Emergency Medicine EOR: Obstetrics and Gynecology EXAM
2026\NEWEST EXAM WITH COMPLETE QUESTIONS AND
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What is the first step in evaluating amenorrhea in a reproductive-age
female?
Rule out pregnancy with urine or serum β-hCG before any further workup
What are the two categories of amenorrhea and their definitions?
Primary: absence of menses by age 15 with secondary sex characteristics (or
age 13 without); Secondary: absence of menses for >3 months in
previously menstruating female
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What is the most common cause of secondary amenorrhea?
Pregnancy - always check β-hCG first
What lab panel is ordered after negative β-hCG in secondary
amenorrhea workup?
TSH, prolactin, FSH, LH; if virilization suspected add testosterone and DHEA-
S
How do you differentiate outflow tract obstruction from ovarian failure in
amenorrhea?
Progesterone challenge test: withdrawal bleed = anovulation (intact outflow
tract); no bleed = either outflow obstruction or ovarian failure; check FSH to
differentiate
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Elevated FSH + LH with low estrogen in amenorrhea indicates what diagnosis?
Primary ovarian insufficiency (hypergonadotropic hypogonadism);
FSH >40 mIU/mL is diagnostic
Low FSH + LH with low estrogen in amenorrhea indicates what
diagnosis?
Hypothalamic or pituitary dysfunction (hypogonadotropic hypogonadism);
causes include stress, extreme exercise, anorexia, or pituitary tumor
What are classic features of Asherman syndrome and how is it diagnosed?
Intrauterine adhesions (synechiae) after D&C or uterine surgery; no
withdrawal bleed on progesterone challenge; diagnosed by hysteroscopy
(gold standard)
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What is the pathognomonic finding of Kallmann syndrome causing
amenorrhea?
Hypogonadotropic hypogonadism + anosmia (absent sense of smell) due to
GnRH neuron migration failure
What are the diagnostic criteria for PCOS (Rotterdam criteria) and its
relationship to amenorrhea?
Two of three: oligo/anovulation, clinical/biochemical
hyperandrogenism, polycystic ovaries on ultrasound; most common
cause of secondary amenorrhea after pregnancy
What is Couvelaire uterus and in what condition does it occur?
Extravasation of blood into uterine myometrium causing a purple, woody
uterus; occurs in severe placental abruption; may require hysterectomy
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