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  • Katholieke Universiteit Leuven (KU Leuven)
  • Psychologie
  • Menselijke biologie en ziekteleer
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VOLLEDIGE Samenvatting Menselijke biologie en ziekteleer (deel ziekteleer) | KU Leuven | 2024/25

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2024/2025 Written for academic year
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Katholieke Universiteit Leuven (KU Leuven)
Course
Menselijke biologie en ziekteleer
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Volledige samenvatting van het deel ziekteleer, bijhorend bij het vak "Menselijke biologie en ziekteleer" Geziene hoofdstukken: myocardial infarction - breastcancer - mucoviscidose & diabetes - inflammatoire darmziektes (IBD) - tubereuze sclerose en epilepsie

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ZIEKTELEER




Anouk Delaere
KULeuven


0

,INHOUD

INHOUD.................................................................................................................. 1
Myocardial infarction.............................................................................................. 2
Breastcancer.......................................................................................................... 7
Mucoviscidose & diabetes.................................................................................... 12
Inflammatoire darmziektes (IBD)..........................................................................15
Tubereuze sclerose (TSC) en epilepsie.................................................................17




1

, MYOCARDIAL INFARCTION

CASUS

 Vrouw van 61, diabetes, BMI 29, secretaresse, sedentaire levensstijl
 Laatste 2 jaar: verschillende episodes van vage pijn thv borstkas borst
voor 1 – 5 minuten
 Tijdens het fietsen (matige inspanning): acute pijn aan borstkas en
linkerarm, blijvende pijn, kortademig, gevallen en reageert niet goed
 Ambulance: zuurstof toegediend en pijnstillers (morfine)
 Bij spoedafdeling: ECH: ST elevatie
 Diagnose: acute myocardial infarction (acuut hartinfarct)
 R / acute trombolyse tijdens katheterisatie  klonter proberen oplossen:
terug bevloeiing v.h. hart
 Alles goed gekomen, behandeling gestart met statines en aspirine voor
secundaire voorkomen



CARDIO-VASCULAR DISEASE

= groep van aandoeningen v.h. hart (coronair) en de bloedvaten
(cerebrovasculair)

 Coronary heart disease / coronary artery disease
 Cerebrovascular disease
 Peripheral arterial disease
 Rheumatic heart disease
 Congenital heart disease
 Deep vein thrombosis and pulmonary embolism

Verstopping v.d. doorbloeding  hartinfact / beroerte

Van alle sterftes van bloedvaatziektes zijn hersen-
en hartinfarcten het meest frequent

Bloedvat:

 Endotheel: bindweefsel  heel fragile
 Bindweefsel
 Spierweefsel
 Buitenste laag

Hartbloedvaten  spier en heeft veel
voedingsstoffen en zuurstof nodig

Normaal bloedvat vs. opstapeling afval
(cholesterolkristallen & vet) die opstapelen in die
fragile endotheel laag  onderbreekt de
bloedtoevoer


2

Table of contents

  1. 01 INHOUD 2
  2. 02 Myocardial infarction 3
    1. Casus 3
    2. Cardio-vascular disease 3
    3. Risk factor for atherosclerosis 4
  3. 03 Breastcancer 8
    1. Casus 8
    2. Kanker 8
    3. Oorzaken kanker 9
    4. borstkanker 9
  4. 04 Mucoviscidose & diabetes 13
    1. casus 13
    2. Cystic fibrosis (CF) 13
    3. Diabetes mellitus 15
    4. Terug naar CF patiënt 15
  5. 05 Inflammatoire darmziektes (IBD) 16
    1. Casus 16
    2. Inflammatie darm systeem = IBD 16
    3. Ulcerative colitis (UC) 17
    4. Crohn’s disease 17
  6. 06 Tubereuze sclerose (TSC) en epilepsie 18
    1. casus 18
    2. TSC 19
    3. Epilepsie in TSC 20
    4. Epilepsie 20

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