NURS 530 Advanced Pharmacology Module 1
Study online at https://quizlet.com/_1tz3se
1. Who grants the authority for Np's to apply for and receive a DEA number?: The
state that the Np is working in
2. Who ultimately has control over prescriptive privileges?: The state.
3. What federal agency registers individuals who may prescribe narcotics and
other controlled substances?: DEA (Drug Enforcement Agency)
4. What federal agency registers individuals who may prescribe narcotics and
other controlled substances? DEA (Drug Enforcement Agency): 1. drug regulation
2. prescribe, dispense, or administer
5. What are the 2 types of prescriptive authority permitted in nursing legisla-
tion?: 1. Dependent authority
2. Independent authority
6. Describe dependent authority?: Requires that the physician has ultimate authority through
counter-signature of scripts or a written agreement between the NP and the physician that outlines the need for chart
review, discussion, and oversight with the physician collaborator.
7. Describe independent authority?: It allows the NP to prescribe alone. It could still be restricted,for
example by excluding the prescribing of controlled substances or limiting the scripts to a certain drug formulary.
8. It allows the NP to prescribe alone. It could still be restricted,for example by
excluding the prescribing of controlled substances or limiting the scripts to a
certain drug formulary.: Master's prepared: Apply to the ISBN with proof of completion of graduation from
an accredited program, licenses, and collaborative agreements.
Bachelor's prepared: If you received a bachelor's degree rather than a graduate degree, you must submit proof of
current national certification, licenses, and collaborative agreements.
9. How do you apply for DEA license in the state of Indiana?: Must apply for a CSR
(Controlled Substance Registration) through the ISBN and once that is obtained then you can apply to the DEA for
the DEA license.
10. Does an APN have to be nationally certified to practice in the state of Indi-
ana?: No, unless you only have a BSN, then you must be certified nationally in the category that you intend to practice
in.
11. Pharmacokinetics: The movement of the drug through the body or what the body does to the drug.
Includes: absorption, distribution, metabolism, and elimination.
12. Pharmacodynamics: What the drug does to the body.
13. Absorption: Describes how the drug leaves its site of administration.
1/5
, NURS 530 Advanced Pharmacology Module 1
Study online at https://quizlet.com/_1tz3se
14. Bio-availability: Fraction of drug that reaches the circulation.
15. Therapeutic drug level: The minimal effective concentration of a drug.
16. If medication is free-floating or unbound what does this cause?: Toxicity
17. What affects all pharmacokinetic pathways?: Blood pressure
18. Why is protein so important in pharmacokinetics?: Protein (albumin) binding is how
medications are transported or distributed. Low albumin or protein could create an increased level of unbound
medication and toxicity.
19. Explain the absorption process?: Process occurs from the time the drug enters the body to the time
that it enters the bloodstream to be circulated.
20. What determines onset of action?: Rate of absorption.
21. What is the first-pass effect?: When drugs are given orally, absorbed from the GI tract, and carried
to the liver for metabolism via the portal circulation.
22. What are drug-related variables that affect pharmacokinetics?: The route, dose,
and frequency of the medication.
23. What are patient-related variables that affect pharmacokinetics?: Liver-metabo-
lism, kidney-elimination and metabolism, allergies, weight-lean vs fat, neuro status, respiratory status, gender,ethnicity,
previous meds, vital signs, age
24. Describe how pediatrics metabolize meds?: They are ultra-metabolizers. May need higher
doses because they metabolize the drug more quickly.
25. 2 ways that drugs are transported from the GI tract across cell membranes?-
: Passive diffusion and active transport
26. Bio-equivalence?: Means that 2 drugs contain the same active ingredients and are identical in strength or
concentration, dosage form, and route of administration and have essentially the same rate and extent of bio-availability.
27. How much bio-equivalence variability is allowed in generic drugs?: + or - 20% of
the proprietary drug.
28. What is an example of a drug should never be prescribed in the generic form
because of its narrow therapeutic window?: Lanoxin.
29. What drug characteristics affect drug absorption?: Formulation of the drug, concentration
of the drug, lipophilic drug formulations (more readily absorbable), Acidic drugs (become non-ionized in the stomach
and are diffused across the membranes).
