Page 1 of 822
TEST BANK m
Katzung's Basic and Clinical Pharm
m m m m
acology, 16th Edition
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by Todd W. Vanderah, Chapters 1 - 66
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Katzung's Basic and Clinical Pharmacology
, Page 2 of 822
Table of Contents
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1.mIntroduction:mThemNaturemofmDrugsm&mDrugmDevelopmentm&mRegulation
2.mDrugmReceptorsm&mPharmacodynamics
3.mPharmacokineticsm&mPharmacodynamics:mRationalmDosingm&mthemTimemCoursemofmDrugmAction
4.mDrugmBiotransformation
5.mPharmacogenomics
6.mIntroductionmtomAutonomicmPharmacology
7.mCholinoceptor-Activatingm&mCholinesterase-InhibitingmDrugs
8.mCholinoceptor-BlockingmDrugs
9.mAdrenoceptormAgonistsm&mSympathomimeticmDrugs
10.mAdrenoceptormAntagonistmDrugs
11.mAntihypertensivemAgents
12.mVasodilatorsm&mthemTreatmentmofmAnginamPectoris
13.mDrugsmUsedminmHeartmFailure
14.mAgentsmUsedminmCardiacmArrhythmias
15.mDiureticmAgents
16.mHistamine,mSerotonin,m&mthemErgotmAlkaloids
17.mVasoactivemPeptides
18.mThemEicosanoids:mProstaglandins,mThromboxanes,mLeukotrienes,m&mRelatedmCompounds
19.mNitricmOxide
20.mDrugsmUsedminmAsthma
21.mIntroductionmtomthemPharmacologymofmCNSmDrugs
22.mSedative-HypnoticmDrugs
23.mThemAlcohols
24.mAntiseizuremDrugs
25.mGeneralmAnesthetics
26.mLocalmAnesthetics
27.mSkeletalmMusclemRelaxants
28.mPharmacologicmManagementmofmParkinsonismm&mOthermMovementmDisorders
29.mAntipsychoticmAgentsm&mLithium
30.mAntidepressantmAgents
31.mOpioidmAgonistsm&mAntagonists
32.mDrugsmofmAbuse
33.mAgentsmUsedminmCytopenias;mHematopoieticmGrowthmFactors
34.mDrugsmUsedminmDisordersmofmCoagulation
35.mAgentsmUsedminmDyslipidemia
36.mNonsteroidalmAnti-InflammatorymDrugs,mDisease-
Katzung's Basic and Clinical Pharmacology
, Page 3 of 822
ModifyingmAntirheumaticmDrugs,mNonopioidmAnalgesics,m&mDrugsmUsedminmGout
37.mHypothalamicm&mPituitarymHormones
38.mThyroidm&mAntithyroidmDrugs
39.mAdrenocorticosteroidsm&mAdrenocorticalmAntagonists
40.mThemGonadalmHormonesm&mInhibitors
41.mPancreaticmHormonesm&mAntidiabeticmDrugs
42.mAgentsmThatmAffectmBonemMineralmHomeostasis
43.mBeta-Lactamm&mOthermCellmWall-m&mMembrane-ActivemAntibiotics
44.mTetracyclines,mMacrolides,mClindamycin,mChloramphenicol,mStreptogramins,m&mOxazolidinones
45.mAminoglycosidesm&mSpectinomycin
46.mSulfonamides,mTrimethoprim,m&mQuinolones
47.mAntimycobacterialmDrugs
48.mAntifungalmAgents
49.mAntiviralmAgents
50.mMiscellaneousmAntimicrobialmAgents;mDisinfectants,mAntiseptics,m&mSterilants
51.mClinicalmUsemofmAntimicrobialmAgents
52.mAntiprotozoalmDrugs
53.mClinicalmPharmacologymofmthemAntihelminthicmDrugs
54.mCancermChemotherapy
55.mImmunopharmacology
56.mIntroductionmtomToxicology:mOccupationalm&mEnvironmental
57.mHeavymMetalmIntoxicationm&mChelators
58.mManagementmofmthemPoisonedmPatient
59.mSpecialmAspectsmofmPerinatalm&mPediatricmPharmacology
60.mSpecialmAspectsmofmGeriatricmPharmacology
61.mDermatologicmPharmacology
62.mDrugsmUsedminmthemTreatmentmofmGastrointestinalmDiseases
63.mTherapeuticm&mToxicmPotentialmofmOver-the-CountermAgents
64.mDietarymSupplementsm&mHerbalmMedications
65.mRationalmPrescribingm&mPrescriptionmWriting
66.mImportantmDrugmInteractionsm&mTheirmMechanismsm
Katzung's Basic and Clinical Pharmacology
, Page 4 of 822
Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
m m m m m m m m m m m
1.
