1007048221-AQA-Biology-Infection-and-Response-GraspIT-GCSE-Re-usable-Worksheet
1007048221-AQA-Biology-Infection-and-Response-GraspIT-GCSE-Re-usable-Worksheet.pdf
: Questions and Answers 3/7/2026
GraspIT – AQA GCSE Infection and Response
A. Infection and Response part 1 – Communicable diseases (viral, bacterial,
fungal and protist)
1. Tuberculosis (TB) is a communicable disease caused by a bacterium. TB is spread by droplets in
the air when an infected person sneezes or coughs.
a) Suggest which organ will be infected first when a person contracts TB. (1)
b) Explain why people who live in densely populated areas are more likely to be infected with
tuberculosis than people who live in less densely populated areas. (3)
c) Give reasons why a person infected by a very small number of TB bacteria may not actually
develop the disease. (2)
2. Polio is a communicable disease caused by a virus. It can cause irreversible paralysis which often
leads to death. The following data shows the number of cases reported and deaths in the UK.
Year Total cases of Polio reported Total deaths due to Polio
1959 1028 87
1960 378 46
1965 91 19
1968 24 15
1975 3 18
1985 4 29
1990 1 1
1996 1 1
a) Use graph paper and a suitable method to display the data relating to deaths from polio using
the table. (4)
(Remember to add labels)
b) Calculate the percentage decrease in deaths from 1959 to 1975. (2)
Give your answer to 2 significant figures and show your working.
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1007048221-AQA-Biology-Infection-and-Response-GraspIT-GCSE-Re-usable-Worksheet.pdf
1007048221-AQA-Biology-Infection-and-Response-GraspIT-GCSE-Re-usable-Worksheet.pdf 3/7/2026, 7:45:28 PM
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1007048221-AQA-Biology-Infection-and-Response-GraspIT-GCSE-Re-usable-Worksheet.pdf
: Questions and Answers 3/7/2026
GraspIT – AQA GCSE Infection and Response
c) Suggest an explanation for the fall in the number of cases between 1959 and 1960 (1)
d) Suggest why there are more deaths than reported cases in some years. (1)
3. Measles is a highly infectious viral disease which can be fatal. Children are normally vaccinated
at 1 year of age and then again at 3 years 4 months of age.
a) Explain how the disease spreads from one person to another (2)
b) Suggest 2 explanations why children need a follow up vaccination at 3 years 4 months of age. (2)
4. Explain why plants with Tobacco Mosaic Virus (TMV) usually have stunted growth. (2)
5. Smoking can cause diseases such as cancer. Explain why this is not a communicable disease. (2)
6. Extended response question:
A group of Year 12 students are going from a school in the UK to Central Africa. They have
purchased insecticide treated malaria nets. Explain why these nets are more effective than non-
insecticide nets.
Suggest what other control measures should be put in place and why they reduce the chance of
becoming seriously ill with malaria. (6)
© Copyright The PiXL Club Ltd, 2017 2
1007048221-AQA-Biology-Infection-and-Response-GraspIT-GCSE-Re-usable-Worksheet.pdf
1007048221-AQA-Biology-Infection-and-Response-GraspIT-GCSE-Re-usable-Worksheet.pdf 3/7/2026, 7:45:28 PM
1007048221-AQA-Biology-Infection-and-Response-GraspIT-GCSE-Re-usable-Worksheet.pdf
: Questions and Answers 3/7/2026
GraspIT – AQA GCSE Infection and Response
A. Infection and Response part 1 – Communicable diseases (viral, bacterial,
fungal and protist)
1. Tuberculosis (TB) is a communicable disease caused by a bacterium. TB is spread by droplets in
the air when an infected person sneezes or coughs.
a) Suggest which organ will be infected first when a person contracts TB. (1)
b) Explain why people who live in densely populated areas are more likely to be infected with
tuberculosis than people who live in less densely populated areas. (3)
c) Give reasons why a person infected by a very small number of TB bacteria may not actually
develop the disease. (2)
2. Polio is a communicable disease caused by a virus. It can cause irreversible paralysis which often
leads to death. The following data shows the number of cases reported and deaths in the UK.
Year Total cases of Polio reported Total deaths due to Polio
1959 1028 87
1960 378 46
1965 91 19
1968 24 15
1975 3 18
1985 4 29
1990 1 1
1996 1 1
a) Use graph paper and a suitable method to display the data relating to deaths from polio using
the table. (4)
(Remember to add labels)
b) Calculate the percentage decrease in deaths from 1959 to 1975. (2)
Give your answer to 2 significant figures and show your working.
© Copyright The PiXL Club Ltd, 2017 1
1007048221-AQA-Biology-Infection-and-Response-GraspIT-GCSE-Re-usable-Worksheet.pdf
1007048221-AQA-Biology-Infection-and-Response-GraspIT-GCSE-Re-usable-Worksheet.pdf 3/7/2026, 7:45:28 PM
, 1007048221-AQA-Biology-Infection-and-Response-GraspIT-GCSE-Re-usable-Worksheet
1007048221-AQA-Biology-Infection-and-Response-GraspIT-GCSE-Re-usable-Worksheet.pdf
: Questions and Answers 3/7/2026
GraspIT – AQA GCSE Infection and Response
c) Suggest an explanation for the fall in the number of cases between 1959 and 1960 (1)
d) Suggest why there are more deaths than reported cases in some years. (1)
3. Measles is a highly infectious viral disease which can be fatal. Children are normally vaccinated
at 1 year of age and then again at 3 years 4 months of age.
a) Explain how the disease spreads from one person to another (2)
b) Suggest 2 explanations why children need a follow up vaccination at 3 years 4 months of age. (2)
4. Explain why plants with Tobacco Mosaic Virus (TMV) usually have stunted growth. (2)
5. Smoking can cause diseases such as cancer. Explain why this is not a communicable disease. (2)
6. Extended response question:
A group of Year 12 students are going from a school in the UK to Central Africa. They have
purchased insecticide treated malaria nets. Explain why these nets are more effective than non-
insecticide nets.
Suggest what other control measures should be put in place and why they reduce the chance of
becoming seriously ill with malaria. (6)
© Copyright The PiXL Club Ltd, 2017 2
1007048221-AQA-Biology-Infection-and-Response-GraspIT-GCSE-Re-usable-Worksheet.pdf
1007048221-AQA-Biology-Infection-and-Response-GraspIT-GCSE-Re-usable-Worksheet.pdf 3/7/2026, 7:45:28 PM