30. What part of pharmacokinetics are affected by a change in acidity in the
stomach?: Absorption
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Study online at https://quizlet.com/_1tz3se
1. Who grants the authority for Np's to apply for and receive a DEA number?: The
state that the Np is working in
2. Who ultimately has control over prescriptive privileges?: The state.
3. What federal agency registers individuals who may prescribe narcotics and
other controlled substances?: DEA (Drug Enforcement Agency)
4. What federal agency registers individuals who may prescribe narcotics and
other controlled substances? DEA (Drug Enforcement Agency): 1. drug regulation
2. prescribe, dispense, or administer
5. What are the 2 types of prescriptive authority permitted in nursing legisla-
tion?: 1. Dependent authority
2. Independent authority
6. Describe dependent authority?: Requires that the physician has ultimate authority through
counter-signature of scripts or a written agreement between the NP and the physician that outlines the need for chart
review, discussion, and oversight with the physician collaborator.
7. Describe independent authority?: It allows the NP to prescribe alone. It could still be restricted,for
example by excluding the prescribing of controlled substances or limiting the scripts to a certain drug formulary.
8. It allows the NP to prescribe alone. It could still be restricted,for example by
excluding the prescribing of controlled substances or limiting the scripts to a
certain drug formulary.: Master's prepared: Apply to the ISBN with proof of completion of graduation from
an accredited program, licenses, and collaborative agreements.
Bachelor's prepared: If you received a bachelor's degree rather than a graduate degree, you must submit proof of
current national certification, licenses, and collaborative agreements.
9. How do you apply for DEA license in the state of Indiana?: Must apply for a CSR
(Controlled Substance Registration) through the ISBN and once that is obtained then you can apply to the DEA for
the DEA license.
10. Does an APN have to be nationally certified to practice in the state of Indi-
ana?: No, unless you only have a BSN, then you must be certified nationally in the category that you intend to practice
in.
11. Pharmacokinetics: The movement of the drug through the body or what the body does to the drug.
Includes: absorption, distribution, metabolism, and elimination.
12. Pharmacodynamics: What the drug does to the body.
13. Absorption: Describes how the drug leaves its site of administration.
1/5
, NURS 530 Advanced Pharmacology Module 1
Study online at https://quizlet.com/_1tz3se
14. Bio-availability: Fraction of drug that reaches the circulation.
15. Therapeutic drug level: The minimal effective concentration of a drug.
16. If medication is free-floating or unbound what does this cause?: Toxicity
17. What affects all pharmacokinetic pathways?: Blood pressure
18. Why is protein so important in pharmacokinetics?: Protein (albumin) binding is how
medications are transported or distributed. Low albumin or protein could create an increased level of unbound
medication and toxicity.
19. Explain the absorption process?: Process occurs from the time the drug enters the body to the time
that it enters the bloodstream to be circulated.
20. What determines onset of action?: Rate of absorption.
21. What is the first-pass effect?: When drugs are given orally, absorbed from the GI tract, and carried
to the liver for metabolism via the portal circulation.
22. What are drug-related variables that affect pharmacokinetics?: The route, dose,
and frequency of the medication.
23. What are patient-related variables that affect pharmacokinetics?: Liver-metabo-
lism, kidney-elimination and metabolism, allergies, weight-lean vs fat, neuro status, respiratory status, gender,ethnicity,
previous meds, vital signs, age
24. Describe how pediatrics metabolize meds?: They are ultra-metabolizers. May need higher
doses because they metabolize the drug more quickly.
25. 2 ways that drugs are transported from the GI tract across cell membranes?-
: Passive diffusion and active transport
26. Bio-equivalence?: Means that 2 drugs contain the same active ingredients and are identical in strength or
concentration, dosage form, and route of administration and have essentially the same rate and extent of bio-availability.
27. How much bio-equivalence variability is allowed in generic drugs?: + or - 20% of
the proprietary drug.
28. What is an example of a drug should never be prescribed in the generic form
because of its narrow therapeutic window?: Lanoxin.
29. What drug characteristics affect drug absorption?: Formulation of the drug, concentration
of the drug, lipophilic drug formulations (more readily absorbable), Acidic drugs (become non-ionized in the stomach
and are diffused across the membranes).
30. What part of pharmacokinetics are affected by a change in acidity in the
stomach?: Absorption
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