Cytochrome P450
Give this one a try later!
The general name for a large class of enzymes that play a significant role in
drug metabolism and drug interactions.
Found in the liver
drug/drug interactions with P450 enzymes (for SSRIs)
Give this one a try later!
Fluoxetine (Prozac), Paraoxetine (Paxil), Fluvoxamine (Luvox)- raise plasma
concentration levels of TCAs and cause toxicity
,Alparazolam (Xanax)
Give this one a try later!
Benzo
Celexa (citalopram)
Give this one a try later!
SSRI
use: generalized anxiety and MDD
-least D2D reactions
Buspirone (Buspar) (other)
Give this one a try later!
5HT1A- serotonin partial agonist reuptake inhibitor
-anxiolytic drug
-similar to benzo, but not addictive
-dose BID/TID
-lack of interaction with alcohol
-slow onset (1-2 weeks)
Bupropion (Wellbutrin)
Give this one a try later!
, *NDRI
-safe for pregnancy, ↓likely to cause mania, safer choice for bipolar with
depression
nucleus accumbens
Give this one a try later!
structure located in the brainstem and part of the dopaminergic reward
pathway; releases dopamine in response to many drugs contributing to
addictive behavior
PTSD- drugs
Give this one a try later!
-SSRIs- Zoloft and Paxil
-Buspirone (BuSpar) is serotonergic and may be of use
-use benzos with caution
-nightmares-Prazosin (alpha agonist)
-atypical antipsychotics may be useful
-antileptic meds (gabapentin and lamotrigin) may be beneficial
Benzo use
Give this one a try later!
, anxiety, panic disorders, alcohol withdrawal, seizures, insomnia, muscle
spasms, pre-anesthesia sedation, IBS, Restless leg syndrome, and
chemotherapy induced N+V
Benzos: withdrawal SE
Give this one a try later!
anxiety, irritability, insomnia, unpleasant taste of ETOH, decreased
concentration, tremor, delirium, seizure
Hypothalymus
Give this one a try later!
communication between the nervous system and endocrine system,
releases hormones from pituitary gland
controls basic fxn: eating, drinking, sleeping, temperature regulation
Clonidine (other)
Give this one a try later!
Antihypertensive- Alpha2 antagonist
-Off label use for anxiety disorders
Give this one a try later!
The general name for a large class of enzymes that play a significant role in
drug metabolism and drug interactions.
Found in the liver
drug/drug interactions with P450 enzymes (for SSRIs)
Give this one a try later!
Fluoxetine (Prozac), Paraoxetine (Paxil), Fluvoxamine (Luvox)- raise plasma
concentration levels of TCAs and cause toxicity
,Alparazolam (Xanax)
Give this one a try later!
Benzo
Celexa (citalopram)
Give this one a try later!
SSRI
use: generalized anxiety and MDD
-least D2D reactions
Buspirone (Buspar) (other)
Give this one a try later!
5HT1A- serotonin partial agonist reuptake inhibitor
-anxiolytic drug
-similar to benzo, but not addictive
-dose BID/TID
-lack of interaction with alcohol
-slow onset (1-2 weeks)
Bupropion (Wellbutrin)
Give this one a try later!
, *NDRI
-safe for pregnancy, ↓likely to cause mania, safer choice for bipolar with
depression
nucleus accumbens
Give this one a try later!
structure located in the brainstem and part of the dopaminergic reward
pathway; releases dopamine in response to many drugs contributing to
addictive behavior
PTSD- drugs
Give this one a try later!
-SSRIs- Zoloft and Paxil
-Buspirone (BuSpar) is serotonergic and may be of use
-use benzos with caution
-nightmares-Prazosin (alpha agonist)
-atypical antipsychotics may be useful
-antileptic meds (gabapentin and lamotrigin) may be beneficial
Benzo use
Give this one a try later!
, anxiety, panic disorders, alcohol withdrawal, seizures, insomnia, muscle
spasms, pre-anesthesia sedation, IBS, Restless leg syndrome, and
chemotherapy induced N+V
Benzos: withdrawal SE
Give this one a try later!
anxiety, irritability, insomnia, unpleasant taste of ETOH, decreased
concentration, tremor, delirium, seizure
Hypothalymus
Give this one a try later!
communication between the nervous system and endocrine system,
releases hormones from pituitary gland
controls basic fxn: eating, drinking, sleeping, temperature regulation
Clonidine (other)
Give this one a try later!
Antihypertensive- Alpha2 antagonist
-Off label use for anxiety disorders
