ADVANCED PHARMACOLOGY
TESTABLE QUESTIONS WITH
CORRECT ANSWERS
Why are nitrate-free periods every 24 hours necessary for the patient on
nitroglycerin therapy? - ANSWER-To inhibit the development of tolerance
What does a low level of thyroid-stimulating hormone indicate? - ANSWER-
Hyperthroidism
What would be the best option to treat a newly diagnosed patient with a low TSH
level with? - ANSWER-Propanolol (Inderal)
Spironoaldactone (Aldactone) has what mechanism of action (MOA)? - ANSWER-
Aldosterone antagonist
Heparin exerts its therapeutic action by what? - ANSWER-Upregulating the
activity of one of the body's natural anticoagulant molecules, antithrombin III
What physiologic action happens when the offending drug is administered during
an anaphylactic reaction. - ANSWER-Mast cells liberate large doses of histamine.
, What are two systemic psoriasis medications? - ANSWER-Photo-therapy and
topical corticosteroids
What is the first choice of drug therapy for the majority of patients with
uncomplicated stage I hypertension? - ANSWER-Thiazide diuretics
What is the effect of cardiac glycosides? - ANSWER-Digitalis glycosides have a
negative chronotropic effect on the cardiac muscle cells.
Amenorrhea is the most common side effect of which birth control medication? -
ANSWER-Medroxyprogesterone (Depo-Provera)
What is an anti-hypertensive agent which competes with epinephrine for available
beta-receptor sites? - ANSWER-Atenolol (Tenormin)
What type of action does nitrates have on the body? - ANSWER-Reduction in
systemic venous tone.
What is the recommended level of low-density lipoprotein cholesterol (LDL) for
patients with known coronary artery disease? - ANSWER-100mg/dl or less.
What is the MOA of group IV anti-dysrhythmia drugs? - ANSWER-Depressing
phase 4 depolarization and lengthening phases 1 and 2 repolarization.
Which drug therapy should be used to lower the serum concentration of thyroid
hormones and re-establish eumetabolic state in a patient with Graves' disease? -
ANSWER-Anti-thyroid drugs.
TESTABLE QUESTIONS WITH
CORRECT ANSWERS
Why are nitrate-free periods every 24 hours necessary for the patient on
nitroglycerin therapy? - ANSWER-To inhibit the development of tolerance
What does a low level of thyroid-stimulating hormone indicate? - ANSWER-
Hyperthroidism
What would be the best option to treat a newly diagnosed patient with a low TSH
level with? - ANSWER-Propanolol (Inderal)
Spironoaldactone (Aldactone) has what mechanism of action (MOA)? - ANSWER-
Aldosterone antagonist
Heparin exerts its therapeutic action by what? - ANSWER-Upregulating the
activity of one of the body's natural anticoagulant molecules, antithrombin III
What physiologic action happens when the offending drug is administered during
an anaphylactic reaction. - ANSWER-Mast cells liberate large doses of histamine.
, What are two systemic psoriasis medications? - ANSWER-Photo-therapy and
topical corticosteroids
What is the first choice of drug therapy for the majority of patients with
uncomplicated stage I hypertension? - ANSWER-Thiazide diuretics
What is the effect of cardiac glycosides? - ANSWER-Digitalis glycosides have a
negative chronotropic effect on the cardiac muscle cells.
Amenorrhea is the most common side effect of which birth control medication? -
ANSWER-Medroxyprogesterone (Depo-Provera)
What is an anti-hypertensive agent which competes with epinephrine for available
beta-receptor sites? - ANSWER-Atenolol (Tenormin)
What type of action does nitrates have on the body? - ANSWER-Reduction in
systemic venous tone.
What is the recommended level of low-density lipoprotein cholesterol (LDL) for
patients with known coronary artery disease? - ANSWER-100mg/dl or less.
What is the MOA of group IV anti-dysrhythmia drugs? - ANSWER-Depressing
phase 4 depolarization and lengthening phases 1 and 2 repolarization.
Which drug therapy should be used to lower the serum concentration of thyroid
hormones and re-establish eumetabolic state in a patient with Graves' disease? -
ANSWER-Anti-thyroid drugs.
