ONCC EXAM 2026 PREMIUM PRACTICE TEST
COMPLETE QUESTIONS AND CORRECT
ANSWERS
◉ which genetic disorder is a known risk factor for renal tumors?
a. wilms tumor-aniridia syndrome
b. down syndrome
c. li-fraumeni syndrome
d. neurofibromatosis. Answer: a. wilms tumor-aniridia syndrome
◉ which of the following is a hallmark of cancer?
a. self-sufficiency in growth signals
b. sensitivity to antigrowth signals
c. increased apoptosis
d. limited angiogenesis. Answer: a. self-sufficiency in growth signals
◉ patients with sickle cell disease under the age of 3 are at an
increased risk of early mortality because of low:
a. levels of hemoglobin F
b. baseline white blood cell count
c. rate of pain crisis
,d. rate of acute chest syndrome. Answer: a. levels of hemoglobin F
◉ a metaiodobenzylguanidine scan is useful in determining
metastatic disease for which pediatric cancer?
a. neuroblastoma
b. non-Hodgkin lymphoma
c. osteosarcoma
d. Langerhans cell histicytosis. Answer: a. neuroblastoma
◉ what is the most common clinical presentation in Von Wildebrand
disease?
a. mucocutaneous bleeding
b. petechiae
c. joint pain
d. subconjunctival hemorrhage. Answer: a. mucocutaneous bleeding
one of the most common presenting symptoms
◉ what is the most reliable test for diagnosing paroxysmal nocturnal
hemoglobinuria?
a. high resolution flow cytometry
b. acid ham test
,c. sucrose lysis test
d. haptoglobin level. Answer: a. high resolution flow cytometry
◉ a 3 year-old presents to the hospital after the mother found a
medium-sized mass on the patients abdomen. the patient's other
symptoms include a blood pressure of 139/88 mmHg and hematuria
found on urinalysis. the nurse suspects the patient might have which
underlying genetic condition?
a. beckwith-Wiedemann syndrome
b. Li-Fraumeni syndrome
c. neurofibromatosis type 1
d. down syndrome. Answer: a. beckwith-Wiedemann syndrome
renal tumors are associated with aniridia, hemihypertrophy or
genital or renal malformations, Beckwith-Wiedemann syndrome,
and other overgrowth syndromes
◉ which of the following sodium levels is indicative of late syndrome
of inappropriate antidiuretic hormone? serum sodium:
a. 120 mEq/L
b. 135 mEq/L
c. 130 mEq/L
d. 125 mEq/L. Answer: a. 120 mEq/L
, ◉ a patient with acute promyelocyctic leukemia presents with a
diffuse purpuric rash, platelet count 12,000/mm3, and prothombin
time of 56 seconds. Which of the following is the most appropriate
initial order?
a. transfuse fresh frozen plasma
b. administer lovenox
c. initiate heparin infusion
d. begin factor replacement. Answer: a. transfuse fresh frozen
plasma
pt has DIC, treatment begins with transfusing FFP
◉ a patient receiving intravenous pegasparaginase develops hives
on the chest. what should the nurse do first?
a. stop the infusion
b. complete a full body assessment
c. administer oral diphenhydramine
d. notify the ordering provider. Answer: a. stop the infusion
◉ a patient diagnosed with Hodgkin lymphoma is admitted to the
oncology floor with a WBC count >200,000/mm3 and SOB. The
nurse anticipates which of the following physician orders?
a. initiation of leukopheresis
b. administration of maintenance IV fluids with potassium chloride
COMPLETE QUESTIONS AND CORRECT
ANSWERS
◉ which genetic disorder is a known risk factor for renal tumors?
a. wilms tumor-aniridia syndrome
b. down syndrome
c. li-fraumeni syndrome
d. neurofibromatosis. Answer: a. wilms tumor-aniridia syndrome
◉ which of the following is a hallmark of cancer?
a. self-sufficiency in growth signals
b. sensitivity to antigrowth signals
c. increased apoptosis
d. limited angiogenesis. Answer: a. self-sufficiency in growth signals
◉ patients with sickle cell disease under the age of 3 are at an
increased risk of early mortality because of low:
a. levels of hemoglobin F
b. baseline white blood cell count
c. rate of pain crisis
,d. rate of acute chest syndrome. Answer: a. levels of hemoglobin F
◉ a metaiodobenzylguanidine scan is useful in determining
metastatic disease for which pediatric cancer?
a. neuroblastoma
b. non-Hodgkin lymphoma
c. osteosarcoma
d. Langerhans cell histicytosis. Answer: a. neuroblastoma
◉ what is the most common clinical presentation in Von Wildebrand
disease?
a. mucocutaneous bleeding
b. petechiae
c. joint pain
d. subconjunctival hemorrhage. Answer: a. mucocutaneous bleeding
one of the most common presenting symptoms
◉ what is the most reliable test for diagnosing paroxysmal nocturnal
hemoglobinuria?
a. high resolution flow cytometry
b. acid ham test
,c. sucrose lysis test
d. haptoglobin level. Answer: a. high resolution flow cytometry
◉ a 3 year-old presents to the hospital after the mother found a
medium-sized mass on the patients abdomen. the patient's other
symptoms include a blood pressure of 139/88 mmHg and hematuria
found on urinalysis. the nurse suspects the patient might have which
underlying genetic condition?
a. beckwith-Wiedemann syndrome
b. Li-Fraumeni syndrome
c. neurofibromatosis type 1
d. down syndrome. Answer: a. beckwith-Wiedemann syndrome
renal tumors are associated with aniridia, hemihypertrophy or
genital or renal malformations, Beckwith-Wiedemann syndrome,
and other overgrowth syndromes
◉ which of the following sodium levels is indicative of late syndrome
of inappropriate antidiuretic hormone? serum sodium:
a. 120 mEq/L
b. 135 mEq/L
c. 130 mEq/L
d. 125 mEq/L. Answer: a. 120 mEq/L
, ◉ a patient with acute promyelocyctic leukemia presents with a
diffuse purpuric rash, platelet count 12,000/mm3, and prothombin
time of 56 seconds. Which of the following is the most appropriate
initial order?
a. transfuse fresh frozen plasma
b. administer lovenox
c. initiate heparin infusion
d. begin factor replacement. Answer: a. transfuse fresh frozen
plasma
pt has DIC, treatment begins with transfusing FFP
◉ a patient receiving intravenous pegasparaginase develops hives
on the chest. what should the nurse do first?
a. stop the infusion
b. complete a full body assessment
c. administer oral diphenhydramine
d. notify the ordering provider. Answer: a. stop the infusion
◉ a patient diagnosed with Hodgkin lymphoma is admitted to the
oncology floor with a WBC count >200,000/mm3 and SOB. The
nurse anticipates which of the following physician orders?
a. initiation of leukopheresis
b. administration of maintenance IV fluids with potassium chloride
