CSMLS CHEMISTRY + HEMATOLOGY
QUESTIONS WITH CORRECT
ANSWERS
Which of the following ionization techniques is preferred for trace elements?
a. matrix assisted laser desorption
b. inductively coupled plasma
c. electrospray
d. chemical - Correct Answers -b. inductively coupled plasma (mass spec)
*trace element & heavy metal analysis
Which of the following factors may cause an albumin result to fail a delta check flag
when using the bromocresol green method?
a. patient was recumbent during venipuncture
b. specimen was collected in Li heparin
c. specimen was icteric
d. patient was not fasting - Correct Answers -a. patient recumbent during venipuncture
(same as having tourniquet on too long >1 min cause hemoconcentration)
Which of the following requirements must be induced in the setup of a lab info system?
a. specimen assigned a unique barcode label
b. instrumentation interfaced with the lis
c. lis interfaced to electronic medical record
d. identification code and password to each user - Correct Answers -d. identification
code and password to each user
(security & privacy always primary requirement)
Which of the following components is responsible for autoverification?
a. server
b. output device
c. analyzer
d. middleware - Correct Answers -d. middleware
Which of the following factors is most likely to cause a falsely increased creatinine
clearance result in a 24 hr urine specimen?
a. including first morning voided urine in sample collection
b. using mid-stream voided urine fo the sample collection
c. failing to include the last voided urine at the end of the sample collection
d. failing to include some of the urine during sample collection - Correct Answers -a.
,What is the effect on sodium quality control results if the calibration standards are over-
diluted?
a. decreased imprecision
b. positive shift
c. negative shift
d. increased imprecision - Correct Answers -b
(over diluting cal = read lower = less steep curve)
What is the molal freezing point of a sample with an osmolality of 403 mOsm/Kg?
a. -0.075C
b. -0.75C
c. 0.075C
d. 0.75C - Correct Answers -b. -0.75C
403 X (-1.86C/1Osm) X (1Osm/1000mOsm) = -0.75
Which of the following conditions correlates with a plasma phosphorus of 0.35 mmol/L?
a. rhabdomyolysis
b. acromegaly
c. hypoparathyroidism
d. DKA - Correct Answers -d. DKA
Which of the following ionization methods may be used for liquid chromatography mass
spectrometry?
a. inductively coupled plasma
b. electrospray
c. electron
d. MALDI - Correct Answers -b. electrospray
Given a serum chloride of 30 mmol/L what is the expected chloride level in the CSF?
a. 30 mmol/L
b. 20 mmol/L
c. 50 mmol/L
d. 10 mmol/L - Correct Answers -c. 50 mmol/L
**CSF chloride is 20 mmol/L higher than serum chloride levels
(Sodium is the same in serum and CSF)
Factors that contribute to a PCO2 electrode requiring 60-120 sec. to reach equilibrium
include:
a. diffusion characteristics of the membrane
b. actual blood PO2
c. type of calibrating standard
d. potential of the polarizing mercury cell - Correct Answers -a
An emphysema patient suffering from fluid accumulation in the alveolar spaces is likely
to be in what metabolic state?
, a. respiratory acidosis
b. respiratory alkalosis
c. metabolic acidosis
d. metabolic alkalosis - Correct Answers -a
At blood pH of 7.40 what is the ratio of bicarbonate to carbonic acid?
a. 15:1
b. 20:1
c. 25:1
d. 30:1 - Correct Answers -b
The reference rang for the pH of arterial blood measured at 37C is:
a. 7.28-7.34
b. 7.33-7.37
c. 7.35-7.45
d. 7.45-7.50 - Correct Answers -c
A common cause of respiratory alkalosis is?
a. vomiting
b. starvation
c. asthma
d. hyperventilation - Correct Answers -d
Acidosis and alkalosis are best defined as fluctuations in pH and CO2 content changes
due to changes in:
a. Bohr effect
b. O2 content
c. bicarbonate buffer
d. carbonic anhydrase - Correct Answers -c
A blood gas sample was sent to the lab on ice and a bubble was present in the syringe.
