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Trauma Certified Registered Nurse (TCRN) – Sepsis – Study Notes and Exam Preparation Material

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This document covers sepsis in trauma patients, including pathophysiology, early recognition, hemodynamic monitoring, infection control, and evidence-based interventions. It is designed to support TCRN exam preparation with high-yield content for critical care and emergency trauma nursing.

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Sepsis


SIRS - Correct answer- >38 or <36
HR >90
RR >20 or pCO2 <32
WBC <4000 or >12000 (or >10% bands)


Sepsis = 2 criteria + source


Severe Sepsis - Correct answer- Sepsis + Hypotension or organ
dysfunction


AMS, renal insufficiency, abnormal coags, abnormal glucose,
lactate >2


Surviving Sepsis - Correct answer- At 3 hours:
-Lactate level
-blood cultures
-IVF 30 mL/kg
-Abx



1

, 2


Unknown Infection - Correct answer- Levaquin 750 mg +
Vancomycin 1 g + Gentamicin 7 mg/kg
-Imipenem is alternative


ENT/Dental Infection - Correct answer- PCN G 4 million units
+ Clindamycin 900 mg + Flagyl 1 g


Meningitis - Correct answer- Ceftriaxone 2 g + Vancomycin 1 g
+ Dex 10 mg
-1 month: Ampicillin 50-75 mg/kg + Cefotaxime 50-75 mg/kg
->1 month: Ceftriaxone 100 mg/kg + Ampicillin
-avoid Ceftriaxone in <30 days due to bilirubin


Pulmonary Infection - Correct answer- Levaquin 750 mg +
Vanc +/- Gentamicin
-Alternate is Ceftriaxone 1-2 g + Azithromycin 500 mg


GI/UG Infection - Correct answer- Zosyn 3.375 g or Unasyn 3 g
+/- Gent


Skin Infection - Correct answer- Zosyn 3.375 g + Vanc 1 g +
Gent 7 mg/kg




2

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