the time of transfer.
Question 3: Federal Controlled Substance Scheduling (Federal)
Under federal law, which of the following schedules contains drugs that have a high potential for abuse,
have no currently accepted medical use in treatment in the United States, and have a lack of accepted
safety for use under medical supervision?
• A) Schedule I
• B) Schedule II
• C) Schedule III
• D) Schedule IV
Correct Answer : A
Detailed Rationale: Schedule I drugs meet three criteria: (1) high potential for abuse; (2) no currently
accepted medical use in treatment in the US; and (3) lack of accepted safety for use under medical
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supervision. Examples include heroin, LSD, and marijuana. Schedule II drugs have a high abuse potential
but have accepted medical use (e.g., morphine, oxycodone).
Question 4: Pharmacist in Charge (PIC) Duties (Maryland)
A pharmacist has just been hired as the Pharmacist in Charge (PIC) of an independent community
pharmacy in Maryland. Which of the following is a primary duty of the PIC?
• A) Count and package all medications dispensed by the pharmacy.
• B) Provide final verification of all prescriptions and make decisions requiring professional
judgment.
• C) Perform all administrative tasks, including payroll and human resources.
• D) Clean and maintain all pharmacy equipment.
Correct Answer : B
Detailed Rationale: Under Maryland law and professional standards, the PIC is responsible for ensuring
that all prescriptions are filled correctly and safely. This includes providing final verification of all filled
prescriptions and making clinical decisions that require a pharmacist's professional judgment. While the
PIC may also have administrative duties, these are not the primary legal responsibility.
Question 5: Collaborative Practice Agreements (Maryland – 2026 Update)
Effective July 1, 2026, which of the following changes to Maryland law regarding prescriber-pharmacist
collaborative practice agreements (CPAs) takes effect?
• A) All CPAs must be submitted to the Maryland Board of Physicians for approval.
• B) Prescribers are no longer required to submit CPA agreements to the health occupations
board that regulates the prescriber.
• C) CPAs are prohibited for controlled substances.
• D) Pharmacists may only enter CPAs with physicians, not nurse practitioners.
Correct Answer : B
Detailed Rationale: Maryland legislation effective July 1, 2026, repeals the requirement that authorized
prescribers submit prescriber-pharmacist agreements to the health occupations board that regulates
the prescriber. This reduces administrative burden while allowing pharmacists to continue practicing
under collaborative agreements.
Question 6: Dispensing Controlled Substances (Federal)
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A patient presents a written prescription for Adderall (amphetamine/dextroamphetamine) 10 mg,
quantity 30 tablets, with one refill authorized. The prescription is dated 15 days ago. Under federal law,
which of the following statements is correct regarding this prescription?
• A) The prescription is expired and cannot be filled.
• B) The prescription is valid for up to 180 days from the date written, but a Schedule II
prescription may be refilled only if authorized in writing by the prescriber.
• C) The prescription is valid for 6 months, and the refill is permitted without further
authorization.
• D) The prescription must be transmitted electronically; written prescriptions are no longer
accepted.
Correct Answer : B
Detailed Rationale: Adderall is a Schedule II controlled substance. Federal law (21 CFR §1306.22) allows
a Schedule II prescription to be filled up to 180 days from the date written (unless state law is more
restrictive). However, refills are not permitted on a Schedule II prescription unless the prescriber issues
a new prescription. The fact that the prescriber wrote "one refill" on the face of the prescription does
not make it valid; the patient must obtain a new prescription.
Question 7: Orange Book Purpose (Federal)
A pharmacist is asked by a physician whether a generic product can be substituted for a brand-name
medication. The pharmacist consults the FDA’s Orange Book. The primary purpose of the Orange Book
in pharmacy practice is to:
• A) Identify all drugs approved for safety and efficacy and provide information about therapeutic
equivalence.
• B) List all controlled substances and their schedules.
• C) Provide a list of all drugs currently under patent protection.
• D) Serve as a catalog of pharmaceutical pricing information.
Correct Answer : A
Detailed Rationale: The FDA’s Orange Book (Approved Drug Products with Therapeutic Equivalence
Evaluations) is an annual publication that identifies all drugs approved for safety and efficacy. It provides
information on therapeutic equivalence, allowing pharmacists to determine which generic products can
be substituted for brand-name drugs based on an “A” (therapeutically equivalent) or “B” (not
equivalent) rating.
Question 8: Anabolic Steroid Control (Federal)