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A&P HESI A2 Practice Test Questions 2026 | Nursing Exam Prep with Answers

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Boost your confidence and excel in the HESI A2 Anatomy & Physiology section with our latest 2026 practice test questions. This resource includes carefully curated questions with correct answers, designed to mirror the actual exam format. Perfect for nursing school applicants, these practice tests help you review key concepts, identify weak areas, and maximize your scores. Get exam-ready and study smarter with this essential HESI A2 prep tool!

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A&P HESI A2 Practice Test Questions
2026 | Nursing Exam Prep with Answers
1. What type of carbohydrate does amylase specifically target for breakdown?

Starch

Fiber

Protein

Fat

2. Describe the relationship between the skull and the spinal cord using
anatomical terminology.

The skull is positioned to the side of the spinal cord, indicating a
lateral relationship.

The skull is positioned below the spinal cord, indicating an inferior
relationship.

The skull is positioned above the spinal cord, indicating a superior
relationship.

The skull is positioned behind the spinal cord, indicating a posterior
relationship.

3. The function of the enzyme salivary amylase is to:

to moisten food so a bolus can be formed

to emulsify fats

to break down carbohydrates

to break down proteins

,4. If a patient has a deficiency in parathyroid hormone, what physiological
effect might you expect to observe?

Decreased muscle contraction strength

Increased bone density

Decreased blood calcium levels

Increased blood calcium levels

5. Which organ system consists of the heart, blood, and blood vessels?

Lymphatic

Endocrine

Cardiovascular

Digestive

6. What is the shape of the cells in columnar epithelium?

Flat

Cube-shaped

Pillar-shaped

Irregular

7. If a patient presents with symptoms of beriberi, what dietary
recommendations would you provide to ensure adequate thiamine intake?

Increase consumption of whole grains, legumes, and fortified
cereals.

Increase intake of vitamin C-rich fruits and vegetables.

Reduce intake of carbohydrates and increase protein consumption.

, Focus on high-fat foods to compensate for nutrient loss.

8. Which organ system prevents water loss, the entry of bacteria into the body,
and synthesizes vitamin D?

immune system

digestive system

skeletal system

integumentary system

9. The ribs are _________________ to the lungs in the human body

superior

anterior

deep

medial

10. The ________ gland sits along the superior border of the kidney.

Thyroid

Pancreas

Thymus

Adrenal

11. The rhythmic contractions that propel food through the GI tract illustrated in
this diagram are called:

Swallowing

GERD

, Peristalsis

Bolus

12. What type of cell is responsible for myelinating axons in the peripheral
nervous system?

Oligodendrocyte

Astrocyte

Schwann cell

Microglia

13. What is the primary role of the nervous system in relation to the muscular
system?

The muscles of the body produce chemicals that feed the nerves.

The nervous system releases chemicals that remove excess waste
from the muscles.

The nervous system tells the muscles how to respond to the
environment.

The muscular system provides input that allows the nerves to make
decisions.

14. Describe the location of the adrenal glands in relation to the kidneys.

The adrenal glands are located lateral to the kidneys.

The adrenal glands are located inferior to the kidneys.

The adrenal glands are located posterior to the kidneys.

The adrenal glands are located superior to the kidneys.

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