, McCance & Huether’s Pathophysiology: The Biologic Basis for Disease in
Adults and Children 10th Edition
by Julia Rogers DNP APRN CNS FNP-BC FAANP (Author)
Table of contents
Chapter 1: Cellular Biology
Chapter 2: Altered Cellular and Tissue Biology
Chapter 3: The Cellular Environment: Fluids and Electrolytes, Acids and Bases
Chapter 4: Genes and Genetic Diseases
Chapter 5: Genes, Environment-Lifestyle, and Common Diseases
Chapter 6: Epigenetics and Disease
Chapter 7: Innate Immunity: Inflammation
Chapter 8: Adaptive Immunity
Chapter 9: Alterations in Immunity and Inflammation
Chapter 10: Infection
Chapter 11: Stress and Disease
Chapter 12: Cancer Biology
Chapter 13: Cancer Epidemiology
Chapter 14: Cancer in Children
Chapter 15: Structure and Function of the Neurologic System
Chapter 16: Pain, Temperature Regulation, Sleep, and Sensory Function
Chapter 17: Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function
Chapter 18: Disorders of the Central and Peripheral Nervous Systems and the Neuromuscular Junction
Chapter 19: Neurobiology of Schizophrenia, Mood Disorders, and Anxiety Disorders
Chapter 20: Alterations of Neurologic Function in Children
Chapter 21: Mechanisms of Hormonal Regulation
Chapter 22: Alterations of Hormonal Regulation
Chapter 23: Obesity and Disorders of Nutrition
,Chapter 24: Structure and Function of the Reproductive Systems
Chapter 25: Alterations of the Female Reproductive System
Chapter 26: Alterations of the Male Reproductive System
Chapter 27: Sexually Transmitted Infections
Chapter 28: Structure and Function of the Hematologic System
Chapter 29: Alterations of Erythrocyte Platelet, Hemostatic Function
Chapter 30: Alterations of Leukocyte, Lymphoid Function
Chapter 31: Alterations of Hematologic Function in Children
Chapter 32: Structure and Function of the Cardiovascular and Lymphatic Systems
Chapter 33: Alterations of Cardiovascular Function
Chapter 34: Alterations of Cardiovascular Function in Children
Chapter 35: Structure and Function of the Pulmonary System
Chapter 36: Alterations of Pulmonary Function
Chapter 37: Alterations of Pulmonary Function in Children
Chapter 38: Structure and Function of the Renal and Urologic Systems
Chapter 39: Alterations of Renal and Urinary Tract Function
Chapter 40: Alterations of Renal and Urinary Tract Function in Children
Chapter 41: Structure and Function of the Digestive System
Chapter 42: Alterations of Digestive Function
Chapter 43: Alterations of Digestive Function in Children
Chapter 44: Structure and Function of the Musculoskeletal System
Chapter 45: Alterations of Musculoskeletal Function
Chapter 46: Alterations of Musculoskeletal Function in Children
Chapter 47: Structure, Function, and Disorders of the Integument
Chapter 48: Alterations of the Integument in Children
Chapter 49: Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults
Chapter 50: Shock, Multiple Organ Dysfunction Syndrome, and Burns in Children
, Q. What is the sequence of steps in the development of a digestive enzyme by the pancreas
cells from the initial transcription to the release from the cell?
a. The enzyme is transcribed from DNA by RNA in the nucleus, proceeds to the
ribosome for synthesis, and is transported in a secretory vesicle to the cell
membrane.
b. The enzyme is transcribed from RNA by DNA in the nucleus, proceeds to the
lysosome for synthesis, and is transported in an encapsulated membrane to the
cell membrane.
c. The enzyme is transcribed by the mitochondria in the nucleus, proceeds to the
ribosome for synthesis, and is transported in a cytoskeleton to the cell
membrane.
d. The enzyme is transcribed from DNA by RNA in the nucleus, proceeds to the
Golgi complex for synthesis, and is transported in a cytosol to the cell membrane.
ANS: A
The enzyme is transcribed from DNA by RNA in the nucleus, proceeds to the ribosome
for synthesis, and is transported in a secretory vesicle to the cell membrane. The other
options do not correctly describe this process.
NURSINGTB.COM
PTS: 1 REF: Page 7 | Figure 1-5
Q. Which cell component is capable of cellular autodigestion when it is released during
cell injury?
a. Ribosome c. Smooth endoplasmic reticulum
b. Golgi complex d. Lysosomes
ANS: D
The lysosomal membrane acts as a protective shield between the powerful digestive
enzymes within the lysosome and the cytoplasm, preventing their leakage into the
cytoplasmic matrix. Disruption of the membrane by various treatments or cellular injury
leads to a release of the lysosomal enzymes, which can then react with their specific
substrates, causing cellular self-digestion. The other options do not correctly describe this
process.
PTS: 1 REF: Pages 7-8
Q. Which component of the cell prodNuUceRsSIhNyGdTroBg.CenOMperoxide (H2O2) by
using oxygen to remove hydrogen atoms from specific substrates in an oxidative
reaction?
a. Lysosomes c. Ribosomes
b. Peroxisomes d. Oxyhydrosomes
ANS: B
Peroxisomes are so named because they usually contain enzymes that use oxygen to
remove hydrogen atoms from specific substrates in an oxidative reaction that produces
H2O2, which is a powerful oxidant and potentially destructive if it accumulates or escapes
Adults and Children 10th Edition
by Julia Rogers DNP APRN CNS FNP-BC FAANP (Author)
Table of contents
Chapter 1: Cellular Biology
Chapter 2: Altered Cellular and Tissue Biology
Chapter 3: The Cellular Environment: Fluids and Electrolytes, Acids and Bases
Chapter 4: Genes and Genetic Diseases
Chapter 5: Genes, Environment-Lifestyle, and Common Diseases
Chapter 6: Epigenetics and Disease
Chapter 7: Innate Immunity: Inflammation
Chapter 8: Adaptive Immunity
Chapter 9: Alterations in Immunity and Inflammation
Chapter 10: Infection
Chapter 11: Stress and Disease
Chapter 12: Cancer Biology
Chapter 13: Cancer Epidemiology
Chapter 14: Cancer in Children
Chapter 15: Structure and Function of the Neurologic System
Chapter 16: Pain, Temperature Regulation, Sleep, and Sensory Function
Chapter 17: Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function
Chapter 18: Disorders of the Central and Peripheral Nervous Systems and the Neuromuscular Junction
Chapter 19: Neurobiology of Schizophrenia, Mood Disorders, and Anxiety Disorders
Chapter 20: Alterations of Neurologic Function in Children
Chapter 21: Mechanisms of Hormonal Regulation
Chapter 22: Alterations of Hormonal Regulation
Chapter 23: Obesity and Disorders of Nutrition
,Chapter 24: Structure and Function of the Reproductive Systems
Chapter 25: Alterations of the Female Reproductive System
Chapter 26: Alterations of the Male Reproductive System
Chapter 27: Sexually Transmitted Infections
Chapter 28: Structure and Function of the Hematologic System
Chapter 29: Alterations of Erythrocyte Platelet, Hemostatic Function
Chapter 30: Alterations of Leukocyte, Lymphoid Function
Chapter 31: Alterations of Hematologic Function in Children
Chapter 32: Structure and Function of the Cardiovascular and Lymphatic Systems
Chapter 33: Alterations of Cardiovascular Function
Chapter 34: Alterations of Cardiovascular Function in Children
Chapter 35: Structure and Function of the Pulmonary System
Chapter 36: Alterations of Pulmonary Function
Chapter 37: Alterations of Pulmonary Function in Children
Chapter 38: Structure and Function of the Renal and Urologic Systems
Chapter 39: Alterations of Renal and Urinary Tract Function
Chapter 40: Alterations of Renal and Urinary Tract Function in Children
Chapter 41: Structure and Function of the Digestive System
Chapter 42: Alterations of Digestive Function
Chapter 43: Alterations of Digestive Function in Children
Chapter 44: Structure and Function of the Musculoskeletal System
Chapter 45: Alterations of Musculoskeletal Function
Chapter 46: Alterations of Musculoskeletal Function in Children
Chapter 47: Structure, Function, and Disorders of the Integument
Chapter 48: Alterations of the Integument in Children
Chapter 49: Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults
Chapter 50: Shock, Multiple Organ Dysfunction Syndrome, and Burns in Children
, Q. What is the sequence of steps in the development of a digestive enzyme by the pancreas
cells from the initial transcription to the release from the cell?
a. The enzyme is transcribed from DNA by RNA in the nucleus, proceeds to the
ribosome for synthesis, and is transported in a secretory vesicle to the cell
membrane.
b. The enzyme is transcribed from RNA by DNA in the nucleus, proceeds to the
lysosome for synthesis, and is transported in an encapsulated membrane to the
cell membrane.
c. The enzyme is transcribed by the mitochondria in the nucleus, proceeds to the
ribosome for synthesis, and is transported in a cytoskeleton to the cell
membrane.
d. The enzyme is transcribed from DNA by RNA in the nucleus, proceeds to the
Golgi complex for synthesis, and is transported in a cytosol to the cell membrane.
ANS: A
The enzyme is transcribed from DNA by RNA in the nucleus, proceeds to the ribosome
for synthesis, and is transported in a secretory vesicle to the cell membrane. The other
options do not correctly describe this process.
NURSINGTB.COM
PTS: 1 REF: Page 7 | Figure 1-5
Q. Which cell component is capable of cellular autodigestion when it is released during
cell injury?
a. Ribosome c. Smooth endoplasmic reticulum
b. Golgi complex d. Lysosomes
ANS: D
The lysosomal membrane acts as a protective shield between the powerful digestive
enzymes within the lysosome and the cytoplasm, preventing their leakage into the
cytoplasmic matrix. Disruption of the membrane by various treatments or cellular injury
leads to a release of the lysosomal enzymes, which can then react with their specific
substrates, causing cellular self-digestion. The other options do not correctly describe this
process.
PTS: 1 REF: Pages 7-8
Q. Which component of the cell prodNuUceRsSIhNyGdTroBg.CenOMperoxide (H2O2) by
using oxygen to remove hydrogen atoms from specific substrates in an oxidative
reaction?
a. Lysosomes c. Ribosomes
b. Peroxisomes d. Oxyhydrosomes
ANS: B
Peroxisomes are so named because they usually contain enzymes that use oxygen to
remove hydrogen atoms from specific substrates in an oxidative reaction that produces
H2O2, which is a powerful oxidant and potentially destructive if it accumulates or escapes
