Elena Bablenis Haveles
Haveles: Applied Pharmacology for the Dental Hygienist, 6th Edition
Chapter 01: Information, Sources, Regulatory Agencies, Drug Legislation, and
Prescription Writing
Test Bank
MULTIPLE CHOICE
1. Knowledge of pharmacology aids the dental professional in:
a. Obtaining a patient’s health history
b. Administering drugs in the office
c. Handling emergency situations
d. Life-long learning
e. All of the above
ANS: e
Correct: Because many of our patients are being treated with drugs, knowledge of
pharmacology helps in understanding and interpreting patients’ responses to health history
APPLIED questions. Knowledge of the therapeutic and adverse effects of medications obviously helps
in their proper administration in the office. Emergency situations may be caused by drugs or
treated by drugs; thus knowledge of pharmacology is of great help, especially because a
PHARMACOLOGY
rapid response is sometimes required. A clear understanding of the concepts of drug action,
drug handling by the body, and drug interactions will allow the dental practitioner to make
proper judgments and grasp the concepts relevant to new drug therapies on the market.
Incorrect choices: All of the choices are true.
FOR THE REF: pp. 3-4
DENTAL HYGIENIST
2. Which of the following statements is true regarding planning appointments?
a. Whether or not patients are taking medication for systemic diseases is of little consequence
in the dental office.
b. Asthmatic patients should have dental appointments in the morning.
c. Diabetic patients usually have fewer problems with a morning appointment compared with
afternoon appointments.
Sixth Edition d. Both b and c are correct.
ANS: c
Correct: Diabetic patients usually have relatively fewer problems with a morning
appointment.
Incorrect choices: Asthmatic patients should have afternoon appointments. Patients taking
medication for systemic diseases may require special handling in the dental office.
REF: p. 3
MOSBY volve Copyright © 2011, 2007 Mosby, Inc., an affiliate of Elsevier. All rights reserved.
Copyrighted Material
,Test Bank 1-2 Test Bank 1-3
and is often a combination of capital letters and numbers, the letters representing an
3. Nutritional or herbal supplements: abbreviation of the company name.
a. Carry the U.S. Food and Drug Administration (FDA) approval for disease states REF: p. 4
b. Are not drugs
c. Can cause adverse effects 6. A drug’s generic name is selected by the:
d. Will not interact with other drugs the patient may be taking
a. Pharmaceutical company manufacturing it
ANS: c b. FDA
Correct: Nutritional or herbal supplements are quite capable of causing adverse effects. c. U.S. Adopted Name Council
Incorrect choices: The vast majority of nutritional or herbal supplements do not carry FDA d. Federal Patent Office
approval for treating disease states. These supplements are drugs and can cause adverse
effects and interact with different drugs. ANS: c
Correct: Each drug is assigned only one generic name (e.g., cola). It is selected by the U.S.
REF: p. 3 Adopted Name Council.
Incorrect choices: The generic name is not selected by the FDA or the Federal Patent Office.
4. A side effect is defined as: The pharmaceutical company manufacturing the drug clearly has an influence on the generic
name given their drug, but the final decision is not theirs.
a. An unpredictable response to drugs that acts on nontarget organs
b. An unpredictable response to drugs that acts on target organs REF: pp. 4, 6
c. A predictable response to drugs that acts on nontarget organs
d. A predictable response to drugs that acts on target organs 7. The trade name of a drug will appear:
e. An allergic response to a drug
a. In parentheses before the generic name
ANS: c b. In parentheses after the generic name
Correct: Side effects refer to predictable responses to drugs that act on nontarget organs. c. Before the generic name, which will appear in parentheses
Incorrect choices: Allergy refers to an allergic response to a drug. d. After the generic name, which will appear in parentheses
REF: p. 4 ANS: b
Correct: The trade name of a drug will appear in parentheses after the generic name.
