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Critical Care HESI Exam Question Bank (PDF) – Complete High‑Acuity Nursing Prep with Answers & Detailed Rationales | Hemodynamics, Mechanical Ventilation, Shock, Cardiac, Neuro, Renal, Sepsis & Pharmacology

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This Critical Care HESI Exam Question Bank provides a comprehensive collection of professionally written, exam‑style questions specifically designed for HESI Critical Care, advanced med‑surg, ICU rotations, and high‑acuity nursing exams. Every question includes a clear, evidence‑based rationale, making this resource ideal for students, new‑grad ICU nurses, CCRN candidates, NP students, and instructors who need reliable, high‑yield practice. Includes multiple‑choice, SATA, prioritization, delegation, and case‑based clinical‑judgment questions aligned with modern HESI testing frameworks. What’s Inside (High‑Quality Questions + Rationales) Critical Care Topics Covered Hemodynamic monitoring (CVP, PAWP, SVR, CO/CI) Mechanical ventilation (modes, alarms, ABGs, troubleshooting) Shock: septic, cardiogenic, hypovolemic, obstructive Cardiac monitoring, dysrhythmias & emergency interventions Respiratory failure & oxygenation strategies Neurological emergencies (ICP, stroke, TBI, seizures) Renal failure, CRRT & fluid/electrolyte management Sepsis, SIRS, MODS & evidence‑based bundles Endocrine crises (DKA, HHS, adrenal crisis) Trauma, burns & emergency stabilization Sedation, analgesia, delirium & comfort management Critical‑care pharmacology (vasoactive drips, sedation, analgesics) Question Types Included HESI‑style multiple‑choice Select‑all‑that‑apply (SATA) Prioritization & delegation Case‑based ICU scenarios Clinical‑judgment questions with step‑by‑step reasoning Each question includes a fully explained rationale that teaches the concept, not just the answer. Why This Question Bank Converts High‑difficulty, realistic HESI‑style questions Fully explained rationales for deep understanding Clean, organized, exam‑ready formatting Perfect for HESI Critical Care, CCRN prep, ICU orientation, and NP programs Ideal for students, instructors, tutors & clinical educators

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Critical Care HESI Exam

ACCURATE AND VERIFIED FOR GUARANTEED PASS | LATEST UPDATE



A client with asthma receives a prescription for high blood pressure during a

clinic visit. Which prescription should the nurse anticipate the client to receive

that is least likely to exacerbate asthma?

A. Carteolol (Ocupress).

B. Propranolol hydrochloride (Inderal).

C. Pindolol (Visken).

D. Metoprolol tartrate (Lopressor)

- Answer: D. Metoprolol tartrate (Lopressor).

RATIONALE:

The best antihypertensive agent for clients with asthma is metoprolol (Lopressor) (C), a
beta2

blocking agent which is also cardio-selective and less likely to cause bronchoconstriction. Pindolol

(A) is a beta2 blocker that can cause bronchoconstriction and increase asthmatic symptoms.

Although carteolol (B) is a beta blocking agent and an effective antihypertensive agent used in

managing angina, it can increase a client's risk for bronchoconstriction due to its nonselective beta

blocker action. Propranolol (D) also blocks the beta2 receptors in the lungs, causing

bronchoconstriction, and is not indicated in clients with asthma and other obstructive pulmonary
disorders.



A male client who has been taking propranolol (Inderal) for 18 months tells the

nurse that the healthcare provider discontinued the medication because his blood

pressure has been normal for the past three months. Which instruction should the

nurse provide?

A. Obtain another antihypertensive prescription to avoid withdrawal symptoms.

B. Stop the medication and keep an accurate record of blood pressure

,C. Report any uncomfortable symptoms after stopping the medication.

D. Ask the healthcare provider about tapering the drug dose over the next week.

- Answer: D. Ask the healthcare provider about tapering the drug dose over the next week.

RATIONALE:

Although the healthcare provider discontinued the propranolol, measures to prevent
rebound

cardiac excitation, such as progressively reducing the dose over one to two weeks (C),
should be

recommended to prevent rebound tachycardia, hypertension, and ventricular
dysrhythmias.

Abrupt cessation (A and B) of the beta-blocking agent may precipitate tachycardia and
rebound

hypertension, so gradual weaning should be recommended. (D) is not indicated.



A client who is taking clonidine (Catapres, Duraclon) reports drowsiness. Which

additional assessment should the nurse make?

A. Has the client experienced constipation recently?

B. Did the client miss any doses of the medication?

C. How long has the client been taking the medication?

D. Does the client use any tobacco products?

- Answer: C. How long has the client been taking the medication?

RATIONALE:

Drowsiness can occur in the early weeks of treatment with clonidine and with continued
use

becomes less intense, so the length of time the client has been on the medication (A)
provides

information to direct additional instruction. (B, C, and D) are not relevant.



The nurse is preparing to administer atropine, an anticholinergic, to a client

who is scheduled for a cholecystectomy. The client asks the nurse to explain the

reason for the prescribed medication. What response is best for the nurse to

provide? A. Provide a more rapid induction of anesthesia.

B. Induce relaxation before induction of anesthesia.

,C. Decrease the risk of bradycardia during surgery.
D. Minimize the amount of analgesia needed postoperatively.

- Answer: C. Decrease the risk of bradycardia during surgery.

RATIONALE:

Atropine may be prescribed preoperatively to increase the automaticity of the sinoatrial node
and

prevent a dangerous reduction in heart rate (B) during surgical anesthesia. (A, C and D) do
not

address the therapeutic action of atropine use perioperatively.



An 80-year-old client is given morphine sulphate for postoperative pain. Which

concomitant medication should the nurse question that poses a potential

development of urinary retention in this geriatric client? A. Antacids.

B. Tricyclic antidepressants.

C. Nonsteroidal anti-inflammatory agents.

D. Insulin.

- Answer: B. Tricyclic antidepressants.

RATIONALE:

Drugs with anticholinergic properties, such as tricyclic antidepressants (C), can exacerbate
urinary

retention associated with opioids in the older client. Although tricyclic antidepressants
and

antihistamines with opioids can exacerbate urinary retention, the concurrent use of (A and B)
with

opioids do not. Nonsteroidal anti-inflammatory agents (D) can increase the risk for bleeding,
but

do not increase urinary retention with opioids (D).


A client with osteoarthritis is given a new prescription for a nonsteroidal anti-

inflammatory drug (NSAID). The client asks the nurse, "How is this medication

different from the acetaminophen I have been taking?" Which information about

the therapeutic action of NSAIDs should the nurse provide? A. Are less expensive.

B. Provide anti-inflammatory response.

C. Increase hepatotoxic side effects.

, D. Cause gastrointestinal bleeding.

- Answer: B. Provide anti-inflammatory response

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