The blood had been exposed to room air for at least 30 minutes. The following changes
in blood gases will occur:
a. CO2 increased, PCO2 decreased
b. Co2 content & PO2 increased; pH increased
c. CO2 content and PCo2 decreased; pH decreased
d. PO2 increased, HCO3 decreased - Correct Answers -d
Select the test which evaluates renal tubular function:
a. IVP
b. creatinine clearance
c. osmolarity
d. microscopic urinalysis - Correct Answers -c
The degree to which the kidney concentrates the glomerular filtrate can be determined
by:
QUESTIONS WITH CORRECT
ANSWERS
Which of the following ionization techniques is preferred for trace elements?
a. matrix assisted laser desorption
b. inductively coupled plasma
c. electrospray
d. chemical - Correct Answers -b. inductively coupled plasma (mass spec)
*trace element & heavy metal analysis
Which of the following factors may cause an albumin result to fail a delta check flag
when using the bromocresol green method?
a. patient was recumbent during venipuncture
b. specimen was collected in Li heparin
c. specimen was icteric
d. patient was not fasting - Correct Answers -a. patient recumbent during venipuncture
(same as having tourniquet on too long >1 min cause hemoconcentration)
Which of the following requirements must be induced in the setup of a lab info system?
a. specimen assigned a unique barcode label
b. instrumentation interfaced with the lis
c. lis interfaced to electronic medical record
d. identification code and password to each user - Correct Answers -d. identification
code and password to each user
(security & privacy always primary requirement)
Which of the following components is responsible for autoverification?
a. server
b. output device
c. analyzer
d. middleware - Correct Answers -d. middleware
Which of the following factors is most likely to cause a falsely increased creatinine
clearance result in a 24 hr urine specimen?
a. including first morning voided urine in sample collection
b. using mid-stream voided urine fo the sample collection
c. failing to include the last voided urine at the end of the sample collection
d. failing to include some of the urine during sample collection - Correct Answers -a.
,What is the effect on sodium quality control results if the calibration standards are over-
diluted?
a. decreased imprecision
b. positive shift
c. negative shift
d. increased imprecision - Correct Answers -b
(over diluting cal = read lower = less steep curve)
What is the molal freezing point of a sample with an osmolality of 403 mOsm/Kg?
a. -0.075C
b. -0.75C
c. 0.075C
d. 0.75C - Correct Answers -b. -0.75C
403 X (-1.86C/1Osm) X (1Osm/1000mOsm) = -0.75
Which of the following conditions correlates with a plasma phosphorus of 0.35 mmol/L?
a. rhabdomyolysis
b. acromegaly
c. hypoparathyroidism
d. DKA - Correct Answers -d. DKA
Which of the following ionization methods may be used for liquid chromatography mass
spectrometry?
a. inductively coupled plasma
b. electrospray
c. electron
d. MALDI - Correct Answers -b. electrospray
Given a serum chloride of 30 mmol/L what is the expected chloride level in the CSF?
a. 30 mmol/L
b. 20 mmol/L
c. 50 mmol/L
d. 10 mmol/L - Correct Answers -c. 50 mmol/L
**CSF chloride is 20 mmol/L higher than serum chloride levels
(Sodium is the same in serum and CSF)
Factors that contribute to a PCO2 electrode requiring 60-120 sec. to reach equilibrium
include:
a. diffusion characteristics of the membrane
b. actual blood PO2
c. type of calibrating standard
d. potential of the polarizing mercury cell - Correct Answers -a
An emphysema patient suffering from fluid accumulation in the alveolar spaces is likely
to be in what metabolic state?
, a. respiratory acidosis
b. respiratory alkalosis
c. metabolic acidosis
d. metabolic alkalosis - Correct Answers -a
At blood pH of 7.40 what is the ratio of bicarbonate to carbonic acid?
a. 15:1
b. 20:1
c. 25:1
d. 30:1 - Correct Answers -b
The reference rang for the pH of arterial blood measured at 37C is:
a. 7.28-7.34
b. 7.33-7.37
c. 7.35-7.45
d. 7.45-7.50 - Correct Answers -c
A common cause of respiratory alkalosis is?
a. vomiting
b. starvation
c. asthma
d. hyperventilation - Correct Answers -d
Acidosis and alkalosis are best defined as fluctuations in pH and CO2 content changes
due to changes in:
a. Bohr effect
b. O2 content
c. bicarbonate buffer
d. carbonic anhydrase - Correct Answers -c
A blood gas sample was sent to the lab on ice and a bubble was present in the syringe.
The blood had been exposed to room air for at least 30 minutes. The following changes
in blood gases will occur:
a. CO2 increased, PCO2 decreased
b. Co2 content & PO2 increased; pH increased
c. CO2 content and PCo2 decreased; pH decreased
d. PO2 increased, HCO3 decreased - Correct Answers -d
Select the test which evaluates renal tubular function:
a. IVP
b. creatinine clearance
c. osmolarity
d. microscopic urinalysis - Correct Answers -c
The degree to which the kidney concentrates the glomerular filtrate can be determined
by:
