APEA Neuro Pharmacology Test
Bank | Complete Questions &
Answers Study Pack A+
Guaranteed
• The patient who requires the LEAST cautionary measures when treated
with carbidopa/levodopa (Sinemet) is:
a 43-year-old woman with hypothyroidism.
a 45-year-old retired marine with secondary parkinsonism and a history
of post-traumatic stress disorder.
a 50-year-old woman with a history of obstructive sleep apnea.
a 55-year-old man with history a of myocardial infarction with residual
atrial arrhythmia. Answer: a 43-year-old woman with hypothyroidism.
• Benztropine (Cogentin), an anticholinergic, is NOT recommended for
use in patients with:
athetosis movements.
Huntington's chorea.
parkinsonism.
tardive dyskinesia. Answer: tardive dyskinesia.
,• A patient presenting with a transient ischemic attack (TIA) is taking
nifedipine (Adalat CC) for hypertension. Pharmacokinetics of nifedipine
may be altered in patients with:
renal insufficiency.
hepatic impairment.
irritable bowel disease.
G6PD deficiency. Answer: hepatic impairment.
• A medication used in a patient with a transient ischemic attack to
prevent platelet aggregation and produce an anti-inflammatory effect in
vessels by inhibiting prostaglandin synthesis is:
acetaminophen.
ibuprofen.
acetylsalicylic acid.
warfarin. Answer: acetylsalicylic acid.
• Carbidopa/levodopa (Sinemet) for the treatment of Parkinson's disease
is contraindicated in patients with:
diabetes.
history of peptic ulcer disease.
narrow-angle glaucoma.
wide-angle glaucoma. Answer: narrow-angle glaucoma.
• During initiation of treatment and escalation of doses, pramipexole
(Mirapex) and other dopamine agonists are known to cause:
, akathisia.
gastrointestinal bleeding.
orthostatic hypotension.
thrombocytopenia. Answer: orthostatic hypotension.
• Ergotamine alkaloids, such as dihydroergotamine (Migranal), are
indicated in the treatment of:
basilar migraine headaches.
cluster headaches.
migraine headaches (acute).
tension headaches. Answer: migraine headaches (acute).
• Patients who are taking rasagiline (Azilect) for the treatment of
Parkinson's disease should avoid other CYP1A2 inhibitors such as:
ciprofloxacin (Cipro).
clindamycin (Cleocin).
erythromycin base (Ery-Tab)
sulfamethoxazole/trimethoprim (Bactrim). Answer: ciprofloxacin
(Cipro).
• Beta-blockers, used for the prophylactic treatment of migraines, would
NOT be contraindicated in a patient with a history of:
ventricular arrhythmias.
2nd degree heart block.
Bank | Complete Questions &
Answers Study Pack A+
Guaranteed
• The patient who requires the LEAST cautionary measures when treated
with carbidopa/levodopa (Sinemet) is:
a 43-year-old woman with hypothyroidism.
a 45-year-old retired marine with secondary parkinsonism and a history
of post-traumatic stress disorder.
a 50-year-old woman with a history of obstructive sleep apnea.
a 55-year-old man with history a of myocardial infarction with residual
atrial arrhythmia. Answer: a 43-year-old woman with hypothyroidism.
• Benztropine (Cogentin), an anticholinergic, is NOT recommended for
use in patients with:
athetosis movements.
Huntington's chorea.
parkinsonism.
tardive dyskinesia. Answer: tardive dyskinesia.
,• A patient presenting with a transient ischemic attack (TIA) is taking
nifedipine (Adalat CC) for hypertension. Pharmacokinetics of nifedipine
may be altered in patients with:
renal insufficiency.
hepatic impairment.
irritable bowel disease.
G6PD deficiency. Answer: hepatic impairment.
• A medication used in a patient with a transient ischemic attack to
prevent platelet aggregation and produce an anti-inflammatory effect in
vessels by inhibiting prostaglandin synthesis is:
acetaminophen.
ibuprofen.
acetylsalicylic acid.
warfarin. Answer: acetylsalicylic acid.
• Carbidopa/levodopa (Sinemet) for the treatment of Parkinson's disease
is contraindicated in patients with:
diabetes.
history of peptic ulcer disease.
narrow-angle glaucoma.
wide-angle glaucoma. Answer: narrow-angle glaucoma.
• During initiation of treatment and escalation of doses, pramipexole
(Mirapex) and other dopamine agonists are known to cause:
, akathisia.
gastrointestinal bleeding.
orthostatic hypotension.
thrombocytopenia. Answer: orthostatic hypotension.
• Ergotamine alkaloids, such as dihydroergotamine (Migranal), are
indicated in the treatment of:
basilar migraine headaches.
cluster headaches.
migraine headaches (acute).
tension headaches. Answer: migraine headaches (acute).
• Patients who are taking rasagiline (Azilect) for the treatment of
Parkinson's disease should avoid other CYP1A2 inhibitors such as:
ciprofloxacin (Cipro).
clindamycin (Cleocin).
erythromycin base (Ery-Tab)
sulfamethoxazole/trimethoprim (Bactrim). Answer: ciprofloxacin
(Cipro).
• Beta-blockers, used for the prophylactic treatment of migraines, would
NOT be contraindicated in a patient with a history of:
ventricular arrhythmias.
2nd degree heart block.