CNRN Practice Test Questions and Answers Updated 2026

CNRN Practice Test Questions and
Answers Updated 2026
AMpatientMwithMaMknownMseizureMdisorderMisMadmittedMtoMtheMhospitalMwithMaltered
MmentalMstatus.MHisMphenytoinM(Dilantin)MlevelMisM35.6.MWhatMisMtheMmostMappropriat
eMaction?M-
MAnswerMHoldMphenytoinMandMrecMheckMaMlevelMtheMnextMday;MaMnormalMlevelM10-
20Mmcg/mL.MSupratherapeuticMlevelsMcanMcauseMconfusion,Mnausea,Murticaria,Mnystagmus,
Mhypotension,MandMcardiacMarrhythmias.



WhichMofMtheMfollowingMareMsourcesMofManMembolicMstroke?M-
MAnswerMPatentMforamenMovale;MAMpatentMforamenMovaleM(PFO)MisMaMholeMbetween
MtheMleftMandMrightMatriaMofMtheMheart.MItMnormallyMclosesMshortlyMafterMbirth.MThis
MconditionMmayMcauseMtheMformationMofMclotsMwhichMcanMtravelMtoMtheMbrainMleadi
ngMtoMaMtransientMischemicMattackMorMstroke.MTx-
antiplateletMmedsMorMbloodMthinners.MHTN,MobesityMandMHDLMareMriskMfactorsMforMthr
omboticMstroke.



AMpatientMc/oMofMaMheadacheMforMtheMpastMseveralMwksMisMdxMwithMaMsubacuteMsu
bduralMhematoma.MWhichMofMtheMfollowingMisMnotManMappropriateMcourseMofMaction?
M-
MAnswerMAdministerMlevetiracetamM(Keppra);MAntiepilepticMdrugsMareMnotMindicatedMfor
MsubacuteMhemorrhagicMbrainMinjuries.MTheMgreatestMriskMofMseizureMisMinMtheMfirstMt
woMweeksMfollowingMtheMincident.MIfMnoMseizureMhasMoccurredMduringMthisMtimeMthen
MantiepilepticMdrugsMdoMnotMneedMtoMbeMprescribedMforMtheMpatient.



WhichMofMtheMfollowingMregardingMastrocytomasMisMNOTMcorrect?M-
MAnswerMGraceMIVMastrocytomasMareMbenign;MAstrocytomasMariseMfromMastrocytes,Mwhi
chMareMaMtypeMofMglialMcell;MtheyMareMtheMmostMcommonMglialMtumor.MSurgicalMrese
ctionMinMconjunctionMwithMchemotherapyMandMradiationMareMcommonMtreatments.MGrad
eMIMandMIIMareMgenerallyMbenignMslowMgrowingMtumorsMseenMinMchildren,MwhereasMg
radesMIIIMandMIVMareMmalignantMandMtypicallyMseenMinMadults.



AMptMisMdxMwithMamyotrophicMlateralMsclerosisM(ALS)MandMtheMpt'sMwifeMisMconcerne
dMabtMtheirMchildrenMdevelopingMthisMcondition.MWhichMofMtheMfollowingMisManMappro
priateMresponse?M-
MAnswerMItsMetiologyMisMunknown;MthisMneuromuscularMdegenerativeMdiseaseMoccursMat
MrandomMwithMnoMclearlyMassociatedMriskMfactors.MIndividualsMwithMthisMsporadicMform
MofMtheMdiseaseMdoMnotMhaveMaMfamilyMhistoryMofMALS,MandMtheirMfamilyMmembers
MnotMconsideredMtoMbeMatMincreasedMriskMforMdevelopingMit.MInMaMsmallMmajorityMof
McasesMoccurMwithMaMfamilyMhxMofMthisMdisease.MMultipleMgeneMmutationsMareMinvolv
edMwithMdevelopingMthisMcondition.

