Midterm Exam – Chamberlain
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1. After entry into the study, patients were first classified into three groups, those
who had a previous AMI, those with a first AMI who were at high risk for other
cardiovascular diseases such as congestive heart failure, and those with a first
AMI who were at low risk for other cardiovascular diseases. Which
term best describes the study design?
Answer> Randomized clinical trial with stratified
randomization
2. After assignment to treatment group, 77% of those in the placebo group
were men, while 80% of those in the drug X group were men. Which statement is
most likely to be true?
Answer> Randomization was successful since the investigators did not alter the
selection of participants in either group in order to ensure equal percentages of
men
3. A preliminary analysis was conducted after 6 months and found that 87% of
participants in the placebo group and 85% of those in the drug X group had
taken more than 90% of their prescribed dosages. Which statement best
describes this finding?
,Answer> The characteristics of patients who failed to comply with the treatment
dosages should be assessed as they may differ from those who complied
4. Which of the following statements best describes the reason for conduct-
ing the study as a double-blind trial?
Answer> Double blinding ensures that potential biases regarding selection,
follow-up, and analysis can be reduced
5. The following data come from a study of approaches to smoking cessation.
Smokers who want to quit were randomized to one of four groups
control ..... brochures and a monthly phone call from a counselor. Participants
received mailed surveys at 8, 16, and 24 months after randomization. The results
after 2 years are in the table below. Which group had the least success in terms
of quitting smoking?
Answer> Group QS
6. The following data come from a study of approaches to smoking cessation.
Smokers who want to quit were randomized to one of four groups
control group C who received no intervention assistance, quitting guide group Q
who received brochures about how to quit smoking, quitting guide and support
group QS who received quitting brochures as well as social support brochures
listing benefits of smoking cessation, and telephone support group T who
received the brochures and a monthly phone call from a counselor. Partici-
pants received mailed surveys at 8, 16, and 24 months after randomization. The
, results after 2 years are in the table below. What is the main purpose of
randomization in this study?
Answer> To avoid assigning more persons who have tried and failed to quit in the
past to the control group
7. The nurse practitioner is reviewing a recent study that utilizes analytic
epidemiology by means of a cohort study design. The cohort study design
informs the practitioner about which of the following
Answer> Outcomes that develop from an exposure
8. A group of providers have implemented population-based intervention and
are now assessing the efficacy of the intervention. Which of the following
would be an example of a population based outcome?
Answer> Decreased mortality rate compared to previous year
9. Appraisal of research publications is critical as providers assess for rele-
vance to population health. Which of the following items should be considered
during the appraisal process? Select all that apply.
Answer> Outcome measure, Trans- parency, Internal Validity
10. What is being compared in a cohort study design?
Answer> The incidence of a disease between exposed and non-exposed individuals
11. Analytic epidemiology is best described as
Answer> Studies that investigate origins and casuals' factors of health-related
events