5. Which type of drug name usually begins with a lower case letter? Incorrect choices: The pharmaceutical company discovering the drug gives the drug a trade
name. Newer drugs are usually known by their trade name. Old and traditional drugs are
a. Brand name often known by their generic name.
b. Code name
c. Generic name REF: p. 4
d. Trade name
8. Which of the following choices is the most common reference book in the dental office?
ANS: c
Correct: Before any drug is marketed, it is given a generic name that becomes the “official” a. United States Pharmacopeia-Drug Information (USP DI)
name of the drug. Each drug is assigned only one generic name selected by the U.S. Adopted b. Physicians’ Desk Reference (PDR)
Name Council, and the name is not capitalized. c. Mosby’s Dental Drug Reference
Incorrect choices: The brand name is equivalent to the trade name and is capitalized. d. Lexi-Comp’s Drug Information Handbook for Dentistry
Although the brand name is technically the name of the company marketing the product, this
term is often used interchangeably with the trade name. The code name is the initial term ANS: b
used within a pharmaceutical company to refer to a drug while it is undergoing investigation Correct: The PDR is the most common reference book in the dental office because of its
historically inexpensive price.
Copyright © 2011, 2007 Mosby, Inc., an affiliate of Elsevier. All rights reserved. Copyright © 2011, 2007 Mosby, Inc., an affiliate of Elsevier. All rights reserved.
,Test Bank 1-4 Test Bank 1-5
Incorrect choices: The USP DI provides the health professional with necessary information c. Drug Enforcement Administration (DEA)
regarding basic pharmacology and pharmacokinetics, dosing, adverse reactions, and drug d. United States Pharmacopeia (USP)
interactions. Mosby’s Dental Drug Reference provides access to information on drugs
commonly taken by patients. Lexi-Comp’s Drug Information Handbook for Dentistry ANS: c
contains concise lists of drug attributes and sections relevant to dentistry for each drug. Correct: The DEA regulates the manufacture and distribution of substances with abuse
potential. Hence prescriber DEA numbers must appear on prescriptions for controlled
REF: p. 5 substances.
Incorrect choices: The FDA does not have any special powers in regard to drugs of abuse.
9. How many years must pass after a drug patent expires before other drug companies can The FTC regulates commerce and advertising claims of foods, over-the-counter (OTC)
market the same compound as a generic drug? products, and cosmetics. The USP regulates the uniformity and purity of drugs.
a. 20 years REF: p. 7
b. 17 years
c. 7 years 12. Which federal regulatory body is part of the U.S. Department of Health and Human
d. 0 years Services (USHHS)?
ANS: d a. FDA
Correct: Once a drug patent expires, competing companies may immediately market the b. OTC
same compound in generic form. c. FTC
Incorrect choices: After 17 years, the patent of the original drug expires, and other companies d. DEA
can market the same compound under a generic name.
ANS: a
REF: p. 6 Correct: Of the legitimate agencies listed, only the FDA is part of USHHS.
Incorrect choices: OTC is a nonsense answer. The FTC is an independent agency that reports
10. Two drug formulations that produce similar concentrations in the blood and tissues after to the U.S. Congress on its actions. The DEA is a part of the Department of Justice.
drug administration are considered to be __________ equivalent.
REF: p. 7
a. Chemically
b. Biologically 13. Which federal regulatory body regulates the trade practices of drug companies and
c. Therapeutically prohibits false advertising of foods, nonprescription drugs, and cosmetics?
ANS: b a. FDA
Correct: Biologic equivalence refers to identical pharmacokinetic parameters of two drug b. FTC
formulations (bioequivalence, for short). c. DEA
Incorrect choices: Chemical equivalence indicates that two formulations of a drug meet the d. OBRA
chemical and physical standards established by the regulatory agencies. Therapeutic
equivalence means that two formulations produce the same therapeutic effects over the same ANS: b
duration. Correct: Consumers who refer to care labels on their clothes, product warranties, or stickers
showing the energy costs of home appliances are using information required by the FTC.
