PHARMACOLOGY HESI V2 (NCLEX-PN) NEWEST 2026
ACTUAL EXAM TEST BANK| HESI PN
PHARMACOLOGY EXAM WITH COMPLETE 300 REAL
EXAM QUESTIONS AND CORRECT DETAILED
ANSWERS (VERIFIED ANSWERS) ALREADY GRADED
A+ (MOST RECENT!!)
The client with squamous cell carcinoma of the larynx is receiving
bleomycin intravenously. The nurse caring for the client anticipates that
which diagnostic study will be prescribed?
1. Echocardiography
2. Electrocardiography
3. Cervical radiography
4. Pulmonary function studies - Correct Answer - 4. Pulmonary function
studies
Bleomycin is an antineoplastic medication (Chemotheraputic Agents)
that can cause interstitial pneumonitis, which can progress to pulmonary
fibrosis. Pulmonary function studies along with hematological, hepatic,
and renal function tests need to be monitored. The nurse needs to
monitor lung sounds for dyspnea and crackles, which indicate
pulmonary toxicity. The medication needs to be discontinued
immediately if pulmonary toxicity occurs. Options 1, 2, and 3 are
unrelated to the specific use of this medication.
The client with acute myelocytic leukemia is being treated with busulfan
(Myleran). Which laboratory value would the nurse specifically monitor
during treatment with this medication?
1. Clotting time
pg. 1
,2. Uric acid level
3. Potassium level
4. Blood glucose level - Correct Answer - 2. Uric acid level
Busulfan (Myleran) can cause an increase in the uric acid level.
Hyperuricemia can produce uric acid nephropathy, renal stones, and
acute renal failure. Options 1, 3, and 4 are not specifically related to this
medication.
The client with small cell lung cancer is being treated with etoposide
(VePesid). The nurse who is assisting in caring for the client during its
administration understands that which side effect is specifically
associated with this medication?
1. Alopecia
2. Chest pain
3. Pulmonary fibrosis
4. Orthostatic hypotension - Correct Answer - 4. Orthostatic
hypotension
A side effect specific to etoposide is orthostatic hypotension. The client's
blood pressure is monitored during the infusion. Hair loss occurs with
nearly all the antineoplastic medications. Chest pain and pulmonary
fibrosis are unrelated to this medication.
The client with ovarian cancer is being treated with vincristine
(Oncovin). The nurse monitors the client, knowing that which of the
following indicates a side effect specific to this medication?
1. Diarrhea
2. Hair loss
3. Chest pain
pg. 2
,4. Numbness and tingling in the fingers and toes - Correct Answer - 4.
Numbness and tingling in the fingers and toes
A side effect specific to vincristine is peripheral neuropathy, which
occurs in almost every client. Peripheral neuropathy can be manifested
as numbness and tingling in the fingers and toes. Depression of the
Achilles tendon reflex may be the first clinical sign indicating peripheral
neuropathy. Constipation rather than diarrhea is most likely to occur
with this medication, although diarrhea may occur occasionally. Hair
loss occurs with nearly all the antineoplastic medications. Chest pain is
unrelated to this medication.
The nurse is reviewing the history and physical examination of a client
who will be receiving asparaginase (Elspar), an antineoplastic agent. The
nurse consults with the registered nurse regarding the administration of
the medication if which of the following is documented in the client's
history?
1. Pancreatitis
2. Diabetes mellitus
3. Myocardial infarction
4. Chronic obstructive pulmonary disease - Correct Answer - 1.
Pancreatitis
Asparaginase (Elspar) is contraindicated if hypersensitivity exists, in
pancreatitis, or if the client has a history of pancreatitis. The medication
impairs pancreatic function and pancreatic function tests should be
performed before therapy begins and when a week or more has elapsed
between administration of the doses. The client needs to be monitored
for signs of pancreatitis, which include nausea, vomiting, and abdominal
pain. The conditions noted in options 2, 3, and 4 are not contraindicated
with this medication.
pg. 3
, Tamoxifen is prescribed for the client with metastatic breast carcinoma.
The nurse understands that the primary action of this medication is to:
1. Increase DNA and RNA synthesis.
2. Promote the biosynthesis of nucleic acids.
3. Increase estrogen concentration and estrogen response.
4. Compete with estradiol for binding to estrogen in tissues containing
high concentrations of receptors. - Correct Answer - 4. Compete with
estradiol for binding to estrogen in tissues containing high
concentrations of receptors.
Tamoxifen is an antineoplastic medication that competes with estradiol
for binding to estrogen in tissues containing high concentrations of
receptors. Tamoxifen is used to treat metastatic breast carcinoma in
women and men. Tamoxifen is also effective in delaying the recurrence
of cancer following mastectomy. Tamoxifen reduces DNA synthesis and
estrogen response.
The client with metastatic breast cancer is receiving tamoxifen. The
nurse specifically monitors which laboratory value while the client is
taking this medication?
1. Glucose level
2. Calcium level
3. Potassium level
4. Prothrombin time - Correct Answer - 2. Calcium level
Tamoxifen may increase calcium, cholesterol, and triglyceride levels.
