SSENTIALSlFORlMEDICATIONlSAFETY,l3RDlEDITION
MULTIPLElCHOICElBASI
,ClCONCEPTS
1. Whichlhealthlcarelprofessionallhaslthelmajorlresponsibilitylforldispensinglprescribedl
medicalldrugslunderltheldirectionloflalpharmacist?
a. Physician
b Nursinglattendantllpr
. actitioner
c. Licensedlnursinglatte
ndantl
d Pharmacyltechnician
.
ACCURATElRESPONSE:-D
Reviewlfeedback:-
>>>Thelphysicianlandlnursinglattendantlhavelthelmajorlresponsibilitylforlprescribinglmedicalldr
ugs,lnotldispensinglthem.lThellicensedlnursinglattendantlhaslthelprimarylresponsibilitylforladmin
isteringlmedicalldrugs,lalthoughlunderlsomelcircumstanceslallicensedlnursinglattendantlmayldispe
nselprescribedlmedicalldrugslbutlthislislnotlhislorlherlmajorlresponsibilitylinlmedicalldrugltherapy
.lThelpharmacyltechnicianlhaslthelmajorlresponsibilitylofldispensinglprescribedlmedicalldrugslun
derltheldirectionloflallicensedlpharmacist.
DIFFICULT:lCognitivelLevel:lRemembering REF: p.l3
2. Whichltermldescribesltheleffectloflalmedicalldruglthatlimproveslbodylfunction?
a. Sideleffect
b Intendedlaction
.
c. Adverselreaction
d Idiosyncraticlresponse
.
ACCURATElRESPONSE:-B
Reviewlfeedbackl:-
>>>Thelaimloflmedicalldrugltherapylisltoltakelalmedicalldrugltolprevent,llessen,lorlcorrectlalhealth
lproblem.lThislresponselislanylmedicalldrug’slintendedlactionlalsolknownlaslaltherapeuticlrespons
e.
DIFFICULT:lCognitivelLevel:lRemembering REF: p.l3
3. Whichltypeloflmedicalldruglnamelisl“owned”lbylthelcompanylthatlmanufactureslit?
a. Genericlname
b Chemicallname
.
c. Categorylname
d Tradelname
.
ACCURATElRESPONSE:-D
Reviewlfeedback:-
>>>Thelchemicallnamelislalmedicalldrug’slexactlchemicallcomposition.lThelgenericlnamelislthel
,namelassignedltolthelmedicalldruglbylthelU.S.lAdoptedlNameslCouncillandlislnotlownedlbylanyo
ne.lThelcategorylnamelrefersltoltheltypeloflmedicalldrugl(whatlitldoeslorlwhatlitlislusedlfor)landlisl
notlanlactuallmedicalldruglname.lTheltradelnamel(brandlname)lislthelnamelprovidedlandlownedlb
ylalspecificlmedicalldrug’slmanufacturer.
DIFFICULT:lCognitivelLevel:lRemembering REF: p.l4
4. Whichlmedicalldruglorlmedicalldruglclasslislal“highlalert”lmedicalldrug?
a. Penicillin
b Insulin
.
c. NSAIDs
d Calcium
.
ACCURATElRESPONSE:-B
Reviewlfeedback:-
>>>Alhighlalertlmedicalldruglislonelinlwhichlharmlisllikelyltolresultliflgivenlatlthelwrongldose,ltolt
helwronglhospitallclient,lorlnotlgivenltolthelcorrectlhospitallclient.lMedicalldrugslclassifiedlaslhighl
alertlmedicalldrugslincludelpotassium,lnarcoticsl(opioids),linsulin,lcancerlchemotherapylmedicalld
rugs,landlheparinl(orlanylmedicalldruglthatlstronglylaffectslbloodlclotting).lPenicillin,lNSAIDs,lan
dlcalciumlarelnotlconsideredlhighlalertlmedicalldrugs.
DIFFICULT:lCognitivelLevel:lRemembering REF: p.l4
5. Whatlisltheltermlforlalmedicalldruglthatlhaslthelsamelactionlaslalnaturallyloccurring
lbodylhormonelorlenzyme?
a. Agonist
b Blockinglagent
.
c. Chemical
d Duplicator
.
