EVOLVE PHARMACOLOGY
HESI PRACTICE
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,Question 1
A client who has been taking phenazopyridine (Pyridium) for symptoms of urethritis and cystitis comes to the clinic
because her urine is reddish-orange. Which question should the practical nurse ask to determine if the medication has
been effective?
A) How much water have you been drinking each day?
B) Does the urine color stain your toilet bowl or undergarments?
C) Have you had any relief from urinary pain, burning, or urgency?
D) Did your urine appear cloudy or have a foul odor on voiding?
Correct Answer
C) Have you had any relief from urinary pain, burning, or urgency?
Feedback:
Phenazopyridine, an over-the-counter urinary analgesic, acts on the mucosa of the urinary tract to relieve urinary
pain, burning, itching, or urgency (C) associated with urethritis and cystitis. Although determining if the client is
forcing fluids (A), experiencing staining from Pyridium's side effect (B), or having signs of a urinary infection (D) are
worthwhile assessments, the therapeutic response of Pyridium is related to urinary discomforts only.
Question 2
A male client who has been receiving an antineoplastic drug has developed thrombocytopenia. What instructions
should the practical nurse (PN) reinforce?
A) Use suppository form of drugs.
B) Avoid large public gatherings.
C) Rise slowly when standing up.
D) Shave with an electric razor.
Correct Answer
D) Shave with an electric razor.
Feedback:
Thrombocytopenia is a common side effect of bone marrow depression caused by several antineoplastic agents. The
client is experiencing a low platelet count and should use an electric razor (D) to reduce his risk of bleeding. (A, B,
and C) are not indicated for a client who needs to implement thrombocytopenia precautions.
Question 3
The practical nurse (PN) is caring for a client who has been taking prednisone (Deltasone) daily for a year. Which
adverse effect should the PN document in the client's record?
A) Photosensitvity.
B) Weight gain.
C) Loss of hair.
D) Pale skin color.
Correct Answer
B) Weight gain.
Feedback:
Long term use of prednisone causes fluid retention and redistribution of fat deposition. Weight gain (B) and moon
face reflect adverse effects of long-term prednisone use and should be documented. (A, C, and D) do not occur with
treatment using prednisone.
Trusted by thousands of students and professionals worldwide Page 2 of 22
, Question 4
A female client with recurring headaches tells the practical nurse (PN) that she has been taking at least 4 grams of
acetaminophen a day. Which laboratory studies should the PN review for this client?
A) Creatinine clearance.
B) Hepatic enzymes.
C) Coagulation values.
D) Arterial blood gases.
Correct Answer
B) Hepatic enzymes.
Feedback:
Liver toxicity can occur when doses of acetaminophen exceed 4 grams a day, resulting in an elevation in hepatic
enzyme values (B). (A, C, and D) do not reveal findings related to acetaminophen toxicity.
Question 5
A client receives a prescription for an oral opioid analgesic for post-operative pain. Which adverse effect should the
practical nurse (PN) monitor for with the client?
A) Constipation.
B) Photosensitivity.
C) Decreased heart rate.
D) Frequent urination.
Correct Answer
A) Constipation.
Feedback:
Opioid analgesics slow peristalsis, which leads to constipation (A), a common side effect of opiates. (B, C, and D) are
not associated with opioid analgesics.
Question 6
Which action should the practical nurse implement when administering a buccal medication?
A) Encourage the client to swallow.
B) Administer water with medication.
C) Ensure the medication is positioned under the tongue.
D) Place the medication between the upper molar teeth and cheek.
Correct Answer
D) Place the medication between the upper molar teeth and cheek.
Feedback:
Buccal medications are placed between the upper molar teeth and the cheek (D) for absorption by the capillaries of
the oral mucosa. The client should be cautioned against swallowing, not (A). Buccal medications are not
administered with water (B). (C) describes sublingual administration.
