Hematology Exam 3 Complete Exam Study
Guide 2026 | 130+ Questions & Answers with
Detailed Explanations | Guaranteed Pass
Exam Prep
Description
This complete exam study guide contains 130+ carefully structured
questions and answers designed to help students master the most
important exam topics and achieve outstanding results. Each question is
accompanied by a clear and detailed explanation, making it easier to
understand key concepts and strengthen exam preparation.
The guide is organized in a simple and student-friendly format,
allowing learners to review essential material quickly while practicing
realistic exam-style questions. By working through these 130+ Q&A,
students can reinforce their knowledge, identify important topics, and
improve their confidence before taking the exam.
This resource is ideal for final exam revision, self-testing, and
comprehensive exam preparation, making it a valuable tool for
students who want a reliable study guide and a higher chance of
passing their exam successfully.
What RBC inclusion is composed of DNA and seen in post-splenectomy, megaloblastic
anemias, or hemolytic anemias? -answer ✅✅✅✅Howell-Jolly body
What RBC inclusion is composed of RNA and is associated with decreased RBC
survival & erythroid hyperplastic marrow? -answer ✅✅✅✅Reticulocyte/polychromasia
What RBC inclusion is composed of iron and is seen in sideroblastic anemia or
thalassemia? -answer ✅✅✅✅Pappenheimer body
,What RBC inclusion is composed of precipitated hemoglobin and seen in G6PD
deficiency using supravital stain? -answer ✅✅✅✅Heinz body
What RBC inclusion is crystalized hemoglobin C and seen in Hemoglobin C disease? -
answer ✅✅✅✅C crystal
What is a ringed sideroblast composed of? -answer ✅✅✅✅Iron
What RBC inclusion is composed of RNA aggregates and is seen in thalassemia or lead
poisoning? -answer ✅✅✅✅Basophilic stippling
What is a nucleated red blood cell composed of? -answer ✅✅✅✅DNA
What is the formula for calculating hematocrit? -answer ✅✅✅✅RBC x MCV/10
What affects the MCV? -answer ✅✅✅✅Agglutination
Will an increased WBC count affect the RBC count? -answer ✅✅✅✅Yes
Does lipemia affect the hemoglobin or hematocrit? -answer ✅✅✅✅Hemoglobin
What is the formula for calculating the MCV? -answer ✅✅✅✅Hct x 10/RBC
What is the formula for calculating the MCH? -answer ✅✅✅✅Hgb x 10/RBC
What is the formula for calculating the MCHC? -answer ✅✅✅✅Hgb x 100/Hct
What is the reference range for MCV? -answer ✅✅✅✅80-100 fL
What is the reference range for MCH? -answer ✅✅✅✅28-32 pg
What is the reference range for MCHC? -answer ✅✅✅✅32-36% g/dl
What is the reference range for RDW? -answer ✅✅✅✅11.5-14.5%
What is a macrocytic anemia we learned about? -answer ✅✅✅✅Megaloblastic
anemia
What is defective in megaloblastic anemia? -answer ✅✅✅✅Defective DNA synthesis
from B12 or folate; poor diet
What will the bone marrow show in megaloblastic anemia? -answer
✅✅✅✅Asynchrony, karryohexis, giant metamyelocytes, & bands
,What are the laboratory results for megaloblastic anemia? -answer
✅✅✅✅Hypersegmented neutrophils, increased DBili, Bili, and LD, decreased retic,
pancytopenia
How is megaloblastic anemia treated? -answer ✅✅✅✅Vitamin therapy
What tapeworm is associated with megaloblastic anemia? -answer
✅✅✅✅Diphyllobothrium latum
What are causes of folate deficient? -answer ✅✅✅✅Alcoholism, poverty, pregnancy,
What do you lack in pernicious anemia? -answer ✅✅✅✅Intrinsic factor
What is the function of intrinsic factor? -answer ✅✅✅✅Aids in B12 absorption
What test confirms pernicious anemia? -answer ✅✅✅✅Schilling test
What are macrocytic cells associated with other than megaloblastic anemia? -answer
✅✅✅✅Liver disease, alcoholism, reticulocytosis,
What are causes of iron deficiency anemia? -answer ✅✅✅✅Chronic blood loss, poor
diet, malabsorption,
What are the laboratory results for iron deficiency anemia? -answer ✅✅✅✅Decreased
Fe, Ferritin, increased TIBC, increased retic only after therapy
What are the laboratory findings for anemia of chronic disease? -answer
✅✅✅✅Decreased iron, TIBC, increased ferritin
