Test Bank for Lehninger Principles of
Biochemistry | Full Prep Guide | A+ Assured
• binding site . Answer: The crevice or pocket on a protein in which a
ligand binds.
• induced fit . Answer: A change in the conformation of an enzyme in
response to substrate binding that renders the enzyme catalytically
active; also denotes changes in the conformation of any macromolecule
in response to ligand binding, such that the binding site better conforms
to the shape of the ligand.
• hemoglobin . Answer: A heme protein in erythrocytes; functions in
oxygen transport.
• heme . Answer: The iron-porphyrin prosthetic group of heme proteins.
• porphyria . Answer: An inherited disease resulting from the lack of one
or more enzymes required to synthesize porphyrins.
• heme protein . Answer: A protein containing a heme as prosthetic
group.
• globins . Answer: A superfamily of heme-containing globular proteins,
involved in binding and/or transporting oxygen.
• equilibrium expression . Answer: The ratio of the concentrations of the
products over the reactants.
• association constant, Kₐ . Answer: A special case of the equilibrium
constant K, and is the inverse of the dissociation constant. It is
associated with the binding and unbinding reaction of receptor (R) and
ligand (L) molecules, which is formalized as: R + L ⇌ RL.
Biochemistry | Full Prep Guide | A+ Assured
• binding site . Answer: The crevice or pocket on a protein in which a
ligand binds.
• induced fit . Answer: A change in the conformation of an enzyme in
response to substrate binding that renders the enzyme catalytically
active; also denotes changes in the conformation of any macromolecule
in response to ligand binding, such that the binding site better conforms
to the shape of the ligand.
• hemoglobin . Answer: A heme protein in erythrocytes; functions in
oxygen transport.
• heme . Answer: The iron-porphyrin prosthetic group of heme proteins.
• porphyria . Answer: An inherited disease resulting from the lack of one
or more enzymes required to synthesize porphyrins.
• heme protein . Answer: A protein containing a heme as prosthetic
group.
• globins . Answer: A superfamily of heme-containing globular proteins,
involved in binding and/or transporting oxygen.
• equilibrium expression . Answer: The ratio of the concentrations of the
products over the reactants.
• association constant, Kₐ . Answer: A special case of the equilibrium
constant K, and is the inverse of the dissociation constant. It is
associated with the binding and unbinding reaction of receptor (R) and
ligand (L) molecules, which is formalized as: R + L ⇌ RL.
