Health Care Practice 2026
Main categories of pharmacological drugs used to treat hypertension -
>>>>>>ANSWER Diuretics
Adrenergic drugs
Vasodilators
Angiotensin-converting enzyme (ACE) inhibitors
Angiotensin receptor blockers (ARBs)
Calcium channel blockers
Direct renin inhibitors
All antihypertensive drugs have some vasodilatory action except for - >>>>>>ANSWER
Diuretics
Blood pressure is determined by - >>>>>>ANSWER the product of cardiac output and
systemic vascular resistance
cardiac output - >>>>>>ANSWER the amount of blood that is ejected from the left
ventricle
systemic vascular resistance - >>>>>>ANSWER resistance to blood flow determined by
the diameter of the blood vessel and the vascular musculature
All antihypertensives in some way affect - >>>>>>ANSWER cardiac output
Adrenergic antihypertensive drug category comprises five subcategories -
>>>>>>ANSWER -Adrenergic neuron blockers (central and peripheral)
-α2-receptor agonists (central)
-α1-receptor blockers (peripheral)
-β-receptor blockers (peripheral)
-Combination α1- and β-receptor blockers (peripheral).
Centrally acting adrenergic drugs work by stimulating - >>>>>>ANSWER -Alpha2-
adrenergic receptors in the brain
-Resulting in a lack of norepinephrine production, which reduces blood pressure
alpha 2-adrenergic receptors also affects the kidneys by reducing - >>>>>>ANSWER
the activity of renin
In the periphery, the α1-blockers results in - >>>>>>ANSWER -Dilating of arteries and
veins
-Urinary output will increase
B-Blockers antihypertensive effects - >>>>>>ANSWER -Reduction in secretion of renin
-Reduces peripheral vascular resistance
Adrenergic drugs, when given for hypertension is for - >>>>>>ANSWER severe heart
failure
Adrenergic drugs most common side effect - >>>>>>ANSWER orthostatic hypotension
What to look for in orthostatic hypotension? - >>>>>>ANSWER -Does the BP drop 20
points while standing up or changing position
-Does the heart rate go up 20 points
ACE inhibitor effects - >>>>>>ANSWER -Blocks activation of angiotensin 1, which
stops angiotensin 2 production
-Decreases systemic vascular resistance affecting preload
-Decreased BP