What is the sequence of development in IDA? -answer ✅✅✅✅1. Stores depleted
2. Iron deficient erythropoiesis
3. Hgb/hct depletion
4. Symptoms appear
What is the treatment for IDA? -answer ✅✅✅✅Treat underlying cause, iron
supplements (based on severity: oral, transfusion, injection)
What is hemosiderosis? -answer ✅✅✅✅Increased iron in reticuloendothelial cells
What is hemochromatosis? -answer ✅✅✅✅More severe than hemosiderosis, excess
iron is stored in the liver
, What is the treatment for hemochromatosis? -answer ✅✅✅✅Phlebotomy or chelation
therapy to deplete iron stores
What are some microcytic anemias? -answer ✅✅✅✅Iron deficiency anemia,
hemochromatosis, hemosiderosis thalassemia, anemia of chronic disease, lead
poisoning, sideroblastic anemia
What RBC inclusion is seen in lead poisoning? -answer ✅✅✅✅Coarse basophilic
stippling
What happens in lead poisoning? -answer ✅✅✅✅Lead blocks heme production at
several spots resulting in low heme production and low hemoglobin
What is defective in sideroblastic anemia? -answer ✅✅✅✅Abnormal heme
metabolism is present
What is defective in beta thalassemia? -answer ✅✅✅✅Beta chains are reduced or
absent, alpha chains are increased
What is the most common descent for beta thalassemia? -answer
✅✅✅✅Mediterranean, South East Asians, and African American
What are the laboratory results for beta thalassemia? -answer ✅✅✅✅Target cells,
basophilic stippling, increased A2 & F in hemoglobin electrophoresis
What is a 4 gene deletion called in alpha thalassemia? -answer ✅✅✅✅Hydrops fetalis
(alpha thalassemia major)
What is a 3 gene deletion in alpha thalassemia? -answer ✅✅✅✅Hgb H (4 beta
chains)
What is a 2 gene deletion in alpha thalassemia? -answer ✅✅✅✅Alpha thalassemia
minor
What is a single gene deletion in alpha thalassemia? -answer ✅✅✅✅Silent carrier
What hemoglobins are decreased in alpha thalassemia? -answer ✅✅✅✅Hgb A, A2, &
F
What is it called to have 4 gamma chains present? -answer ✅✅✅✅Hgb Barts
What are the laboratory results for alpha thalassemia? -answer ✅✅✅✅Target cells,
basophilic stippling
Guide 2026 | 130+ Questions & Answers with
Detailed Explanations | Guaranteed Pass
Exam Prep
Description
This complete exam study guide contains 130+ carefully structured
questions and answers designed to help students master the most
important exam topics and achieve outstanding results. Each question is
accompanied by a clear and detailed explanation, making it easier to
understand key concepts and strengthen exam preparation.
The guide is organized in a simple and student-friendly format,
allowing learners to review essential material quickly while practicing
realistic exam-style questions. By working through these 130+ Q&A,
students can reinforce their knowledge, identify important topics, and
improve their confidence before taking the exam.
This resource is ideal for final exam revision, self-testing, and
comprehensive exam preparation, making it a valuable tool for
students who want a reliable study guide and a higher chance of
passing their exam successfully.
What RBC inclusion is composed of DNA and seen in post-splenectomy, megaloblastic
anemias, or hemolytic anemias? -answer ✅✅✅✅Howell-Jolly body
What RBC inclusion is composed of RNA and is associated with decreased RBC
survival & erythroid hyperplastic marrow? -answer ✅✅✅✅Reticulocyte/polychromasia
What RBC inclusion is composed of iron and is seen in sideroblastic anemia or
thalassemia? -answer ✅✅✅✅Pappenheimer body
,What RBC inclusion is composed of precipitated hemoglobin and seen in G6PD
deficiency using supravital stain? -answer ✅✅✅✅Heinz body
What RBC inclusion is crystalized hemoglobin C and seen in Hemoglobin C disease? -
answer ✅✅✅✅C crystal
What is a ringed sideroblast composed of? -answer ✅✅✅✅Iron
What RBC inclusion is composed of RNA aggregates and is seen in thalassemia or lead
poisoning? -answer ✅✅✅✅Basophilic stippling
What is a nucleated red blood cell composed of? -answer ✅✅✅✅DNA
What is the formula for calculating hematocrit? -answer ✅✅✅✅RBC x MCV/10
What affects the MCV? -answer ✅✅✅✅Agglutination