REF: p. 6 Businesses must be familiar with the laws requiring truthful advertising and prohibiting price
fixing. These laws are also administered by the FTC. When the FTC was created in 1914, its
11. The federal body that determines whether a drug is considered as a controlled substance purpose was to prevent unfair methods of competition in commerce. Over the years, the U.S.
and to which schedule it belongs is the: Congress has passed additional laws giving the agency greater authority to police
anticompetitive practices.
a. FDA
b. Federal Trade Commission (FTC)
Copyright © 2011, 2007 Mosby, Inc., an affiliate of Elsevier. All rights reserved. Copyright © 2011, 2007 Mosby, Inc., an affiliate of Elsevier. All rights reserved.
, Test Bank 1-6 Test Bank 1-7
Incorrect choices: The FDA grants approval so that drugs can be marketed in the United b. Safety and efficacy
States. Before a drug can be approved by the FDA, it must be determined to be both safe and c. Dosage
effective. The DEA regulates the manufacture and distribution of substances that have a d. Both a and b
potential for abuse. OBRA (Omnibus Budget Reconciliation Act) is not a regulatory body; it e. Both b and c
is an act that mandates that pharmacists must provide patient counseling.
ANS: e
REF: p. 7 Correct: Both safety and efficacy must be demonstrated during phase III of the clinical
evaluation of a new drug. Dosage is also determined during this phase. During phase III,
14. An investigational new drug application (INDA) is submitted: clinical evaluation takes place involving a large number of patients who have the condition
for which the drug is indicated.
a. Before preclinical trials Incorrect choices: The main purpose of phase II is to test a drug’s effectiveness.
b. Before phase I trials
c. After phase II trials REF: p. 7
d. Before phase III trials
17. Which of the following choices is a schedule II controlled substance?
ANS: b
Correct: An INDA must be filed with the FDA before a drug company can commence phase I a. Marijuana
clinical trials. b. Propranolol
Incorrect choices: Animal testing data must be accumulated from preclinical trials before c. Amphetamine
filing an INDA. Phase I is the first trial using patients, and phases II and III follow phase I. d. Dextropropoxyphene (Darvon)
An INDA must be filed before any testing in humans can commence.
ANS: c
REF: p. 7 Correct: Amphetamine, oxycodone, morphine, and secobarbital are all schedule II controlled
substances.
15. Phase I clinical trials involve all of the following except one. Which of the following Incorrect choices: Marijuana is schedule I. Propranolol is a nonscheduled prescription drug.
choices is the exception? Dextropropoxyphene is schedule IV.
a. Safe dose range REF: p. 8
b. Toxic effects of the drug
c. Metabolism 18. Controlled substances in schedule __________ require a written prescription with the
d. Therapeutic activity provider’s signature and do not permit refills.
ANS: d a. II, III, and IV
Correct: In phase I clinical trials, small and then increasing doses are administered to a b. II and III
limited number of healthy human volunteers, primarily to determine safety. This phase c. III and IV
determines the biologic effects, metabolism, safe dose range in humans, and toxic effects of d. II only
the drug. Assessment of therapeutic activity is not a goal of phase I trials. e. III only
Incorrect choices: Biologic effects, metabolism, safe dose range in humans, and toxic effects
of the drug are, in fact, goals of phase I clinical trials. ANS: d
Correct: Controlled substances in schedule II require a written prescription with the
REF: p. 7 provider’s signature and do not permit refills. Any prescription for schedule II drugs must be
written in pen or indelible ink or typed. A designee of the dentist, such as the dental
16. Which of the following choices is determined during a phase III clinical evaluation of a hygienist, may write the prescription, but the prescriber must personally sign the prescription
new drug? in ink and is responsible for what any designee has written.
Incorrect choices: Prescriptions for controlled substances in both schedule III and schedule
a. Effectiveness IV may be telephoned, and no more than five prescriptions in 6 months are permitted.
Copyright © 2011, 2007 Mosby, Inc., an affiliate of Elsevier. All rights reserved. Copyright © 2011, 2007 Mosby, Inc., an affiliate of Elsevier. All rights reserved.
