2026/2027 | 150 QUESTIONS AND CORRECT ANSWERS |
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HESI Critical Care Nursing Final Examination
HESI Critical Care Nursing Final Examination
Core Domains: Cardiovascular Critical Care (Hemodynamic Monitoring - CVP, PAP, PCWP, CO, SVR; Shock States - Cardiogenic,
Hypovolemic, Distributive/Septic, Obstructive; Advanced Cardiac Life Support Algorithms; Dysrhythmia Interpretation and Management;
Acute Coronary Syndrome; Heart Failure; Cardiomyopathies; Cardiac Surgery Recovery; Intra-Aortic Balloon Pump; Ventricular Assist
Devices), Respiratory Critical Care (Mechanical Ventilation Modes - Volume Control, Pressure Control, SIMV, PSV; Ventilator Settings
and Adjustments; ABG Interpretation; ARDS; Pulmonary Embolism; Chest Tube Management; Weaning Parameters; Airway
Management; Sedation and Paralysis Protocols), Neurological Critical Care (ICP Monitoring and Management; Traumatic Brain Injury;
Stroke Management; Subarachnoid Hemorrhage; Seizure Management; Therapeutic Hypothermia; Brain Death Determination; Sedation
Scales - RASS, Glasgow Coma Scale), Renal Critical Care (Continuous Renal Replacement Therapy - CRRT, CVVH, CVVHD;
Hemodialysis; Acute Kidney Injury; Electrolyte Emergencies; Acid-Base Disorders; Fluid Resuscitation), Endocrine Critical Care
(Diabetic Ketoacidosis; Hyperosmolar Hyperglycemic State; Adrenal Crisis; Thyroid Storm; Myxedema Coma; SIADH; Diabetes
Insipidus), Hematologic Critical Care (Disseminated Intravascular Coagulation; Heparin-Induced Thrombocytopenia; Massive Transfusion
Protocols; Coagulopathy Management), Gastrointestinal Critical Care (GI Bleed Management; Acute Pancreatitis; Liver Failure; Portal
Hypertension; Paracentesis), Multisystem Critical Care (Sepsis and Septic Shock - Surviving Sepsis Guidelines; SIRS Criteria; qSOFA;
MODS; SIRS; Systemic Inflammatory Response Syndrome; Multiple Organ Dysfunction Syndrome; End-of-Life Care in Critical Care;
Palliative Care; Family Support; Ethical Dilemmas), and Critical Care Pharmacology (Vasoactive Infusions - Norepinephrine, Epinephrine,
Dobutamine, Dopamine, Vasopressin; Sedatives - Propofol, Dexmedetomidine, Midazolam; Analgesics - Fentanyl, Morphine,
Hydromorphone; Neuromuscular Blocking Agents; Antiarrhythmics; Antimicrobial Therapy; Inotropic Agents)
Graduate Nursing Focus | HESI-Aligned Format
TABLE OF CONTENTS
Domain 1: Cardiovascular Critical Care 3
Domain 2: Respiratory Critical Care 22
Domain 3: Neurological Critical Care 41
Domain 4: Renal Critical Care 57
Domain 5: Endocrine Critical Care 70
Domain 6: Hematologic Critical Care 82
Domain 7: Gastrointestinal Critical Care 92
Domain 8: Multisystem Critical Care 102
Domain 9: Critical Care Pharmacology 120
Exam Structure
HESI Critical Care Final Examination is commonly structured as follows:
, 150 total questions
Multiple-choice format (single-best-answer)
Alternate item formats: Select-All-That-Apply (SATA), Ordered Response, Hot Spot, Chart/Exhibit, Next-Generation NCLEX (NGN)
Bow-Tie and Trend items
Application-, analysis-, and clinical judgment–focused items
Integrated case-based scenarios requiring critical care decision-making
Questions aligned with current AACN standards, evidence-based practice, and HESI competencies
3-hour time limit
Comprehensive coverage of all critical care body systems and interventions
Introduction
This HESI CRITICAL CARE COMPLETE LATEST FINAL EXAM preparation resource for the 2026/2027 academic cycle reflects
Elsevier's HESI (Health Education Systems, Inc.) assessment standards for critical care nursing. Critical care nursing requires specialized
knowledge and skills to care for patients with life-threatening conditions requiring continuous monitoring and advanced interventions. The
final examination evaluates comprehensive understanding of cardiovascular, respiratory, neurological, renal, endocrine, hematologic,
gastrointestinal, and multisystem critical care concepts, along with hemodynamic monitoring, mechanical ventilation, vasoactive
medications, sedation protocols, and ethical considerations in the intensive care unit. Mastery of HESI Critical Care content is essential for
nursing students preparing for critical care rotations, graduate nurses entering intensive care units, and experienced nurses seeking to
validate their critical care knowledge.
Answer Format
All questions must be presented in bold text for clear distinction and readability.
All correct answers must be presented in bold and lime green, followed by clearly defined, clinically focused rationales in italic format that reinforce
critical care nursing principles, advanced hemodynamic concepts, and clinical judgment required for HESI Critical Care exam success.
Domain 1: Cardiovascular Critical Care (Questions 1-20)
Question 1:
A patient in the ICU has a pulmonary artery catheter. The nurse notes the following hemodynamic values: CVP 2 mmHg,
PAP 20/10 mmHg, PCWP 6 mmHg, CO 3.2 L/min, SVR 1800 dynes/sec/cm-5. What type of shock does this data suggest?
A) Cardiogenic shock
B) Hypovolemic shock
C) Distributive/septic shock
D) Obstructive shock
Correct Answer: B) Hypovolemic shock
Rationale: These values indicate hypovolemic shock: low CVP (<5 mmHg), low PCWP (<8 mmHg), low CO, and high SVR
(compensatory vasoconstriction). Cardiogenic shock would show elevated filling pressures. Septic shock would show low SVR.
Obstructive shock would show elevated CVP and PCWP.
,Question 2:
A patient with cardiogenic shock has the following values: PCWP 24 mmHg, CO 2.8 L/min, SVR 2200 dynes/sec/cm-5.
Which intervention is MOST appropriate?
A) Administer IV fluids bolus
B) Initiate inotropic support (dobutamine)
C) Administer vasopressors only
D) Place in Trendelenburg position
Correct Answer: B) Initiate inotropic support (dobutamine)
Rationale: Cardiogenic shock shows elevated PCWP (>18 mmHg), low CO, and high SVR. Inotropes (dobutamine, milrinone)
improve contractility and CO. Fluids would worsen pulmonary edema. Vasopressors alone increase afterload. Trendelenburg
increases intracranial pressure.
Question 3:
Which finding indicates proper intra-aortic balloon pump (IABP) timing?
A) Inflation at peak of systole
B) Inflation at dicrotic notch, deflation before systole
C) Deflation at dicrotic notch
D) Continuous inflation
Correct Answer: B) Inflation at dicrotic notch, deflation before systole
Rationale: IABP inflates at the dicrotic notch (beginning of diastole) to augment coronary perfusion and deflates before systole to
reduce afterload. Improper timing can decrease cardiac output or cause aortic valve damage.
Question 4:
A patient develops ventricular tachycardia with a pulse. The patient is stable. What is the FIRST intervention?
A) Immediate defibrillation
B) Administer amiodarone
C) Synchronized cardioversion
D) Administer adenosine
Correct Answer: B) Administer amiodarone
, Rationale: For stable VT with a pulse, antiarrhythmic medications (amiodarone, lidocaine) are first-line. Defibrillation is for
pulseless VT/VF. Synchronized cardioversion is for unstable VT. Adenosine is for SVT, not VT.
Question 5:
Which ECG finding indicates acute myocardial infarction requiring immediate intervention?
A) ST-segment depression
B) ST-segment elevation in contiguous leads
C) T-wave inversion
D) Prolonged QT interval
Correct Answer: B) ST-segment elevation in contiguous leads
Rationale: ST-segment elevation in contiguous leads indicates STEMI requiring immediate reperfusion (PCI or thrombolytics). ST
depression indicates NSTEMI/ischemia. T-wave inversion is nonspecific. Prolonged QT increases risk of torsades.
Question 6:
A patient with heart failure has a BNP of 1200 pg/mL. What does this indicate?
A) Normal cardiac function
B) Significant heart failure
C) Pulmonary embolism
D) Myocardial infarction
Correct Answer: B) Significant heart failure
Rationale: BNP >100 pg/mL suggests heart failure. BNP >400 pg/mL is highly suggestive. BNP 1200 pg/mL indicates significant
heart failure with ventricular stretch. BNP is released in response to ventricular volume and pressure overload.
Question 7:
Which finding suggests cardiac tamponade?
A) Widened pulse pressure
B) Beck's triad (hypotension, JVD, muffled heart sounds)
C) Bounding pulses
D) Increased urine output
Correct Answer: B) Beck's triad (hypotension, JVD, muffled heart sounds)