Pharmacology Exam 1 -
Multiple Choice LATEST
QUESTIONS AND VERIFIED
CORRECT ANSWERS
GRADED A+
E. adipose tissue - CORRECT ANSWER-C
14. Drug X has a half-life of 6 hours. How much drug is left in the body 18 hours after an IV
injection of 1200 milligrams (mg)? - CORRECT ANSWER-B
15. Drugs that have demonstrated teratogenic effects in women are classified as Pregnancy
Category
A. B
B. C
C. D
D. X
E. NR - CORRECT ANSWER-D= x
16. When a drug increases the rate of drug metabolism of other drugs, the process is termed
,A. first-pass metabolism
B. enzyme induction
C. enzyme inhibition
D. enterohepatic cycling
E. microsomal inhibition - CORRECT ANSWER-B
17. The rate of drug absorption would be increased by which of the following?
A. drug ionization
B. water solubility
C. positively charged drug
D. negatively charged drug
E. lipid solubility - CORRECT ANSWER-E
18. Which factor of individual variation is dependent upon the patient's attitude toward
treatment?
A. weight
B. age
C. genetic variation
D. placebo effect
E. gender - CORRECT ANSWER-D
19. Which FDA pregnancy category would appear to be the safest for a developing fetus?
A. Category A
B. Category B
C. Category C
D. Category D
, E. Category X - CORRECT ANSWER-A
20. A 45-year-old female shop assistant is treated for heartburn with omeprazole. She notes
that the effect of a dose of omeprazole lasts much longer than that of a dose of the antacid drug
calcium carbonate she had previously taken. The active metabolite of omeprazole binds
covalently and irreversibly to a molecular structure involved in releasing protons into the gastric
juice. Drugs that modify their target structures through this mechanism are called
suicide substrates.
orphan drugs.
protein drugs.
competitive antagonists.
enantiomers. - CORRECT ANSWER-A
21. A 36-year-old male has been diagnosed with chronic myeloid leukemia. His oncologist
discusses treatment options with him. The patient is glad to hear that novel anticancer drugs
used to treat chronic myeloid leukemia have a much better risk-benefit ratio than older ones,
due to their improved selectivity. A major determinant for the selectivity of a given drug is
A) its target receptor ligand affinity.
B) its target receptor cell-type distribution.
C) its ionic interactions.
D) its hydrogen bonding.
E) its intrinsic activity. - CORRECT ANSWER-B
22. A 56-year-old man with chest pain is diagnosed with stable angina and treated with several
drugs including nitroglycerin. Every day he has to discontinue nitroglycerin for some hours to re-
establish reactivity of his body to the drug. The clinical observation of a rapidly decreasing
response to nitroglycerin after administration of just a few doses is called
idiosyncrasy.
tachyphylaxis.
Multiple Choice LATEST
QUESTIONS AND VERIFIED
CORRECT ANSWERS
GRADED A+
E. adipose tissue - CORRECT ANSWER-C
14. Drug X has a half-life of 6 hours. How much drug is left in the body 18 hours after an IV
injection of 1200 milligrams (mg)? - CORRECT ANSWER-B
15. Drugs that have demonstrated teratogenic effects in women are classified as Pregnancy
Category
A. B
B. C
C. D
D. X
E. NR - CORRECT ANSWER-D= x
16. When a drug increases the rate of drug metabolism of other drugs, the process is termed
,A. first-pass metabolism
B. enzyme induction
C. enzyme inhibition
D. enterohepatic cycling
E. microsomal inhibition - CORRECT ANSWER-B
17. The rate of drug absorption would be increased by which of the following?
A. drug ionization
B. water solubility
C. positively charged drug
D. negatively charged drug
E. lipid solubility - CORRECT ANSWER-E
18. Which factor of individual variation is dependent upon the patient's attitude toward
treatment?
A. weight
B. age
C. genetic variation
D. placebo effect
E. gender - CORRECT ANSWER-D
19. Which FDA pregnancy category would appear to be the safest for a developing fetus?
A. Category A
B. Category B
C. Category C
D. Category D
, E. Category X - CORRECT ANSWER-A
20. A 45-year-old female shop assistant is treated for heartburn with omeprazole. She notes
that the effect of a dose of omeprazole lasts much longer than that of a dose of the antacid drug
calcium carbonate she had previously taken. The active metabolite of omeprazole binds
covalently and irreversibly to a molecular structure involved in releasing protons into the gastric
juice. Drugs that modify their target structures through this mechanism are called
suicide substrates.
orphan drugs.
protein drugs.
competitive antagonists.
enantiomers. - CORRECT ANSWER-A
21. A 36-year-old male has been diagnosed with chronic myeloid leukemia. His oncologist
discusses treatment options with him. The patient is glad to hear that novel anticancer drugs
used to treat chronic myeloid leukemia have a much better risk-benefit ratio than older ones,
due to their improved selectivity. A major determinant for the selectivity of a given drug is
A) its target receptor ligand affinity.
B) its target receptor cell-type distribution.
C) its ionic interactions.
D) its hydrogen bonding.
E) its intrinsic activity. - CORRECT ANSWER-B
22. A 56-year-old man with chest pain is diagnosed with stable angina and treated with several
drugs including nitroglycerin. Every day he has to discontinue nitroglycerin for some hours to re-
establish reactivity of his body to the drug. The clinical observation of a rapidly decreasing
response to nitroglycerin after administration of just a few doses is called
idiosyncrasy.
tachyphylaxis.
