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Nu 578 Unit 3 Exam (2026/2027) | 200 Advanced Nclex-Style Questions With Answers & Rationales | Guaranteed Pass Prep

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This NU 578 Unit 3 exam guide features 200 advanced NCLEX-style questions focused on fluid balance, electrolytes, acid-base disorders, and critical clinical decision-making. Each question includes detailed rationales to reinforce key nursing concepts and improve test-taking strategies. Designed for advanced nursing students, this resource mirrors real exam difficulty and question style. It is ideal for last-minute review or full exam simulation practice. Use this comprehensive guide to boost confidence and maximize your chances of passing on the first attempt.

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NU 578 UNIT 3 EXAM (2026/2027) | 200
ADVANCED NCLEX-STYLE QUESTIONS
WITH ANSWERS & RATIONALES |
GUARANTEED PASS PREP


NU 578 Unit 3 Exam Practice


1. Which lab value is most indicative of renal function?
A. Hemoglobin
B. Creatinine
C. Platelets
D. Sodium
Answer: B
Creatinine reflects kidney filtration ability.


2. A patient with elevated BUN and creatinine likely has:
A. Liver disease
B. Renal impairment
C. Infection
D. Dehydration only
Answer: B
Both values rise with kidney dysfunction.


3. Which electrolyte imbalance causes cardiac arrhythmias?
A. Sodium
B. Potassium
C. Calcium
D. Chloride
Answer: B
Potassium directly affects cardiac conduction.

,4. Hyperkalemia is defined as potassium above:
A. 3.5
B. 4.0
C. 5.0
D. 6.0
Answer: C
Normal range is ~3.5–5.0 mEq/L.


5. Hypokalemia may cause:
A. Bradycardia
B. Weakness
C. Hypertension
D. Fever
Answer: B
Low potassium affects muscle function.


6. Which condition causes metabolic acidosis?
A. Vomiting
B. Diarrhea
C. Hyperventilation
D. Antacids
Answer: B
Loss of bicarbonate through GI tract.


7. Respiratory alkalosis is caused by:
A. Hypoventilation
B. Hyperventilation
C. Renal failure
D. Diarrhea
Answer: B
Excess CO₂ loss increases pH.


8. Normal arterial pH is:
A. 6.8–7.0
B. 7.0–7.2

,C. 7.35–7.45
D. 7.5–8.0
Answer: C
Normal physiologic range.


9. Which condition leads to respiratory acidosis?
A. Hyperventilation
B. Hypoventilation
C. Diarrhea
D. Vomiting
Answer: B
CO₂ retention lowers pH.


10. Which ABG value reflects oxygenation?
A. pH
B. PaCO₂
C. PaO₂
D. HCO₃
Answer: C
Measures oxygen in arterial blood.


11. Which medication is used for hyperkalemia?
A. Insulin
B. Aspirin
C. Heparin
D. Ibuprofen
Answer: A
Insulin drives potassium into cells.


12. Calcium imbalance affects:
A. Vision
B. Bone and muscle
C. Hearing
D. Smell

, Answer: B
Essential for bone strength and muscle contraction.


13. Hyponatremia may cause:
A. Confusion
B. Hypertension
C. Fever
D. Pain
Answer: A
Low sodium affects neurological status.


14. Which IV fluid is isotonic?
A. D5W
B. NS (0.9%)
C. 0.45% NS
D. D10
Answer: B
Matches body fluid osmolarity.


15. Which fluid is hypotonic?
A. NS
B. D5W
C. 0.45% NS
D. LR
Answer: C
Dilutes extracellular fluid.


16. Which fluid is hypertonic?
A. NS
B. D5W
C. 3% saline
D. 0.45% NS
Answer: C
Draws fluid out of cells.

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