Forensic Toxicology EXAM 1 with
100% Correct Answers
drugs - ANS-any natural or synthetic substance used to produce physiological or
psychological effects
-makes up 75% of physical evidence found at crime scenes
The physiological need for a drug caused by - ANS-seek to avoid withdrawal sickness
significantly contributes to addiction
Common classes- drugs of abuse - ANS--opioids
-Hallucinogens
-depressants
-Stimulants
-Designer drugs
-Sports Performance Enhancers
Opioids - ANS--All natural & synthetic drugs whose effects mimic those of morphine-
MOR
-relieve pain by depressing CNS
-Heroin, Codeine, Morphine, Oxycodone, Fentanyl
Opioids are derived from - ANS-opium that is harvested from the poppy plant
Hallucinogens - ANS--Used causes marked changes in normal thought processes,
perceptions & moods
-Marijuana, LSD, Mushrooms
Marijuana - ANS--Cannabis plant contains the chemical tetrahydrocannabinol (THC)
which has the most psychoactive effects
-Does not cause physical dependency
Depressants - ANS-Drugs that < activity of the CNS
-Alcohol (ethanol)
-Huffing agent's (glue, aerosol gas)
-ecstasy
-Barbiturates
-Anti anxiety drugs (xanax)
, Ebers Papyrus - ANS-1st written expression records Egyptian medical knowledge &
practices from ~1550 B.C. & describes naturally occurring toxic substances & their
antidotes.
Arsenic (As) - ANS-natural chemical that has been used widely throughout history as a
favored instrument of suicide & homicide.
James Marsh Test - ANS--reaction of As- containing samples with H2 gas generated by
the reaction of zinc with strong acid like H2SO4
-When heated product arsine gas As2H3 is reduced to metallic arsenic
-Presence of shiny deposit known as arsenic mirror- is positive
LaFarge Affair - ANS--Marie cappell accused of poisoning husband Charles, outdated
test detected no As
-Orfila detected As using state of the art Marsh method
-Demonstrated newer methods of chemical analysis
Bocarme case - ANS--In 1843, Alfred Visart, the Count de Bocarmé, married Lydia
Fougnies and they poisoned Gustav with nicotine
-Stas developed method liquid-liquid extraction, nicotine was isolated into organic
solvents
Alexander Gettler - ANS-1st lab director, & his lab staff developed methods to detect
many substances like ethanol, methanol, cyanide, chloroform & carbon monoxide, &
provided interpretations of the results
sample handling - ANS-1st event, wwhich involves sample selection, ID, preservation &
transmittal to the lab.
who usually selects samples required for the initial analysis & any retest from among
any in the body - ANS-post-mortem toxicologist
Ante-morem labs analysis - ANS-often limited to blood, urine, saliva & hair
"Ideal" samples - ANS-easily analyzed, the results are accurate & their interpretation
provides the required information
Stage I:from time of event to when sample collected - ANS-drugs & chemicals may
undergo metabolism, synthesis, non-metabolic degradation or redistribution from one
anatomical site to another
Stage II: time between the collection & initial analysis of samples, usually form hr, days,
or weeks - ANS-drugs/chemicals may be altered due to continued metabolism,
synthesis, non-enzymatic degradation or redistribution within the sample
100% Correct Answers
drugs - ANS-any natural or synthetic substance used to produce physiological or
psychological effects
-makes up 75% of physical evidence found at crime scenes
The physiological need for a drug caused by - ANS-seek to avoid withdrawal sickness
significantly contributes to addiction
Common classes- drugs of abuse - ANS--opioids
-Hallucinogens
-depressants
-Stimulants
-Designer drugs
-Sports Performance Enhancers
Opioids - ANS--All natural & synthetic drugs whose effects mimic those of morphine-
MOR
-relieve pain by depressing CNS
-Heroin, Codeine, Morphine, Oxycodone, Fentanyl
Opioids are derived from - ANS-opium that is harvested from the poppy plant
Hallucinogens - ANS--Used causes marked changes in normal thought processes,
perceptions & moods
-Marijuana, LSD, Mushrooms
Marijuana - ANS--Cannabis plant contains the chemical tetrahydrocannabinol (THC)
which has the most psychoactive effects
-Does not cause physical dependency
Depressants - ANS-Drugs that < activity of the CNS
-Alcohol (ethanol)
-Huffing agent's (glue, aerosol gas)
-ecstasy
-Barbiturates
-Anti anxiety drugs (xanax)
, Ebers Papyrus - ANS-1st written expression records Egyptian medical knowledge &
practices from ~1550 B.C. & describes naturally occurring toxic substances & their
antidotes.
Arsenic (As) - ANS-natural chemical that has been used widely throughout history as a
favored instrument of suicide & homicide.
James Marsh Test - ANS--reaction of As- containing samples with H2 gas generated by
the reaction of zinc with strong acid like H2SO4
-When heated product arsine gas As2H3 is reduced to metallic arsenic
-Presence of shiny deposit known as arsenic mirror- is positive
LaFarge Affair - ANS--Marie cappell accused of poisoning husband Charles, outdated
test detected no As
-Orfila detected As using state of the art Marsh method
-Demonstrated newer methods of chemical analysis
Bocarme case - ANS--In 1843, Alfred Visart, the Count de Bocarmé, married Lydia
Fougnies and they poisoned Gustav with nicotine
-Stas developed method liquid-liquid extraction, nicotine was isolated into organic
solvents
Alexander Gettler - ANS-1st lab director, & his lab staff developed methods to detect
many substances like ethanol, methanol, cyanide, chloroform & carbon monoxide, &
provided interpretations of the results
sample handling - ANS-1st event, wwhich involves sample selection, ID, preservation &
transmittal to the lab.
who usually selects samples required for the initial analysis & any retest from among
any in the body - ANS-post-mortem toxicologist
Ante-morem labs analysis - ANS-often limited to blood, urine, saliva & hair
"Ideal" samples - ANS-easily analyzed, the results are accurate & their interpretation
provides the required information
Stage I:from time of event to when sample collected - ANS-drugs & chemicals may
undergo metabolism, synthesis, non-metabolic degradation or redistribution from one
anatomical site to another
Stage II: time between the collection & initial analysis of samples, usually form hr, days,
or weeks - ANS-drugs/chemicals may be altered due to continued metabolism,
synthesis, non-enzymatic degradation or redistribution within the sample
