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Oxygenation/Perfusion NCLEX 2026 – 200+ Exam Questions & Illustrated Answers – Chest Tubes, COPD, ABGs & Dysrhythmias

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This document contains 200+ comprehensive NCLEX-style exam questions and fully explained answers focused on oxygenation and perfusion for the 2026 nursing exam. It integrates respiratory and cardiovascular pathophysiology, emergency interventions, oxygen therapy, suctioning procedures, chest tube management, arterial blood gas interpretation, and cardiac dysrhythmia recognition. The structured multiple-choice format with detailed rationales and clinical application scenarios makes it ideal for mastering high-yield exam content. The material thoroughly covers chest tube emergency management (placing the tube in sterile saline if disconnected, water-seal fluctuation expectations), suctioning sequence steps, tracheostomy care, incentive spirometry education, oxygen delivery systems (nasal cannula, Venturi mask, oxygen tent), and safe oxygen administration practices including flow meter regulation and hypoxic drive considerations in COPD. Advanced respiratory concepts include diffusion, pulmonary function testing, bronchoscopy, thoracentesis, pneumothorax assessment, pulmonary embolism recognition, atelectasis risk factors, postural drainage techniques, and signs of acute respiratory distress syndrome. Cardiovascular content includes ECG interpretation (QRS complex meaning, sinus tachycardia, ventricular tachycardia), myocardial infarction complications, cardiogenic shock monitoring, pulse deficits, cardiac output interpretation, hypoxia manifestations, anemia-related oxygen transport impairment, and dysrhythmia prioritization. The guide also reviews infant and pediatric respiratory norms, newborn respiratory rates, nasal flaring in infants, and age-specific assessment findings. Clinical safety is emphasized throughout, including recognition of hypoxia (confusion, dyspnea, small pulse pressure), ABG nursing responsibilities, opioid respiratory depression monitoring (respiratory rate and depth), delegation boundaries for tracheostomy care, suction pressure limits (80–150 mm Hg), and maximum suction time (10–20 seconds). The inclusion of scenario-based prioritization questions strengthens critical thinking and real-world nursing judgment. This resource is particularly suitable for: ADN and BSN nursing students Practical Nursing (LPN/LVN) students Medical-Surgical nursing students NUR 111 and Adult Health students Pathophysiology students NCLEX-PN candidates NCLEX-RN candidates It is relevant for courses such as: Fundamentals of Nursing Adult Health I & II Medical-Surgical Nursing Pathophysiology Oxygenation and Perfusion NCLEX Preparation Keywords: Oxygenation Perfusion NCLEX 2026, Chest Tube Management Nursing, COPD Oxygen Therapy, Arterial Blood Gas Interpretation, Ventricular Tachycardia Recognition, Suctioning Procedure Steps, Incentive Spirometry Teaching, Pneumothorax Assessment, Pulmonary Embolism Symptoms, Hypoxia Signs and Symptoms, Venturi Mask Oxygen, Nasal Cannula Flow Rate, Postural Drainage Positions, Cardiogenic Shock Monitoring, Pulse Oximetry Interpretation, Tracheostomy Care Nursing, Diffusion in Alveoli, Pediatric Respiratory Rates

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Oxygenation/Perfusion NCLEX
Questions 2026 Exam All
Answers and Illustrations Given



The nurse is caring for a male client with a chest tube. If the chest drainage

system is accidentally disconnected, what should the nurse plan to do?

A. Place the end of the chest tube in a container of sterile saline

B. Apply an occlusive dressing and notify the physician.

C. Clamp the chest tube immediately

,D. Secure the chest tube with tape - 🧠 ANSWER ✔✔A. Place the end of the

chest tube in a container of sterile saline

For a male client with chronic obstructive pulmonary disease, which nursing

intervention would help maintain a patent airway?

A. Restricting fluid intake to 1,000 ml/day

B. Enforcing absolute bed rest

C. Teaching the client how to perform controlled coughing

D. Administering prescribed sedatives regularly and in large amounts - 🧠

ANSWER ✔✔C. Teaching the client how to perform controlled coughing


Which of the following is true concerning the physiology of the

cardiovascular system?




A. Stimulating the parasympathetic system would cause the heart rate to

go up.

B. When a person has heart muscle disease, the heart muscles stretch as

far as is necessary to maintain function.

,C. The QRS interval on the electrocardiogram represents the electrical

impulses passing through the ventricles.

D. When stroke volume decreases, there is a resultant decrease in heart

rate. - 🧠 ANSWER ✔✔C. The QRS interval on the electrocardiogram

represents the electrical impulses passing through the ventricles.

The client has emphysema from smoking. During a respiratory system

assessment the nurse anticipates finding:




A. Abnormal palpation signs in the upper thorax

B. Dull sounds on percussion

C. A depressed sternum on inspection


D. Moist breath sounds on auscultation - 🧠 ANSWER ✔✔B. Dull sounds on

percussion

A 64-year-old client is seen in the emergency room for palpitations and mild

shortness of breath. The ECG reveals a normal P wave, P-R interval, and

QRS complex with a regular rhythm and rate of 108. The nurse should

recognize this cardiac dysrhythmia as:



COPYRIGHT©PROFFKERRYMARTIN 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE.
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, A. Sinus dysrhythmia

B. Sinus tachycardia

C. Supraventricular tachycardia


D. Ventricular tachycardia - 🧠 ANSWER ✔✔B. Sinus tachycardia


A client recently fractured his spinal cord at the C-3 level and is at great risk

for developing pneumonia primarily because:




A. The resulting paralysis immobilizes him, and secretions will increase in

his lungs

B. Innervation to the phrenic nerve is absent, preventing chest expansion

C. The resulting abnormal chest shape disallows efficient ventilatory

movement

D. Trauma decreases the ability of his red blood cells to carry oxygen - 🧠

ANSWER ✔✔B. Innervation to the phrenic nerve is absent, preventing

chest expansion

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