Haveles: Applied Pharmacology for the Dental Hygienist, 6th Edition
Chapter 01: Information, Sources, Regulatory Agencies, Drug Legislation, and
Prescription Writing
Test Bank
MULTIPLE CHOICE
1. Knowledge of pharmacology aids the dental professional in:
a. Obtaining a patient’s health history
b. Administering drugs in the office
c. Handling emergency situations
d. Life-long learning
e. All of the above
ANS: e
Correct: Because many of our patients are being treated with drugs, knowledge of
pharmacology helps in understanding and interpreting patients’ responses to health history
APPLIED questions. Knowledge of the therapeutic and adverse effects of medications obviously helps
in their proper administration in the office. Emergency situations may be caused by drugs or
treated by drugs; thus knowledge of pharmacology is of great help, especially because a
PHARMACOLOGY
rapid response is sometimes required. A clear understanding of the concepts of drug action,
drug handling by the body, and drug interactions will allow the dental practitioner to make
proper judgments and grasp the concepts relevant to new drug therapies on the market.
Incorrect choices: All of the choices are true.
FOR THE REF: pp. 3-4
DENTAL HYGIENIST
2. Which of the following statements is true regarding planning appointments?
a. Whether or not patients are taking medication for systemic diseases is of little consequence
in the dental office.
b. Asthmatic patients should have dental appointments in the morning.
c. Diabetic patients usually have fewer problems with a morning appointment compared with
afternoon appointments.
Sixth Edition d. Both b and c are correct.
ANS: c
Correct: Diabetic patients usually have relatively fewer problems with a morning
appointment.
Incorrect choices: Asthmatic patients should have afternoon appointments. Patients taking
medication for systemic diseases may require special handling in the dental office.
REF: p. 3
MOSBY volve Copyright © 2011, 2007 Mosby, Inc., an affiliate of Elsevier. All rights reserved.
Copyrighted Material
,Test Bank 1-2 Test Bank 1-3
and is often a combination of capital letters and numbers, the letters representing an
3. Nutritional or herbal supplements: abbreviation of the company name.
a. Carry the U.S. Food and Drug Administration (FDA) approval for disease states REF: p. 4
b. Are not drugs
c. Can cause adverse effects 6. A drug’s generic name is selected by the:
d. Will not interact with other drugs the patient may be taking
a. Pharmaceutical company manufacturing it
ANS: c b. FDA
Correct: Nutritional or herbal supplements are quite capable of causing adverse effects. c. U.S. Adopted Name Council
Incorrect choices: The vast majority of nutritional or herbal supplements do not carry FDA d. Federal Patent Office
approval for treating disease states. These supplements are drugs and can cause adverse
effects and interact with different drugs. ANS: c
Correct: Each drug is assigned only one generic name (e.g., cola). It is selected by the U.S.
REF: p. 3 Adopted Name Council.
Incorrect choices: The generic name is not selected by the FDA or the Federal Patent Office.
4. A side effect is defined as: The pharmaceutical company manufacturing the drug clearly has an influence on the generic
name given their drug, but the final decision is not theirs.
a. An unpredictable response to drugs that acts on nontarget organs
b. An unpredictable response to drugs that acts on target organs REF: pp. 4, 6
c. A predictable response to drugs that acts on nontarget organs
d. A predictable response to drugs that acts on target organs 7. The trade name of a drug will appear:
e. An allergic response to a drug
a. In parentheses before the generic name
ANS: c b. In parentheses after the generic name
Correct: Side effects refer to predictable responses to drugs that act on nontarget organs. c. Before the generic name, which will appear in parentheses
Incorrect choices: Allergy refers to an allergic response to a drug. d. After the generic name, which will appear in parentheses
REF: p. 4 ANS: b
Correct: The trade name of a drug will appear in parentheses after the generic name.