, AMptMpresentsMwithMunilateralMsharp,MthrobbingMHAMassociatedMwithMeyeMpainMandMw
atering.MWhatMisMtheMmostMlikelyMdx?M-
MAnswerMClusterMheadache;MdueMtoMunknownMetiology.MTheyMareMcharacterizedMbyMun
ilateralMsymptomsMthatMmayMinvolveMtheMeyeMonMtheMipsilateralMside.MTx-
triptanMdrugs,McalciumMchannelMblockers,MandMsteroids.



AMchildMisMbornMwithMdozensMofMcafe-au-
laitMspotsMandMaxillaryMfreckling.MWhatMisMtheMmostMlikelyMdx?M-
MAnswerMNeurofibromatosis;MoccursMd/tMaMgeneticMdefect,MwhichMcausesMtumorsMtoMa
riseMfromMnerveMcells.MComplicationsMthatMmayMoccurMfromMthisMdisorderMincludeMdea
fness,MHTN,Mseizures,Mhydrocephalus,Mscoliosis,MpathologicMfxs,Mkyphosis,MandMvisionMpro
blems.MCommonMsignsMandMsymptomsMincludeMlightMbrownMspotsMonMtheMskinMalledM
cafe-au-
laitMspots,MabnormalMdevelopmentMofMtheMspin,Mskull,MorMlongMbones,MfrecklingMinMth
eMareMofMtheMarmpitMorMtheMgroin.MandMdisturbancesMinMbalance.



AMchildMwithMspinalMbifidaMdevelopsMworseningMheadachesMandMvisualMproblems.MAnM
MRIMofMtheMbrainMrevealsMherniationMofMtheMbrainstemMandMlowerMpartMofMtheMcere
bellumMextendingMintoMtheMforamenMmagnum.MWhichMtypeMofMChiariMmalformationMdo
esMthisMconditionMdescribe?M-
MAnswerMTypeMII;MtheMmostMcommonMtypeMofMChiariMmalformation.MTypeMIMisMwhere
MtheMlowerMpartMofMtheMcerebellum,MbutMnotMtheMbrainstemMextendsMintoMtheMfora
menMmagnum.MTypeMIIIMisMwhereMpartMofMtheMcerebellumMandMtheMbrainstemMextend
MthroughMtheMforamenMmagnumMintoMtheMspinalMcordMcausingMsevereMneurologicMimp
airment.MChiariMmalformationMtypeMIVMisMnotMassociatedMwithMherniationMofMtheMbrain
MthroughMtheMforamenMmagnum;MitMinvolvesManMunderdevelopedMcerebellum.MThisMtyp
eMisMusuallyMfatalMinMinfancy.



WhichMofMtheMfollowingMisMtheMmostMcommonMpresentingMsymptomMforMChiariMmalfor
mation?M-
MAnswerMOccipitalMheadaches;McausedMbyMtheMherniationMofMtheMbrainMthroughMtheMs
kullMbase.MOtherMsignsMandMsymptomsMincludeMdiplopia,Mnystagmus,MvisualMchanges,Ma
ndMbalanceMdifficulties.



AMptMpresentingMwithMdysarthriaMandMlethargyMisMbeingMevaluatedMinMtheMERMforMpo
ssibleMstroke.MTheMptMhasMGlasgowMComaMScaleM(GCS)MofM12,MBPMofM150/72,Mpulse
MoxMofM96%MonMroomMair,MBGMofM43,MandMptMscoresMaM9MonMtheMNIHSS.MWhatM
isMtheMbestMnextMstepMinMintervention?M-
MAnswerMAdministerMD50;MifMtheMpt'sMneurologicalMexamMdoesn'tMimproveMonceMtheM
BGMnormalizes,MthenMobtainingMaMCTMofMtheMheadMwouldMbeMappropriate.MIfMtheMCT
MofMtheMheadMisMnegativeMthenMadministeringMtPAMwouldMbeMtheMnextMstepMifMther