Trusted by thousands of students and professionals worldwide Page 3 of 22
HESI PRACTICE
60+ (Latest 2025-2026 Edition) 100%
Verified Q&A + Answer Key Solutions
100% Guarantee Pass
This Exam contains: Evolve Pharmacology hesi
✓ practice
✓ 100% Accurate Questions and Answers
✓ 100% Guarantee Pass - Verified by Experts
✓ Each Question Includes The Correct Answer
✓ Expert-Verified
Trusted by thousands of students and professionals worldwide Page 1 of 22
,Question 1
A client who has been taking phenazopyridine (Pyridium) for symptoms of urethritis and cystitis comes to the clinic
because her urine is reddish-orange. Which question should the practical nurse ask to determine if the medication has
been effective?
A) How much water have you been drinking each day?
B) Does the urine color stain your toilet bowl or undergarments?
C) Have you had any relief from urinary pain, burning, or urgency?
D) Did your urine appear cloudy or have a foul odor on voiding?
Correct Answer
C) Have you had any relief from urinary pain, burning, or urgency?
Feedback:
Phenazopyridine, an over-the-counter urinary analgesic, acts on the mucosa of the urinary tract to relieve urinary
pain, burning, itching, or urgency (C) associated with urethritis and cystitis. Although determining if the client is
forcing fluids (A), experiencing staining from Pyridium's side effect (B), or having signs of a urinary infection (D) are
worthwhile assessments, the therapeutic response of Pyridium is related to urinary discomforts only.
Question 2
A male client who has been receiving an antineoplastic drug has developed thrombocytopenia. What instructions
should the practical nurse (PN) reinforce?
A) Use suppository form of drugs.
B) Avoid large public gatherings.
C) Rise slowly when standing up.
D) Shave with an electric razor.
Correct Answer
D) Shave with an electric razor.
Feedback:
Thrombocytopenia is a common side effect of bone marrow depression caused by several antineoplastic agents. The
client is experiencing a low platelet count and should use an electric razor (D) to reduce his risk of bleeding. (A, B,
and C) are not indicated for a client who needs to implement thrombocytopenia precautions.
Question 3
The practical nurse (PN) is caring for a client who has been taking prednisone (Deltasone) daily for a year. Which
adverse effect should the PN document in the client's record?
A) Photosensitvity.
B) Weight gain.
C) Loss of hair.
D) Pale skin color.
Correct Answer
B) Weight gain.
Feedback:
Long term use of prednisone causes fluid retention and redistribution of fat deposition. Weight gain (B) and moon
face reflect adverse effects of long-term prednisone use and should be documented. (A, C, and D) do not occur with
treatment using prednisone.
Trusted by thousands of students and professionals worldwide Page 2 of 22
, Question 4
A female client with recurring headaches tells the practical nurse (PN) that she has been taking at least 4 grams of
acetaminophen a day. Which laboratory studies should the PN review for this client?
A) Creatinine clearance.
B) Hepatic enzymes.
C) Coagulation values.
D) Arterial blood gases.
Correct Answer
B) Hepatic enzymes.
Feedback:
Liver toxicity can occur when doses of acetaminophen exceed 4 grams a day, resulting in an elevation in hepatic
enzyme values (B). (A, C, and D) do not reveal findings related to acetaminophen toxicity.
Question 5
A client receives a prescription for an oral opioid analgesic for post-operative pain. Which adverse effect should the
practical nurse (PN) monitor for with the client?
A) Constipation.
B) Photosensitivity.
C) Decreased heart rate.
D) Frequent urination.
Correct Answer
A) Constipation.
Feedback:
Opioid analgesics slow peristalsis, which leads to constipation (A), a common side effect of opiates. (B, C, and D) are
not associated with opioid analgesics.
Question 6
Which action should the practical nurse implement when administering a buccal medication?
A) Encourage the client to swallow.
B) Administer water with medication.
C) Ensure the medication is positioned under the tongue.
D) Place the medication between the upper molar teeth and cheek.
Correct Answer
D) Place the medication between the upper molar teeth and cheek.
Feedback:
Buccal medications are placed between the upper molar teeth and the cheek (D) for absorption by the capillaries of
the oral mucosa. The client should be cautioned against swallowing, not (A). Buccal medications are not
administered with water (B). (C) describes sublingual administration.
Trusted by thousands of students and professionals worldwide Page 3 of 22