5. Which type of drug name usually begins with a lower case letter? Incorrect choices: The pharmaceutical company discovering the drug gives the drug a trade
name. Newer drugs are usually known by their trade name. Old and traditional drugs are
a. Brand name often known by their generic name.
b. Code name
c. Generic name REF: p. 4
d. Trade name
8. Which of the following choices is the most common reference book in the dental office?
ANS: c
Correct: Before any drug is marketed, it is given a generic name that becomes the “official” a. United States Pharmacopeia-Drug Information (USP DI)
name of the drug. Each drug is assigned only one generic name selected by the U.S. Adopted b. Physicians’ Desk Reference (PDR)
Name Council, and the name is not capitalized. c. Mosby’s Dental Drug Reference
Incorrect choices: The brand name is equivalent to the trade name and is capitalized. d. Lexi-Comp’s Drug Information Handbook for Dentistry
Although the brand name is technically the name of the company marketing the product, this
term is often used interchangeably with the trade name. The code name is the initial term ANS: b
used within a pharmaceutical company to refer to a drug while it is undergoing investigation Correct: The PDR is the most common reference book in the dental office because of its
historically inexpensive price.
Copyright © 2011, 2007 Mosby, Inc., an affiliate of Elsevier. All rights reserved. Copyright © 2011, 2007 Mosby, Inc., an affiliate of Elsevier. All rights reserved.
,Test Bank 1-4 Test Bank 1-5
Incorrect choices: The USP DI provides the health professional with necessary information c. Drug Enforcement Administration (DEA)
regarding basic pharmacology and pharmacokinetics, dosing, adverse reactions, and drug d. United States Pharmacopeia (USP)
interactions. Mosby’s Dental Drug Reference provides access to information on drugs
commonly taken by patients. Lexi-Comp’s Drug Information Handbook for Dentistry ANS: c
contains concise lists of drug attributes and sections relevant to dentistry for each drug. Correct: The DEA regulates the manufacture and distribution of substances with abuse
potential. Hence prescriber DEA numbers must appear on prescriptions for controlled
REF: p. 5 substances.
Incorrect choices: The FDA does not have any special powers in regard to drugs of abuse.
9. How many years must pass after a drug patent expires before other drug companies can The FTC regulates commerce and advertising claims of foods, over-the-counter (OTC)
market the same compound as a generic drug? products, and cosmetics. The USP regulates the uniformity and purity of drugs.
a. 20 years REF: p. 7
b. 17 years
c. 7 years 12. Which federal regulatory body is part of the U.S. Department of Health and Human
d. 0 years Services (USHHS)?
ANS: d a. FDA
Correct: Once a drug patent expires, competing companies may immediately market the b. OTC
same compound in generic form. c. FTC
Incorrect choices: After 17 years, the patent of the original drug expires, and other companies d. DEA
can market the same compound under a generic name.
ANS: a
REF: p. 6 Correct: Of the legitimate agencies listed, only the FDA is part of USHHS.
Incorrect choices: OTC is a nonsense answer. The FTC is an independent agency that reports
10. Two drug formulations that produce similar concentrations in the blood and tissues after to the U.S. Congress on its actions. The DEA is a part of the Department of Justice.
drug administration are considered to be __________ equivalent.
REF: p. 7
a. Chemically
b. Biologically 13. Which federal regulatory body regulates the trade practices of drug companies and
c. Therapeutically prohibits false advertising of foods, nonprescription drugs, and cosmetics?
ANS: b a. FDA
Correct: Biologic equivalence refers to identical pharmacokinetic parameters of two drug b. FTC
formulations (bioequivalence, for short). c. DEA
Incorrect choices: Chemical equivalence indicates that two formulations of a drug meet the d. OBRA
chemical and physical standards established by the regulatory agencies. Therapeutic
equivalence means that two formulations produce the same therapeutic effects over the same ANS: b
duration. Correct: Consumers who refer to care labels on their clothes, product warranties, or stickers
showing the energy costs of home appliances are using information required by the FTC.
