MICROBIOLOGY WGU OA 2026 EXPERT REVIEW
TEST PAPER FULL QUESTIONS GRADED A+
▶ Other off label medications for alcohol use disorder according to
Dynamed? Answer:Topiramate, gabapentin, baclofen
▶ Other off label medications for alcohol use disorder according to Stahl's?
Answer:Topiramate, ondansetron
▶ MOA of Naltrexone? Answer:Opioid Receptor Antagonist
▶ MOA of Acamprosate? Answer:- weak GABAa agonist
- weak NMDA antagonist
(does not prevent withdrawal symptoms)
▶ MOA of Disulfuram? Answer:inhibits enzyme (aldehyde dehydrogenase)
in the liver
▶ Bupropions role in alcohol use disorder? Answer:Can diminish cravings
for etoh, treat underlying anxiety/depression
▶ Safety Risk associated with bupropion and etoh? Answer:bupropion
increases the risk of seizures in those going through etoh withdrawal
▶ s/s ETOH intoxication? Answer:impaired fine motor control, impaired
judgement and coordination, ataxic gait, poor balance, lethargy, difficulty
sitting upright, difficulty with memory and sitting upright, N/V, coma in levels
300mg/dL and over with respiratory depression and death possible
▶ S/S of etoh withdrawal? Answer:Mild: insomnia, irritability, hand tremor
Moderate: autonomic hyperactivity (diaphoresis, tachycardia, HTN), fever
Severe: seizures (12-48 hours post consumption), hallucinations, Delirium
Tremens
▶ Delirium Tremens? Answer:48-96 hours after last etoh consumption
includes anxiety, anorexia, nausea/vomiting, psychomotor agitation
, ▶ Scale used to measure etoh withdrawal? Answer:CIWA
▶ CIWA assesses:? Answer:n/v, tremor, paroxysmall sweats, anxiety,
agitation, tactile disturbances, auditory disturbances, visual disturbances,
headaches, orientation
▶ CIWA scoring? Answer:<10=mild
10-15=moderate
>15=severe
▶ What medication is FDA approved for both opioid use disorder and
alcohol use disorder?? Answer:Naltrexone
▶ What routes of administration exist for Naltrexone? Answer:PO, monthly
injection (Vivitrol), implant
▶ What is the First Line medication in maintaining abstinence after alcohol
detoxification?? Answer:Acamprosate
▶ What medication can safely be used to treat alcohol use disorder in
patients who keep drinking alcohol?? Answer:Acamprosate
▶ What medication used to treat alcohol use disorder can be safely
administered to patients with hepatitis and/or liver disease?
Answer:Acamprosate
▶ What medication used to treat alcohol use disorder is contraindicated
with severe renal disease?? Answer:Acamprosate
▶ Aversion symptoms with Disulfuram? Answer:flushing, N/V, HA, vertigo,
SOB, hypotension, palpitation
▶ How long do you need to wait to administer antabuse?? Answer:Person
needs to be alcohol free for 12 hours
▶ Important Education for patients taking Disulfuram? Answer:Do not use
anything that contains alcohol: mouthwash, aftershave, perfumes, vinegar,
cough medicine for up to two weeks after last dose of disulfuram
TEST PAPER FULL QUESTIONS GRADED A+
▶ Other off label medications for alcohol use disorder according to
Dynamed? Answer:Topiramate, gabapentin, baclofen
▶ Other off label medications for alcohol use disorder according to Stahl's?
Answer:Topiramate, ondansetron
▶ MOA of Naltrexone? Answer:Opioid Receptor Antagonist
▶ MOA of Acamprosate? Answer:- weak GABAa agonist
- weak NMDA antagonist
(does not prevent withdrawal symptoms)
▶ MOA of Disulfuram? Answer:inhibits enzyme (aldehyde dehydrogenase)
in the liver
▶ Bupropions role in alcohol use disorder? Answer:Can diminish cravings
for etoh, treat underlying anxiety/depression
▶ Safety Risk associated with bupropion and etoh? Answer:bupropion
increases the risk of seizures in those going through etoh withdrawal
▶ s/s ETOH intoxication? Answer:impaired fine motor control, impaired
judgement and coordination, ataxic gait, poor balance, lethargy, difficulty
sitting upright, difficulty with memory and sitting upright, N/V, coma in levels
300mg/dL and over with respiratory depression and death possible
▶ S/S of etoh withdrawal? Answer:Mild: insomnia, irritability, hand tremor
Moderate: autonomic hyperactivity (diaphoresis, tachycardia, HTN), fever
Severe: seizures (12-48 hours post consumption), hallucinations, Delirium
Tremens
▶ Delirium Tremens? Answer:48-96 hours after last etoh consumption
includes anxiety, anorexia, nausea/vomiting, psychomotor agitation
, ▶ Scale used to measure etoh withdrawal? Answer:CIWA
▶ CIWA assesses:? Answer:n/v, tremor, paroxysmall sweats, anxiety,
agitation, tactile disturbances, auditory disturbances, visual disturbances,
headaches, orientation
▶ CIWA scoring? Answer:<10=mild
10-15=moderate
>15=severe
▶ What medication is FDA approved for both opioid use disorder and
alcohol use disorder?? Answer:Naltrexone
▶ What routes of administration exist for Naltrexone? Answer:PO, monthly
injection (Vivitrol), implant
▶ What is the First Line medication in maintaining abstinence after alcohol
detoxification?? Answer:Acamprosate
▶ What medication can safely be used to treat alcohol use disorder in
patients who keep drinking alcohol?? Answer:Acamprosate
▶ What medication used to treat alcohol use disorder can be safely
administered to patients with hepatitis and/or liver disease?
Answer:Acamprosate
▶ What medication used to treat alcohol use disorder is contraindicated
with severe renal disease?? Answer:Acamprosate
▶ Aversion symptoms with Disulfuram? Answer:flushing, N/V, HA, vertigo,
SOB, hypotension, palpitation
▶ How long do you need to wait to administer antabuse?? Answer:Person
needs to be alcohol free for 12 hours
▶ Important Education for patients taking Disulfuram? Answer:Do not use
anything that contains alcohol: mouthwash, aftershave, perfumes, vinegar,
cough medicine for up to two weeks after last dose of disulfuram
