BIOCHEM BOOK TEST BANK
PROVIDED WITH
ANSWERS(100%A+)
Amino acid side chains capable of forming hydrogen bonds are usually located on the protein
____ and form hydrogen bonds primarily with the ____.
a. surface, water solvent
b. interior, water solvent
c. surface, other amino acid side chains
d. interior, other amino acid side chains
e. all are true - ANSWERsurface, water solvent
QUESTION ____ amino acids are almost never found in the interior of a protein, but the protein
surface may consist of ____ amino acids.
a. Nonpolar, both polar and nonpolar
b. Nonpolar, mostly nonpolar
c. Polar, both polar and nonpolar
d. Polar, only polar
,e. Polar, only nonpolar - ANSWERPolar, both polar and nonpolar
QUESTION Electrostatic interactions among amino acid residues on proteins may be damped
out by high concentrations of:
a. water.
b. organic solvents.
c. salts.
d. heat.
e. all of the above. - ANSWERsalts.
QUESTION An electrostatic interaction might occur within a protein between which of the
following amino acid pairs at typical physiological pH?
a. Ser/Asn
b. Asp/Glu
c. Arg/Cys
d. Lys/Asp
e. Val/Ile - ANSWERLys/Asp
QUESTION ____ between tightly packed amino acid side chains in the interior of the protein
are a major contribution to protein structure.
a. Hydrogen bonds
b. Electrostatic interactions
c. Covalent ester bonds
d. Van der Waals interactions
e. All are true - ANSWERVan der Waals interactions
, QUESTION A hydrophobic interaction might occur within a protein between which of the
following amino acid pairs?
a. Ser/Ile
b. Val/Leu
c. Tyr/Cys
d. Lys/Asn
e. His/Val - ANSWERVal/Leu
QUESTION All of the information necessary for folding the peptide chain into its "native"
structure is contained in the ____ of the peptide.
a. amino acid sequence
b. amino acid composition
c. configuration
d. amino acid side chain charges
e. all are true - ANSWERamino acid sequence
QUESTION Amino acid sequence is:
a. primary structure.
b. secondary structure.
c. tertiary structure.
d. quaternary structure.
e. regular structure. - ANSWERprimary structure.
QUESTION Secondary and higher orders of structure are determined by all EXCEPT:
, a. hydrophobic interactions.
b. ionic bonds.
c. van der Waals forces.
d. hydrogen bonds.
e. peptide bonds. - ANSWERpeptide bonds.
QUESTION If an aspartic acid residue were present in the interior of a globular protein, it
would most likely be _________.
a. deprotonated and thus negatively charged
b. tightly associated with the R-group of a lysine residue
c. react with a cysteine to form a thioester
d. react with a serine to form an ester
e. none of the above - ANSWERtightly associated with the R-group of a lysine residue
QUESTION Planarity of the peptide bond means that no rotation occurs about the _____ bond
while rotation is allowed about the____ and ____ bonds.
a. C(O)-N; Cα-Cβ; N-Cα
b. C(O)-N; Cα-C(O); N-Cα
c. Cα-C(O); C(O)-N; N-Cα
d. N-Cα; Cα-C(O); C(O)-N
e. none of the above - ANSWERC(O)-N; Cα-C(O); N-Cα
QUESTION A Ramachandran plot shows:
PROVIDED WITH
ANSWERS(100%A+)
Amino acid side chains capable of forming hydrogen bonds are usually located on the protein
____ and form hydrogen bonds primarily with the ____.
a. surface, water solvent
b. interior, water solvent
c. surface, other amino acid side chains
d. interior, other amino acid side chains
e. all are true - ANSWERsurface, water solvent
QUESTION ____ amino acids are almost never found in the interior of a protein, but the protein
surface may consist of ____ amino acids.
a. Nonpolar, both polar and nonpolar
b. Nonpolar, mostly nonpolar
c. Polar, both polar and nonpolar
d. Polar, only polar
,e. Polar, only nonpolar - ANSWERPolar, both polar and nonpolar
QUESTION Electrostatic interactions among amino acid residues on proteins may be damped
out by high concentrations of:
a. water.
b. organic solvents.
c. salts.
d. heat.
e. all of the above. - ANSWERsalts.
QUESTION An electrostatic interaction might occur within a protein between which of the
following amino acid pairs at typical physiological pH?
a. Ser/Asn
b. Asp/Glu
c. Arg/Cys
d. Lys/Asp
e. Val/Ile - ANSWERLys/Asp
QUESTION ____ between tightly packed amino acid side chains in the interior of the protein
are a major contribution to protein structure.
a. Hydrogen bonds
b. Electrostatic interactions
c. Covalent ester bonds
d. Van der Waals interactions
e. All are true - ANSWERVan der Waals interactions
, QUESTION A hydrophobic interaction might occur within a protein between which of the
following amino acid pairs?
a. Ser/Ile
b. Val/Leu
c. Tyr/Cys
d. Lys/Asn
e. His/Val - ANSWERVal/Leu
QUESTION All of the information necessary for folding the peptide chain into its "native"
structure is contained in the ____ of the peptide.
a. amino acid sequence
b. amino acid composition
c. configuration
d. amino acid side chain charges
e. all are true - ANSWERamino acid sequence
QUESTION Amino acid sequence is:
a. primary structure.
b. secondary structure.
c. tertiary structure.
d. quaternary structure.
e. regular structure. - ANSWERprimary structure.
QUESTION Secondary and higher orders of structure are determined by all EXCEPT:
, a. hydrophobic interactions.
b. ionic bonds.
c. van der Waals forces.
d. hydrogen bonds.
e. peptide bonds. - ANSWERpeptide bonds.
QUESTION If an aspartic acid residue were present in the interior of a globular protein, it
would most likely be _________.
a. deprotonated and thus negatively charged
b. tightly associated with the R-group of a lysine residue
c. react with a cysteine to form a thioester
d. react with a serine to form an ester
e. none of the above - ANSWERtightly associated with the R-group of a lysine residue
QUESTION Planarity of the peptide bond means that no rotation occurs about the _____ bond
while rotation is allowed about the____ and ____ bonds.
a. C(O)-N; Cα-Cβ; N-Cα
b. C(O)-N; Cα-C(O); N-Cα
c. Cα-C(O); C(O)-N; N-Cα
d. N-Cα; Cα-C(O); C(O)-N
e. none of the above - ANSWERC(O)-N; Cα-C(O); N-Cα
QUESTION A Ramachandran plot shows:
