Lehne's Pharmacology for Nursing Care -
Elsevier e-Book on VitalSource, 12th
Edition
by Jacqueline Rosenjack Burchum, DNSc,
FNP-BC, CNE and Laura D. Rosenthal, DNP,
RN, ACNP-BC, FAANP
TEST BANK
Nursing Pharmacology Test Bank
Lehne’s Pharmacology for Nursing Care, 12th Edition
Unit I: Introduction
Chapter 1 – Orientation to Pharmacology
(Exactly 20 MCQs – Fast-Revision Style)
,1. Which statement best defines pharmacology?
A. The study of disease processes
B. The study of how drugs are administered
C. The study of drugs and their interactions with living systems
D. The study of herbal therapies only
Correct Answer: C
Rationale: Pharmacology is the study of drugs and their
interactions with living organisms, including mechanisms and
effects.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch. 1
– Orientation to Pharmacology
2. Which term describes the study of what the body does to a
drug?
A. Pharmacodynamics
B. Pharmacokinetics
C. Therapeutics
D. Toxicology
Correct Answer: B
Rationale: Pharmacokinetics includes absorption, distribution,
metabolism, and excretion—how the body handles a drug.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch. 1
,3. Which process occurs primarily in the liver and converts
drugs into less active forms?
A. Absorption
B. Distribution
C. Metabolism
D. Excretion
Correct Answer: C
Rationale: Most drug metabolism occurs in the liver via
enzymatic processes that often inactivate drugs.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch. 1
4. A drug’s half-life is best defined as the time required for:
A. A drug to reach peak effect
B. The body to eliminate all drug
C. 50% of the drug to be eliminated
D. The drug to begin absorption
Correct Answer: C
Rationale: Half-life is the time required for plasma drug
concentration to decrease by 50%.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch. 1
5. Which concept refers to the maximum effect a drug can
produce?
A. Potency
B. Efficacy
, C. Affinity
D. Selectivity
Correct Answer: B
Rationale: Efficacy refers to the greatest effect a drug can
produce regardless of dose.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch. 1
6. A drug that binds to a receptor and produces a response is
called a:
A. Antagonist
B. Partial agonist
C. Agonist
D. Enzyme inhibitor
Correct Answer: C
Rationale: An agonist activates receptors and produces a
biological response.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch. 1
7. Which factor most directly affects drug distribution?
A. Gastric pH
B. Renal perfusion
C. Plasma protein binding
D. Liver enzyme induction
Correct Answer: C
Rationale: Drugs bound to plasma proteins cannot exert
Elsevier e-Book on VitalSource, 12th
Edition
by Jacqueline Rosenjack Burchum, DNSc,
FNP-BC, CNE and Laura D. Rosenthal, DNP,
RN, ACNP-BC, FAANP
TEST BANK
Nursing Pharmacology Test Bank
Lehne’s Pharmacology for Nursing Care, 12th Edition
Unit I: Introduction
Chapter 1 – Orientation to Pharmacology
(Exactly 20 MCQs – Fast-Revision Style)
,1. Which statement best defines pharmacology?
A. The study of disease processes
B. The study of how drugs are administered
C. The study of drugs and their interactions with living systems
D. The study of herbal therapies only
Correct Answer: C
Rationale: Pharmacology is the study of drugs and their
interactions with living organisms, including mechanisms and
effects.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch. 1
– Orientation to Pharmacology
2. Which term describes the study of what the body does to a
drug?
A. Pharmacodynamics
B. Pharmacokinetics
C. Therapeutics
D. Toxicology
Correct Answer: B
Rationale: Pharmacokinetics includes absorption, distribution,
metabolism, and excretion—how the body handles a drug.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch. 1
,3. Which process occurs primarily in the liver and converts
drugs into less active forms?
A. Absorption
B. Distribution
C. Metabolism
D. Excretion
Correct Answer: C
Rationale: Most drug metabolism occurs in the liver via
enzymatic processes that often inactivate drugs.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch. 1
4. A drug’s half-life is best defined as the time required for:
A. A drug to reach peak effect
B. The body to eliminate all drug
C. 50% of the drug to be eliminated
D. The drug to begin absorption
Correct Answer: C
Rationale: Half-life is the time required for plasma drug
concentration to decrease by 50%.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch. 1
5. Which concept refers to the maximum effect a drug can
produce?
A. Potency
B. Efficacy
, C. Affinity
D. Selectivity
Correct Answer: B
Rationale: Efficacy refers to the greatest effect a drug can
produce regardless of dose.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch. 1
6. A drug that binds to a receptor and produces a response is
called a:
A. Antagonist
B. Partial agonist
C. Agonist
D. Enzyme inhibitor
Correct Answer: C
Rationale: An agonist activates receptors and produces a
biological response.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch. 1
7. Which factor most directly affects drug distribution?
A. Gastric pH
B. Renal perfusion
C. Plasma protein binding
D. Liver enzyme induction
Correct Answer: C
Rationale: Drugs bound to plasma proteins cannot exert