Amnursemworkingminmradiologymadministersmiodinemtomampatientmwhomismhav
ingmamcomputedmtomographym(CT)mscan.mThemnursemworkingmonmthemoncolog
ymunitmadministersmchemotherapymtompatientsmwhomhavemcancer.mAtmthemPubli
cmHealthmDepartment,mamnursemadministersmammeasles-mumps-
rubellam(MMR)mvaccinemtomam14-month-
oldmchildmasmamroutinemimmunization.mWhichmbranchmofmpharmacologymbestmd
escribesmthemactionsmofmallmthreem nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
ANSWER: B
Feedback:
Pharmacologymismthemstudymofmthembiologicmeffectsmofmchemicals.mNursesmarem
involvedmwithmclinicalmpharmacologymormpharmacotherapeutics,mwhichmismamb
ranchmofmpharmacologymthatmdealsmwithmthemusesmofmdrugsmtomtreat,mprevent,ma
ndmdiagnosemdisease.mThemradiologymnursemismadministeringmamdrugmtomhelpmdi
agnosemamdisease.mThemoncologymnursemismadministeringmamdrugmtomhelpmtreatm
amdisease.mPharmacoeconomicsmincludesmanymcostsminvolvedminmdrugm therapy.
Pharmacodynamicsminvolvesmhowmamdrugmaffectsmthembodyma
ndmpharmacokineticsmismhowmthembodymactsmonmthembody.
2.
Amphysicianmhasmorderedmintramuscularm(IM)minjectionsmofmmorphine,mamna
rcotic,meverym4mhoursmasmneededmformpainminmammotormvehiclemaccidentmvictim
.mThemnursemismawaremthismdrugmhasmamhighmabusempotential.mUndermwhatmcate
gorymwouldmmorphinembemclassified?
A) SchedulemI
B) SchedulemII
Katzung's Basic and Clinical Pharmacology
TEST BANK m
Katzung's Basic and Clinical Pharm
m m m m
acology, 16th Edition
m m m
by Todd W. Vanderah, Chapters 1 - 66
m m m m m m m m
Katzung's Basic and Clinical Pharmacology
, Page 2 of 822
Table of Contents
m m
1.mIntroduction:mThemNaturemofmDrugsm&mDrugmDevelopmentm&mRegulation
2.mDrugmReceptorsm&mPharmacodynamics
3.mPharmacokineticsm&mPharmacodynamics:mRationalmDosingm&mthemTimemCoursemofmDrugmAction
4.mDrugmBiotransformation
5.mPharmacogenomics
6.mIntroductionmtomAutonomicmPharmacology
7.mCholinoceptor-Activatingm&mCholinesterase-InhibitingmDrugs
8.mCholinoceptor-BlockingmDrugs
9.mAdrenoceptormAgonistsm&mSympathomimeticmDrugs
10.mAdrenoceptormAntagonistmDrugs
11.mAntihypertensivemAgents
12.mVasodilatorsm&mthemTreatmentmofmAnginamPectoris
13.mDrugsmUsedminmHeartmFailure
14.mAgentsmUsedminmCardiacmArrhythmias
15.mDiureticmAgents
16.mHistamine,mSerotonin,m&mthemErgotmAlkaloids
17.mVasoactivemPeptides
18.mThemEicosanoids:mProstaglandins,mThromboxanes,mLeukotrienes,m&mRelatedmCompounds
19.mNitricmOxide
20.mDrugsmUsedminmAsthma
21.mIntroductionmtomthemPharmacologymofmCNSmDrugs
22.mSedative-HypnoticmDrugs
23.mThemAlcohols
24.mAntiseizuremDrugs
25.mGeneralmAnesthetics
26.mLocalmAnesthetics
27.mSkeletalmMusclemRelaxants
28.mPharmacologicmManagementmofmParkinsonismm&mOthermMovementmDisorders
29.mAntipsychoticmAgentsm&mLithium
30.mAntidepressantmAgents
31.mOpioidmAgonistsm&mAntagonists
32.mDrugsmofmAbuse
33.mAgentsmUsedminmCytopenias;mHematopoieticmGrowthmFactors
34.mDrugsmUsedminmDisordersmofmCoagulation
35.mAgentsmUsedminmDyslipidemia
36.mNonsteroidalmAnti-InflammatorymDrugs,mDisease-