ACCURATElRESPONSE:-l A
Reviewlfeedback:-
>>>Almedicalldruglagonistlislanlextrinsiclmedicalldruglthatlactivateslthelreceptorlsitesloflalcelllan
dlmimicslthelactionsloflnaturallyloccurringlbodylsubstancesl(intrinsiclmedicalldrugs).lAlblockingl
agentlislalmedicalldruglantagonist.lAlchemicallwouldlnotlnecessarilylbelalmedicalldruglatlall.lAldup
licatorlislnotlalpharmacologiclterm.
DIFFICULT:lCognitivelLevel:lRemembering REF: pp.l6-7
6. Whichltermldescribeslhowlthelbodylaffectslmedicalldruglactivity?
a. Medicalldruglpoten
cy
b Pharmacodynamics
.
c. Therapeuticleffect
d Pharmacokinetics
.
, ACCURATElRESPONSE:-D
Reviewlfeedback:-
>>>Theltermlpharmacokineticslrefersltolmedicalldruglmetabolismlandlhowlthelbodylchangeslalm
edicalldrug.lPharmacodynamicslrefersltolhowlalmedicalldruglworksltolchangelbodylfunction.lMed
icalldruglpotencylrefersltolhowlstronglylorltolwhatldegreelalmedicalldruglexertslitsleffects.lThelthe
rapeuticleffectlislcloserltolpharmacodynamics,lmeaninglhowlalmedicalldruglworksltolchangelbod
ylfunction.
DIFFICULT:lCognitivelLevel:lRemembering REF: p.l10
7. InlthelUnitedlStates,lwhichlgrouplislresponsiblelforlenforcinglestablishedlstandardslforlm
edicalldruglmanufacturing?
a. U.S.lPharmacopeia
b NationallInstitutesloflHealth
.
c. FoodlandlMedicalldruglAdministration
d AssociationloflPharmaceuticallManufacturers
.
ACCURATElRESPONSE:-C
Reviewlfeedback:-
>>>ThelstandardslforlmedicalldruglmanufacturelarelestablishedlbylthelU.S.lPharmacopeia.lThese
lstandardslarelenforcedlbylthelFoodlandlMedicalldruglAdministration.lNeitherlthelNationallInstitu
tesloflHealthlnorlthelAssociationloflPharmaceuticallManufacturerslhaslanylauthorityltolenforcelm
edicalldruglstandards.
DIFFICULT:lCognitivelLevel:lRemembering REF: p.l5
8. Whichlfactorlislalmajorldisadvantagelofltheltransdermallmedicalldrugldeliverylroute?
a. Onlylalprescriberlcanladministerlmedicalldrugslbyltheltransdermal
lroute.
b Transdermallmedicalldrugslmustlbelsterilelratherlthanlclean.
.
c. Firstlpasslmedicalldrugllosslbylthislroutelislthelmostlextensive.
d Medicalldruglabsorptionlisldependentlonladequatelcirculation.
ACCURATElRESPONSE:-D
Reviewlfeedback:-
>>>Oncelaltransdermallmedicalldruglmoveslthroughlthelskin,litlmustlenterlthelbloodstreamltolreac
hlitsltargetltissue.lIflcirculationlislpoorltolthelarealwhereltheltransdermallmedicalldruglislapplied,lve
ryllittle,liflany,loflthelmedicalldruglwilllreachlitsltargetltissue.
DIFFICULT:lCognitivelLevel:lRemembering REF: p.l12
9. Howlarelintrinsiclmedicalldrugsldifferentl fromlextrinsiclmedicalldrugs?
a. Intrinsiclmedicalldrugslarelmadelbylthelbody,lwhereaslextrinsiclmedicalldrugslarelmadeloutsid
elthelbody.
b Intrinsiclmedicalldrugslareladministeredlbylthelparenterallroute,lwhereaslextrinsiclmedicalldru
. gslareladministeredlbylthelorallroute.