New York Gastroenterologist Licensing Exam —
Practice Test Questions And Correct Answers
(Verified Answers) Plus Rationales 2025|2026 Q&A
| Instant Download Pdf
1. A 52-year-old man with chronic GERD has new dysphagia to solids. Next
best test?
A. Barium swallow
B. Upper endoscopy
C. Esophageal manometry
D. pH impedance testing
New dysphagia is an alarm symptom; EGD evaluates for stricture or
malignancy.
2. Barrett’s esophagus with low-grade dysplasia is confirmed twice. Preferred
management?
A. PPI alone and repeat EGD in 3 years
B. Endoscopic eradication therapy (RFA)
C. Esophagectomy
D. H2 blocker therapy
Guidelines favor ablation for confirmed LGD to reduce cancer risk.
3. Best initial test for achalasia suspicion on history/exam?
A. EGD
B. pH study
C. Barium esophagram
D. CT chest
Esophagram shows bird-beak and guides to manometry for confirmation.
4. Gold standard to diagnose achalasia subtype?
A. Barium esophagram
, B. EGD
C. High-resolution manometry
D. Scintigraphy
Manometry classifies types I–III per Chicago Classification.
5. H. pylori test of cure timing after quadruple therapy?
A. Immediately after antibiotics
B. 1 week after
C. ≥4 weeks after, off PPIs for ~2 weeks
D. 6 months after
Avoid false negatives from antibiotics/PPIs.
6. NSAID user develops gastric ulcer; H. pylori negative. Next step?
A. Stop PPI
B. Begin misoprostol only
C. Continue PPI and discontinue NSAID if possible
D. Test for celiac disease
NSAIDs cause ulcers; PPI promotes healing; stop culprit if feasible.
7. Zollinger–Ellison syndrome screening test?
A. Serum pepsinogen
B. Fasting gastrin with gastric pH
C. Secretin urine test
D. Chromogranin A alone
Hypergastrinemia with low gastric pH suggests gastrinoma.
8. Celiac disease best initial serology (on gluten diet, no IgA deficiency)?
A. Anti-gliadin IgG
B. tTG IgA
C. Endomysial IgG
D. Deamidated gliadin IgG alone
tTG IgA is first-line with high sensitivity/specificity.
9. Colon cancer screening: average-risk 45-year-old. Preferred option?
A. Start at 50
, B. Start now with colonoscopy every 10 years
C. Start at 60 with FIT
D. Only stool DNA every 10 years
USPSTF/ACS recommend starting at 45.
10. After a high-quality colonoscopy removing 1–2 small (<10 mm) tubular
adenomas, surveillance interval?
A. 1 year
B. 2 years
C. 7–10 years
D. 3 months
Low-risk adenomas → longer interval.
11. Ulcerative colitis (UC) extent to sigmoid only, in remission. Cancer
surveillance start?
A. Immediately at diagnosis
B. 8 years after symptom onset
C. Only if PSC develops
D. Never needed
Longstanding colitis warrants surveillance from year 8.
12. Primary sclerosing cholangitis (PSC) with UC: colon cancer surveillance
interval?
A. Every 5 years
B. Annually from PSC diagnosis
C. Every 3 years
D. None if asymptomatic
PSC increases CRC risk; annual colonoscopy recommended.
13. First-line induction for mild left-sided UC?
A. Systemic steroids
B. Topical mesalamine plus oral mesalamine
C. Cyclosporine
D. Infliximab immediately
5-ASA topical + oral is preferred for mild disease.
Practice Test Questions And Correct Answers
(Verified Answers) Plus Rationales 2025|2026 Q&A
| Instant Download Pdf
1. A 52-year-old man with chronic GERD has new dysphagia to solids. Next
best test?
A. Barium swallow
B. Upper endoscopy
C. Esophageal manometry
D. pH impedance testing
New dysphagia is an alarm symptom; EGD evaluates for stricture or
malignancy.
2. Barrett’s esophagus with low-grade dysplasia is confirmed twice. Preferred
management?
A. PPI alone and repeat EGD in 3 years
B. Endoscopic eradication therapy (RFA)
C. Esophagectomy
D. H2 blocker therapy
Guidelines favor ablation for confirmed LGD to reduce cancer risk.
3. Best initial test for achalasia suspicion on history/exam?
A. EGD
B. pH study
C. Barium esophagram
D. CT chest
Esophagram shows bird-beak and guides to manometry for confirmation.
4. Gold standard to diagnose achalasia subtype?
A. Barium esophagram
, B. EGD
C. High-resolution manometry
D. Scintigraphy
Manometry classifies types I–III per Chicago Classification.
5. H. pylori test of cure timing after quadruple therapy?
A. Immediately after antibiotics
B. 1 week after
C. ≥4 weeks after, off PPIs for ~2 weeks
D. 6 months after
Avoid false negatives from antibiotics/PPIs.
6. NSAID user develops gastric ulcer; H. pylori negative. Next step?
A. Stop PPI
B. Begin misoprostol only
C. Continue PPI and discontinue NSAID if possible
D. Test for celiac disease
NSAIDs cause ulcers; PPI promotes healing; stop culprit if feasible.
7. Zollinger–Ellison syndrome screening test?
A. Serum pepsinogen
B. Fasting gastrin with gastric pH
C. Secretin urine test
D. Chromogranin A alone
Hypergastrinemia with low gastric pH suggests gastrinoma.
8. Celiac disease best initial serology (on gluten diet, no IgA deficiency)?
A. Anti-gliadin IgG
B. tTG IgA
C. Endomysial IgG
D. Deamidated gliadin IgG alone
tTG IgA is first-line with high sensitivity/specificity.
9. Colon cancer screening: average-risk 45-year-old. Preferred option?
A. Start at 50
, B. Start now with colonoscopy every 10 years
C. Start at 60 with FIT
D. Only stool DNA every 10 years
USPSTF/ACS recommend starting at 45.
10. After a high-quality colonoscopy removing 1–2 small (<10 mm) tubular
adenomas, surveillance interval?
A. 1 year
B. 2 years
C. 7–10 years
D. 3 months
Low-risk adenomas → longer interval.
11. Ulcerative colitis (UC) extent to sigmoid only, in remission. Cancer
surveillance start?
A. Immediately at diagnosis
B. 8 years after symptom onset
C. Only if PSC develops
D. Never needed
Longstanding colitis warrants surveillance from year 8.
12. Primary sclerosing cholangitis (PSC) with UC: colon cancer surveillance
interval?
A. Every 5 years
B. Annually from PSC diagnosis
C. Every 3 years
D. None if asymptomatic
PSC increases CRC risk; annual colonoscopy recommended.
13. First-line induction for mild left-sided UC?
A. Systemic steroids
B. Topical mesalamine plus oral mesalamine
C. Cyclosporine
D. Infliximab immediately
5-ASA topical + oral is preferred for mild disease.
