Advanced pharmacology for NP Exam 2
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1. Ray has been diagnosed with hypertension and it is determined that an
angiotensin-converting enzyme inhibitor is needed. Prior to prescribing this
drug, the nurse practitioner (NP) should assess for:: Decreased renal function
2. Angiotensin-converting enzyme (ACE) inhibitors are the drug of choice in
treating hypertension in diabetic patients because they:: All of the above:
Improve insulin sensitivity
Improve renal hemodynamics
Reduce the production of angiotensin II
3. A potentially life-threatening adverse response to an ACE inhibitor is an-
gioedema. Which of the following statements is true about this adverse re-
sponse?: Swelling of the tongue and hoarseness are the most common symptoms.
4. ACE inhibitors are useful in a variety of disorders. Which of the following
statements is true about both their usefulness in a particular disorder and the
reason for their use?: Both 1 and 2 are true:
1. They are useful to prevent stable angina because they decrease the thickening of vascular walls due to decreased
modified release.
2. They are useful to prevent heart failure because they reduce remodeling of injured myocardial tissues.
5. Despite good blood pressure control, an NP might change a patient's drug
from an ACE inhibitor to an angiotensin II receptor blocker (ARB) because the
ARB:: Does not produce a dry, hacking cough
6. While taking an ARB, patients need to avoid certain over-the-counter drugs
without irst consulting the provider because:: Both 1 and 2:
1. Cimetidine is metabolized by the CYP3A4 isoenzymes
2. Nonsteroidal anti-inflammatory drugs reduce prostaglandin levels
7. Laboratory monitoring for patients on ACE inhibitors or ARBs should include:-
: Serum creatinine levels with the drug dosage reduced for values greater than 2.5 mg/dL
8. Jacob has hypertension, for which a calcium channel blocker has been pre-
scribed. This drug helps control blood pressure because it:: Decreases the amount of
calcium inside the cell
9. Which of the following adverse effects may occur due to a dihydropyri-
dine-type calcium channel blocker?: Edema of the hands and feet
, Advanced pharmacology for NP Exam 2
Study online at https://quizlet.com/_8v3bwd
10. Patient teaching related to amlodipine includes:: Avoid grapefruit juice as it affects the
metabolism of this drug.
11. Vera, age 70, has isolated systolic hypertension. Calcium channel blocker
dosages for her should be:: Started at about half the usual dosage
12. Larry has heart failure, which is being treated with digoxin because it ex-
hibits:: Negative inotropism
13. Furosemide is added to a treatment regimen for heart failure that includes
digoxin. Monitoring for this combination includes:: Serum potassium
14. Which of the following create a higher risk for digoxin toxicity? Both the
cause and the reason for it must be correct.: Administration to older adults because of reduced
renal function
15. Serum digoxin levels are monitored for potential toxicity. Monitoring should
occur:: Because a reference point is needed to adjust dosage
16. Which of the following is true about procainamide and its dosing schedule?:
17. Rodrigo has been prescribed procainamide after a myocardial infarction. He
is monitored for dyspnea, jugular venous distention, and peripheral edema
because they may indicate:: Onset of congestive heart failure
18. Amiodarone has been prescribed in a patient with a supraventricular dys-
rhythmia. Patient teaching should include all of the following EXCEPT:: Take a hot
shower or bath if you feel dizzy.
19. The NP orders a thyroid panel for a patient on amiodarone. The patient
tells the NP that he does not have thyroid disease and wants to know why the
test has been ordered. Which is a correct response?: Amiodarone inhibits an enzyme that is
important in making thyroid hormone and can cause hypothyroidism.
20. Isosorbide dinitrate is prescribed for a patient with chronic stable angina.
This drug is administered twice daily, but the schedule is 7 a.m. and 2 p.m.
because:: Nitrate tolerance can develop.