Before the initiation of therapy, a complete blood count, platelet count,
and serum calcium levels should be assessed. These blood levels, along
with cholesterol and triglyceride levels, should be monitored
periodically during therapy. The nurse should assess for hypercalcemia
while the client is taking this medication. Signs of hypercalcemia
pg. 4
ACTUAL EXAM TEST BANK| HESI PN
PHARMACOLOGY EXAM WITH COMPLETE 300 REAL
EXAM QUESTIONS AND CORRECT DETAILED
ANSWERS (VERIFIED ANSWERS) ALREADY GRADED
A+ (MOST RECENT!!)
The client with squamous cell carcinoma of the larynx is receiving
bleomycin intravenously. The nurse caring for the client anticipates that
which diagnostic study will be prescribed?
1. Echocardiography
2. Electrocardiography
3. Cervical radiography
4. Pulmonary function studies - Correct Answer - 4. Pulmonary function
studies
Bleomycin is an antineoplastic medication (Chemotheraputic Agents)
that can cause interstitial pneumonitis, which can progress to pulmonary
fibrosis. Pulmonary function studies along with hematological, hepatic,
and renal function tests need to be monitored. The nurse needs to
monitor lung sounds for dyspnea and crackles, which indicate
pulmonary toxicity. The medication needs to be discontinued
immediately if pulmonary toxicity occurs. Options 1, 2, and 3 are
unrelated to the specific use of this medication.
The client with acute myelocytic leukemia is being treated with busulfan
(Myleran). Which laboratory value would the nurse specifically monitor
during treatment with this medication?
1. Clotting time
pg. 1
,2. Uric acid level
3. Potassium level
4. Blood glucose level - Correct Answer - 2. Uric acid level
Busulfan (Myleran) can cause an increase in the uric acid level.
Hyperuricemia can produce uric acid nephropathy, renal stones, and
acute renal failure. Options 1, 3, and 4 are not specifically related to this
medication.
The client with small cell lung cancer is being treated with etoposide
(VePesid). The nurse who is assisting in caring for the client during its
administration understands that which side effect is specifically
associated with this medication?
1. Alopecia
2. Chest pain
3. Pulmonary fibrosis
4. Orthostatic hypotension - Correct Answer - 4. Orthostatic
hypotension
A side effect specific to etoposide is orthostatic hypotension. The client's
blood pressure is monitored during the infusion. Hair loss occurs with
nearly all the antineoplastic medications. Chest pain and pulmonary
fibrosis are unrelated to this medication.
The client with ovarian cancer is being treated with vincristine
(Oncovin). The nurse monitors the client, knowing that which of the
following indicates a side effect specific to this medication?
1. Diarrhea
2. Hair loss
3. Chest pain
pg. 2
,4. Numbness and tingling in the fingers and toes - Correct Answer - 4.
Numbness and tingling in the fingers and toes
A side effect specific to vincristine is peripheral neuropathy, which
occurs in almost every client. Peripheral neuropathy can be manifested
as numbness and tingling in the fingers and toes. Depression of the
Achilles tendon reflex may be the first clinical sign indicating peripheral
neuropathy. Constipation rather than diarrhea is most likely to occur
with this medication, although diarrhea may occur occasionally. Hair
loss occurs with nearly all the antineoplastic medications. Chest pain is
unrelated to this medication.
The nurse is reviewing the history and physical examination of a client
who will be receiving asparaginase (Elspar), an antineoplastic agent. The
nurse consults with the registered nurse regarding the administration of
the medication if which of the following is documented in the client's
history?
1. Pancreatitis
2. Diabetes mellitus
3. Myocardial infarction
4. Chronic obstructive pulmonary disease - Correct Answer - 1.
Pancreatitis
Asparaginase (Elspar) is contraindicated if hypersensitivity exists, in
pancreatitis, or if the client has a history of pancreatitis. The medication
impairs pancreatic function and pancreatic function tests should be
performed before therapy begins and when a week or more has elapsed
between administration of the doses. The client needs to be monitored
for signs of pancreatitis, which include nausea, vomiting, and abdominal
pain. The conditions noted in options 2, 3, and 4 are not contraindicated
with this medication.
pg. 3
, Tamoxifen is prescribed for the client with metastatic breast carcinoma.
The nurse understands that the primary action of this medication is to:
1. Increase DNA and RNA synthesis.
2. Promote the biosynthesis of nucleic acids.
3. Increase estrogen concentration and estrogen response.
4. Compete with estradiol for binding to estrogen in tissues containing
high concentrations of receptors. - Correct Answer - 4. Compete with
estradiol for binding to estrogen in tissues containing high
concentrations of receptors.
Tamoxifen is an antineoplastic medication that competes with estradiol
for binding to estrogen in tissues containing high concentrations of
receptors. Tamoxifen is used to treat metastatic breast carcinoma in
women and men. Tamoxifen is also effective in delaying the recurrence
of cancer following mastectomy. Tamoxifen reduces DNA synthesis and
estrogen response.
The client with metastatic breast cancer is receiving tamoxifen. The
nurse specifically monitors which laboratory value while the client is
taking this medication?
1. Glucose level
2. Calcium level
3. Potassium level
4. Prothrombin time - Correct Answer - 2. Calcium level
Tamoxifen may increase calcium, cholesterol, and triglyceride levels.
Before the initiation of therapy, a complete blood count, platelet count,
and serum calcium levels should be assessed. These blood levels, along
with cholesterol and triglyceride levels, should be monitored
periodically during therapy. The nurse should assess for hypercalcemia
while the client is taking this medication. Signs of hypercalcemia
pg. 4