REF: p. 6 Businesses must be familiar with the laws requiring truthful advertising and prohibiting price
fixing. These laws are also administered by the FTC. When the FTC was created in 1914, its
11. The federal body that determines whether a drug is considered as a controlled substance purpose was to prevent unfair methods of competition in commerce. Over the years, the U.S.
and to which schedule it belongs is the: Congress has passed additional laws giving the agency greater authority to police
anticompetitive practices.
a. FDA
b. Federal Trade Commission (FTC)
Copyright © 2011, 2007 Mosby, Inc., an affiliate of Elsevier. All rights reserved. Copyright © 2011, 2007 Mosby, Inc., an affiliate of Elsevier. All rights reserved.
, Test Bank 1-6 Test Bank 1-7
Incorrect choices: The FDA grants approval so that drugs can be marketed in the United b. Safety and efficacy
States. Before a drug can be approved by the FDA, it must be determined to be both safe and c. Dosage
effective. The DEA regulates the manufacture and distribution of substances that have a d. Both a and b
potential for abuse. OBRA (Omnibus Budget Reconciliation Act) is not a regulatory body; it e. Both b and c
is an act that mandates that pharmacists must provide patient counseling.
ANS: e
REF: p. 7 Correct: Both safety and efficacy must be demonstrated during phase III of the clinical
evaluation of a new drug. Dosage is also determined during this phase. During phase III,
14. An investigational new drug application (INDA) is submitted: clinical evaluation takes place involving a large number of patients who have the condition
for which the drug is indicated.
a. Before preclinical trials Incorrect choices: The main purpose of phase II is to test a drug’s effectiveness.
b. Before phase I trials
c. After phase II trials REF: p. 7
d. Before phase III trials
17. Which of the following choices is a schedule II controlled substance?
ANS: b
Correct: An INDA must be filed with the FDA before a drug company can commence phase I a. Marijuana
clinical trials. b. Propranolol
Incorrect choices: Animal testing data must be accumulated from preclinical trials before c. Amphetamine
filing an INDA. Phase I is the first trial using patients, and phases II and III follow phase I. d. Dextropropoxyphene (Darvon)
An INDA must be filed before any testing in humans can commence.
ANS: c
REF: p. 7 Correct: Amphetamine, oxycodone, morphine, and secobarbital are all schedule II controlled
substances.
15. Phase I clinical trials involve all of the following except one. Which of the following Incorrect choices: Marijuana is schedule I. Propranolol is a nonscheduled prescription drug.
choices is the exception? Dextropropoxyphene is schedule IV.
a. Safe dose range REF: p. 8
b. Toxic effects of the drug
c. Metabolism 18. Controlled substances in schedule __________ require a written prescription with the
d. Therapeutic activity provider’s signature and do not permit refills.
ANS: d a. II, III, and IV
Correct: In phase I clinical trials, small and then increasing doses are administered to a b. II and III
limited number of healthy human volunteers, primarily to determine safety. This phase c. III and IV
determines the biologic effects, metabolism, safe dose range in humans, and toxic effects of d. II only
the drug. Assessment of therapeutic activity is not a goal of phase I trials. e. III only
Incorrect choices: Biologic effects, metabolism, safe dose range in humans, and toxic effects
of the drug are, in fact, goals of phase I clinical trials. ANS: d
Correct: Controlled substances in schedule II require a written prescription with the
REF: p. 7 provider’s signature and do not permit refills. Any prescription for schedule II drugs must be
written in pen or indelible ink or typed. A designee of the dentist, such as the dental
16. Which of the following choices is determined during a phase III clinical evaluation of a hygienist, may write the prescription, but the prescriber must personally sign the prescription
new drug? in ink and is responsible for what any designee has written.
Incorrect choices: Prescriptions for controlled substances in both schedule III and schedule
a. Effectiveness IV may be telephoned, and no more than five prescriptions in 6 months are permitted.
Copyright © 2011, 2007 Mosby, Inc., an affiliate of Elsevier. All rights reserved. Copyright © 2011, 2007 Mosby, Inc., an affiliate of Elsevier. All rights reserved.