21. Art is a 55-year-old smoker who has been diagnosed with angina and placed
on nitrates. He complains of headaches after using his nitrate. An appropriate
reply might be::
22. In teaching about the use of sublingual nitroglycerine, the patient should be
instructed:: To place one tablet under the tongue if chest pain occurs and allow it to dissolve
, Advanced pharmacology for NP Exam 2
Study online at https://quizlet.com/_8v3bwd
23. Donald has been diagnosed with hyperlipidemia. Based on his lipid profile,
atorvastatin is prescribed. Rhabdomyolysis is a rare but serious adverse re-
sponse to this drug. Donald should be told to:: Report muscle weakness or tenderness and
dark urine to his provider immediately.
24. Which of the following diagnostic results would NOT indicate a problem
related to a reductase inhibitor?: Increased white blood cell count
25. Because of the pattern of cholesterol synthesis, reductase inhibitors are
given: In the evening in a single daily dose
26. Niaspan, an extended-release form of niacin, was previously prescribed to
treat a patient's hypertriglycerides. However, the FDA withdrew its approval
of the drug. Which of the following drugs with research efficacy should be
substituted?: 1 or 2:
1. Statins
2. Fibrates
27. Niaspan is less likely to cause which side effect that is common to niacin?: -
Cutaneous flushing
28. Dulcea has type 2 diabetes and a high triglyceride level. She has been
prescribed gemfibrozil to treat her hypertriglyceridemia. A history of which of
the following might contraindicate the use of this drug?: Gallbladder disease
29. Many patients with hyperlipidemia are treated with more than one drug.
Combining a fibric acid derivative such as gemfibrozil with which of the follow-
ing is not recommended? The drug and the reason must both be correct for
the answer to be correct.: Reductase inhibitors, due to an increased risk for rhabdomyolysis
30. Felicity has been prescribed colestipol to treat her hyperlipidemia. Unlike
other antilipidemics, this drug:: Exchanges chloride ions for negatively charged acids in the bowel
31. Because of their site of action, bile acid sequestering resins:: Should be administered
separately from other drugs by at least four hours
32. Colestipol comes in a powdered form. The patient is taught to:: Mix the powder
with four to six ounces of milk or fruit juice
33. The choice of diuretic to use in treating hypertension is based on:: Level of kidney
function with a thiazide diuretic being used for an estimated glomerular filtration rate higher than the mid-40 mL/min
range
Study online at https://quizlet.com/_8v3bwd
1. Ray has been diagnosed with hypertension and it is determined that an
angiotensin-converting enzyme inhibitor is needed. Prior to prescribing this
drug, the nurse practitioner (NP) should assess for:: Decreased renal function
2. Angiotensin-converting enzyme (ACE) inhibitors are the drug of choice in
treating hypertension in diabetic patients because they:: All of the above:
Improve insulin sensitivity
Improve renal hemodynamics
Reduce the production of angiotensin II
3. A potentially life-threatening adverse response to an ACE inhibitor is an-
gioedema. Which of the following statements is true about this adverse re-
sponse?: Swelling of the tongue and hoarseness are the most common symptoms.
4. ACE inhibitors are useful in a variety of disorders. Which of the following
statements is true about both their usefulness in a particular disorder and the
reason for their use?: Both 1 and 2 are true:
1. They are useful to prevent stable angina because they decrease the thickening of vascular walls due to decreased
modified release.
2. They are useful to prevent heart failure because they reduce remodeling of injured myocardial tissues.
5. Despite good blood pressure control, an NP might change a patient's drug
from an ACE inhibitor to an angiotensin II receptor blocker (ARB) because the
ARB:: Does not produce a dry, hacking cough
6. While taking an ARB, patients need to avoid certain over-the-counter drugs
without irst consulting the provider because:: Both 1 and 2:
1. Cimetidine is metabolized by the CYP3A4 isoenzymes
2. Nonsteroidal anti-inflammatory drugs reduce prostaglandin levels
7. Laboratory monitoring for patients on ACE inhibitors or ARBs should include:-
: Serum creatinine levels with the drug dosage reduced for values greater than 2.5 mg/dL
8. Jacob has hypertension, for which a calcium channel blocker has been pre-
scribed. This drug helps control blood pressure because it:: Decreases the amount of
calcium inside the cell
9. Which of the following adverse effects may occur due to a dihydropyri-
dine-type calcium channel blocker?: Edema of the hands and feet
, Advanced pharmacology for NP Exam 2
Study online at https://quizlet.com/_8v3bwd
10. Patient teaching related to amlodipine includes:: Avoid grapefruit juice as it affects the
metabolism of this drug.
