Advanced Pharmacology CNS and PNS (all is
not here, you need to study power points!)
questions and answers Graded A+
Central Nervous System?
- receives, integrates, and interprets nerve impulses
- Consists of BRAIN & SPINAL CORD
What are the 3 classes of Stimulants?
Amphetamines - used in kids with ADHD.
Analeptics - used with narcolepsy & as an adjuvant for obstructive sleep apnea.
Anorexiants - suppresses appetite.
General uses for CNS stimulants?
- ADHD
- drug induced respiratory depression
- post anesthesia respiratory depression
- narcolepsy
- obstructive sleep apnea
- exogenous obesity
- sleep wake disturbances
- alzheimer's disease
Action of Amphetamines?
- Sympathomimetic (i.e., adrenergic) stimulate release of norepinephrine in the
sympathetic nerve pathway
- Stimulate the CNS to speed up increases BP, PR, RR
- wakefulness
Amphetamine uses?
o Attention-deficit hyperactivity disorder (ADHD)
o Narcolepsy
, Examples of Amphetamines?
• amphetamine/dextroamphetamine (Adderall XR)
• lisdexamfetamine (Vyvanse)
• methylphenidate (Ritalin, Daytrana (transdermal patch)
• methamphetamine (Desoxyn
Before starting ________ for any reason get baseline weight, BP, pulse, RR.
amphetamines
Action of Analeptics?
• Mild to potent analeptic CNS stimulant
• Stimulates the CNS at all levels—cortex, medulla, and spinal cord
• Increases the depth of respirations by simulating chemoreceptors in the carotid
arteries and aorta
Uses for Analeptics?
• Sleep-wake disturbances
• Narcolepsy
• Dietary supplement/dietary preference
• Diuretic effects (used in some weight-loss supplements)
What are Analeptic drugs?
• Armodafinil (Nuvigil)
• modafinil (Provigil)
• caffeine (Cafcit, 5-hour Energy, Vivarin)
• Doxapram (Dopram)
- Respiratory depression: post-anesthesia or drug induced
Actions of Anorexiants?
• Similar to amphetamines
• Suppress appetite by action on the appetite center in the hypothalamus
What are these drugs?
• phentermine (Adipex-P)
• lorcaserin (Belviq)
not here, you need to study power points!)
questions and answers Graded A+
Central Nervous System?
- receives, integrates, and interprets nerve impulses
- Consists of BRAIN & SPINAL CORD
What are the 3 classes of Stimulants?
Amphetamines - used in kids with ADHD.
Analeptics - used with narcolepsy & as an adjuvant for obstructive sleep apnea.
Anorexiants - suppresses appetite.
General uses for CNS stimulants?
- ADHD
- drug induced respiratory depression
- post anesthesia respiratory depression
- narcolepsy
- obstructive sleep apnea
- exogenous obesity
- sleep wake disturbances
- alzheimer's disease
Action of Amphetamines?
- Sympathomimetic (i.e., adrenergic) stimulate release of norepinephrine in the
sympathetic nerve pathway
- Stimulate the CNS to speed up increases BP, PR, RR
- wakefulness
Amphetamine uses?
o Attention-deficit hyperactivity disorder (ADHD)
o Narcolepsy
, Examples of Amphetamines?
• amphetamine/dextroamphetamine (Adderall XR)
• lisdexamfetamine (Vyvanse)
• methylphenidate (Ritalin, Daytrana (transdermal patch)
• methamphetamine (Desoxyn
Before starting ________ for any reason get baseline weight, BP, pulse, RR.
amphetamines
Action of Analeptics?
• Mild to potent analeptic CNS stimulant
• Stimulates the CNS at all levels—cortex, medulla, and spinal cord
• Increases the depth of respirations by simulating chemoreceptors in the carotid
arteries and aorta
Uses for Analeptics?
• Sleep-wake disturbances
• Narcolepsy
• Dietary supplement/dietary preference
• Diuretic effects (used in some weight-loss supplements)
What are Analeptic drugs?
• Armodafinil (Nuvigil)
• modafinil (Provigil)
• caffeine (Cafcit, 5-hour Energy, Vivarin)
• Doxapram (Dopram)
- Respiratory depression: post-anesthesia or drug induced
Actions of Anorexiants?
• Similar to amphetamines
• Suppress appetite by action on the appetite center in the hypothalamus
What are these drugs?
• phentermine (Adipex-P)
• lorcaserin (Belviq)