Will an increased WBC count affect the RBC count? -answer ✅✅✅✅Yes
Does lipemia affect the hemoglobin or hematocrit? -answer ✅✅✅✅Hemoglobin
What is the formula for calculating the MCV? -answer ✅✅✅✅Hct x 10/RBC
What is the formula for calculating the MCH? -answer ✅✅✅✅Hgb x 10/RBC
What is the formula for calculating the MCHC? -answer ✅✅✅✅Hgb x 100/Hct
What is the reference range for MCV? -answer ✅✅✅✅80-100 fL
What is the reference range for MCH? -answer ✅✅✅✅28-32 pg
What is the reference range for MCHC? -answer ✅✅✅✅32-36% g/dl
What is the reference range for RDW? -answer ✅✅✅✅11.5-14.5%
What is a macrocytic anemia we learned about? -answer ✅✅✅✅Megaloblastic
anemia
What is defective in megaloblastic anemia? -answer ✅✅✅✅Defective DNA synthesis
from B12 or folate; poor diet
What will the bone marrow show in megaloblastic anemia? -answer
✅✅✅✅Asynchrony, karryohexis, giant metamyelocytes, & bands
,What are the laboratory results for megaloblastic anemia? -answer
✅✅✅✅Hypersegmented neutrophils, increased DBili, Bili, and LD, decreased retic,
pancytopenia
How is megaloblastic anemia treated? -answer ✅✅✅✅Vitamin therapy
What tapeworm is associated with megaloblastic anemia? -answer
✅✅✅✅Diphyllobothrium latum
What are causes of folate deficient? -answer ✅✅✅✅Alcoholism, poverty, pregnancy,
What do you lack in pernicious anemia? -answer ✅✅✅✅Intrinsic factor
What is the function of intrinsic factor? -answer ✅✅✅✅Aids in B12 absorption
What test confirms pernicious anemia? -answer ✅✅✅✅Schilling test
What are macrocytic cells associated with other than megaloblastic anemia? -answer
✅✅✅✅Liver disease, alcoholism, reticulocytosis,
What are causes of iron deficiency anemia? -answer ✅✅✅✅Chronic blood loss, poor
diet, malabsorption,
What are the laboratory results for iron deficiency anemia? -answer ✅✅✅✅Decreased
Fe, Ferritin, increased TIBC, increased retic only after therapy
What are the laboratory findings for anemia of chronic disease? -answer
✅✅✅✅Decreased iron, TIBC, increased ferritin
What is the sequence of development in IDA? -answer ✅✅✅✅1. Stores depleted
2. Iron deficient erythropoiesis
3. Hgb/hct depletion
4. Symptoms appear
What is the treatment for IDA? -answer ✅✅✅✅Treat underlying cause, iron
supplements (based on severity: oral, transfusion, injection)
What is hemosiderosis? -answer ✅✅✅✅Increased iron in reticuloendothelial cells
What is hemochromatosis? -answer ✅✅✅✅More severe than hemosiderosis, excess
iron is stored in the liver
, What is the treatment for hemochromatosis? -answer ✅✅✅✅Phlebotomy or chelation
therapy to deplete iron stores
What are some microcytic anemias? -answer ✅✅✅✅Iron deficiency anemia,
hemochromatosis, hemosiderosis thalassemia, anemia of chronic disease, lead
poisoning, sideroblastic anemia
What RBC inclusion is seen in lead poisoning? -answer ✅✅✅✅Coarse basophilic
stippling
What happens in lead poisoning? -answer ✅✅✅✅Lead blocks heme production at
several spots resulting in low heme production and low hemoglobin
What is defective in sideroblastic anemia? -answer ✅✅✅✅Abnormal heme
metabolism is present
What is defective in beta thalassemia? -answer ✅✅✅✅Beta chains are reduced or
absent, alpha chains are increased
What is the most common descent for beta thalassemia? -answer
✅✅✅✅Mediterranean, South East Asians, and African American
What are the laboratory results for beta thalassemia? -answer ✅✅✅✅Target cells,
basophilic stippling, increased A2 & F in hemoglobin electrophoresis
What is a 4 gene deletion called in alpha thalassemia? -answer ✅✅✅✅Hydrops fetalis
(alpha thalassemia major)
What is a 3 gene deletion in alpha thalassemia? -answer ✅✅✅✅Hgb H (4 beta
chains)
What is a 2 gene deletion in alpha thalassemia? -answer ✅✅✅✅Alpha thalassemia
minor
What is a single gene deletion in alpha thalassemia? -answer ✅✅✅✅Silent carrier
What hemoglobins are decreased in alpha thalassemia? -answer ✅✅✅✅Hgb A, A2, &
F
What is it called to have 4 gamma chains present? -answer ✅✅✅✅Hgb Barts
What are the laboratory results for alpha thalassemia? -answer ✅✅✅✅Target cells,
basophilic stippling