11. Vera, age 70, has isolated systolic hypertension. Calcium channel blocker
dosages for her should be:: Started at about half the usual dosage
12. Larry has heart failure, which is being treated with digoxin because it ex-
hibits:: Negative inotropism
13. Furosemide is added to a treatment regimen for heart failure that includes
digoxin. Monitoring for this combination includes:: Serum potassium
14. Which of the following create a higher risk for digoxin toxicity? Both the
cause and the reason for it must be correct.: Administration to older adults because of reduced
renal function
15. Serum digoxin levels are monitored for potential toxicity. Monitoring should
occur:: Because a reference point is needed to adjust dosage
16. Which of the following is true about procainamide and its dosing schedule?:
17. Rodrigo has been prescribed procainamide after a myocardial infarction. He
is monitored for dyspnea, jugular venous distention, and peripheral edema
because they may indicate:: Onset of congestive heart failure
18. Amiodarone has been prescribed in a patient with a supraventricular dys-
rhythmia. Patient teaching should include all of the following EXCEPT:: Take a hot
shower or bath if you feel dizzy.
19. The NP orders a thyroid panel for a patient on amiodarone. The patient
tells the NP that he does not have thyroid disease and wants to know why the
test has been ordered. Which is a correct response?: Amiodarone inhibits an enzyme that is
important in making thyroid hormone and can cause hypothyroidism.
20. Isosorbide dinitrate is prescribed for a patient with chronic stable angina.
This drug is administered twice daily, but the schedule is 7 a.m. and 2 p.m.
because:: Nitrate tolerance can develop.
21. Art is a 55-year-old smoker who has been diagnosed with angina and placed
on nitrates. He complains of headaches after using his nitrate. An appropriate
reply might be::
22. In teaching about the use of sublingual nitroglycerine, the patient should be
instructed:: To place one tablet under the tongue if chest pain occurs and allow it to dissolve
, Advanced pharmacology for NP Exam 2
Study online at https://quizlet.com/_8v3bwd
23. Donald has been diagnosed with hyperlipidemia. Based on his lipid profile,
atorvastatin is prescribed. Rhabdomyolysis is a rare but serious adverse re-
sponse to this drug. Donald should be told to:: Report muscle weakness or tenderness and
dark urine to his provider immediately.
24. Which of the following diagnostic results would NOT indicate a problem
related to a reductase inhibitor?: Increased white blood cell count
25. Because of the pattern of cholesterol synthesis, reductase inhibitors are
given: In the evening in a single daily dose
26. Niaspan, an extended-release form of niacin, was previously prescribed to
treat a patient's hypertriglycerides. However, the FDA withdrew its approval
of the drug. Which of the following drugs with research efficacy should be
substituted?: 1 or 2:
1. Statins
2. Fibrates
27. Niaspan is less likely to cause which side effect that is common to niacin?: -
Cutaneous flushing
28. Dulcea has type 2 diabetes and a high triglyceride level. She has been
prescribed gemfibrozil to treat her hypertriglyceridemia. A history of which of
the following might contraindicate the use of this drug?: Gallbladder disease
29. Many patients with hyperlipidemia are treated with more than one drug.
Combining a fibric acid derivative such as gemfibrozil with which of the follow-
ing is not recommended? The drug and the reason must both be correct for
the answer to be correct.: Reductase inhibitors, due to an increased risk for rhabdomyolysis
30. Felicity has been prescribed colestipol to treat her hyperlipidemia. Unlike
other antilipidemics, this drug:: Exchanges chloride ions for negatively charged acids in the bowel
31. Because of their site of action, bile acid sequestering resins:: Should be administered
separately from other drugs by at least four hours
32. Colestipol comes in a powdered form. The patient is taught to:: Mix the powder
with four to six ounces of milk or fruit juice
33. The choice of diuretic to use in treating hypertension is based on:: Level of kidney
function with a thiazide diuretic being used for an estimated glomerular filtration rate higher than the mid-40 mL/min
range