Katzung's Basic and Clinical Pharmacology
, Page 3 of 822
ModifyingmAntirheumaticmDrugs,mNonopioidmAnalgesics,m&mDrugsmUsedminmGout
37.mHypothalamicm&mPituitarymHormones
38.mThyroidm&mAntithyroidmDrugs
39.mAdrenocorticosteroidsm&mAdrenocorticalmAntagonists
40.mThemGonadalmHormonesm&mInhibitors
41.mPancreaticmHormonesm&mAntidiabeticmDrugs
42.mAgentsmThatmAffectmBonemMineralmHomeostasis
43.mBeta-Lactamm&mOthermCellmWall-m&mMembrane-ActivemAntibiotics
44.mTetracyclines,mMacrolides,mClindamycin,mChloramphenicol,mStreptogramins,m&mOxazolidinones
45.mAminoglycosidesm&mSpectinomycin
46.mSulfonamides,mTrimethoprim,m&mQuinolones
47.mAntimycobacterialmDrugs
48.mAntifungalmAgents
49.mAntiviralmAgents
50.mMiscellaneousmAntimicrobialmAgents;mDisinfectants,mAntiseptics,m&mSterilants
51.mClinicalmUsemofmAntimicrobialmAgents
52.mAntiprotozoalmDrugs
53.mClinicalmPharmacologymofmthemAntihelminthicmDrugs
54.mCancermChemotherapy
55.mImmunopharmacology
56.mIntroductionmtomToxicology:mOccupationalm&mEnvironmental
57.mHeavymMetalmIntoxicationm&mChelators
58.mManagementmofmthemPoisonedmPatient
59.mSpecialmAspectsmofmPerinatalm&mPediatricmPharmacology
60.mSpecialmAspectsmofmGeriatricmPharmacology
61.mDermatologicmPharmacology
62.mDrugsmUsedminmthemTreatmentmofmGastrointestinalmDiseases
63.mTherapeuticm&mToxicmPotentialmofmOver-the-CountermAgents
64.mDietarymSupplementsm&mHerbalmMedications
65.mRationalmPrescribingm&mPrescriptionmWriting
66.mImportantmDrugmInteractionsm&mTheirmMechanismsm
Katzung's Basic and Clinical Pharmacology
, Page 4 of 822
Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
m m m m m m m m m m m
1.
Amnursemworkingminmradiologymadministersmiodinemtomampatientmwhomismhav
ingmamcomputedmtomographym(CT)mscan.mThemnursemworkingmonmthemoncolog
ymunitmadministersmchemotherapymtompatientsmwhomhavemcancer.mAtmthemPubli
cmHealthmDepartment,mamnursemadministersmammeasles-mumps-
rubellam(MMR)mvaccinemtomam14-month-
oldmchildmasmamroutinemimmunization.mWhichmbranchmofmpharmacologymbestmd
escribesmthemactionsmofmallmthreem nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
ANSWER: B
Feedback:
Pharmacologymismthemstudymofmthembiologicmeffectsmofmchemicals.mNursesmarem
involvedmwithmclinicalmpharmacologymormpharmacotherapeutics,mwhichmismamb
ranchmofmpharmacologymthatmdealsmwithmthemusesmofmdrugsmtomtreat,mprevent,ma
ndmdiagnosemdisease.mThemradiologymnursemismadministeringmamdrugmtomhelpmdi
agnosemamdisease.mThemoncologymnursemismadministeringmamdrugmtomhelpmtreatm
amdisease.mPharmacoeconomicsmincludesmanymcostsminvolvedminmdrugm therapy.
Pharmacodynamicsminvolvesmhowmamdrugmaffectsmthembodyma
ndmpharmacokineticsmismhowmthembodymactsmonmthembody.
2.
Amphysicianmhasmorderedmintramuscularm(IM)minjectionsmofmmorphine,mamna
rcotic,meverym4mhoursmasmneededmformpainminmammotormvehiclemaccidentmvictim
.mThemnursemismawaremthismdrugmhasmamhighmabusempotential.mUndermwhatmcate
gorymwouldmmorphinembemclassified?
A) SchedulemI
B) SchedulemII
Katzung's Basic and Clinical Pharmacology
