Ultra-High-Yield Comprehensive
Board Exam Mastery Review:
Immunology, Infectious Disease,
Cardiology, Neurology,
Pharmacology, Pathology, Genetics,
Endocrinology, Nephrology,
Oncology, Clinical Integration
Questions Complete with Verified A+
Graded Rationales Latest Updated
2026
5 bugs that cause heart block
Lyme Dz
Salmonella
Diptheria
Legionalla
Chagas
"LSD Loves Company"
What is IL-3 secreted by and what does it do
Secreted by T Cells
Labeled by Thymidine
It causes B cell proliferation
What is IL-4 secreted by and what does it do
Secreted by T cells
Causes B cell differentiation
Responsible for class switching to IgG and IgE
1|Page
,What is IL-5 secreted by and what does it do
Secreted by T cells
Responsible for class switching to IgA
What is IL-8 secreted by and what does it do
Neutrophil chemotactic factor
What is IL-10 secreted by and what does it do
Suppresses cell mediated response
Tells macrophages and T cells to stay away if there is a bacterial infection
What is IL-12 secreted by and what does it do
Promotes cell mediated response
If the infection is not bacterial, it is released to recruit macrophages and T cells
It activates NK cells to secrete IF-gamma
Inhibits IL-4 induced IgE secretions
Changes Th into Th1 cells
What is IF-alpha secreted by and what does it do
Secreted by Leukocytes
It inhibits viral replication and tumor growth
Increases NK activity
Increases MHC (I and II) expression
Interferes with protein synthesis
What is IF-beta secreted by and what does it do
Secreted by fibroblasts
It inhibits viral replication and tumor growth
Increases NK activity
Increases MHC (I and II) expression
Interferes with protein synthesis
What is IF-gamma secreted by and what does it do
Secreted by T cells and NK cells
2|Page
,It Increases NK activity
Increases MHC (I and II) expression
Increases macrophage activity
costimulates B cell growth and differentiation
Decreases IgE secretion
What is TNF-alpha secreted by and what does it do
What is it also known as
aka Cachectin
Secreted by monocytes and macrophages
It induces IL-1
Increases adhesion molecules and MHC I on endothelial cells
Induces secretion of IF-gamma
Is a pyogen
Is cytotoxic/cytostatic
What is TNF-beta secreted by and what does it do
What is it also known as
aka Lymphotoxin
Secreted by T cells
Is cytotoxic
What is TGF-alpha secreted by and what does it do
(Transforming Growth Factor)
Secreted by solid tumors (carcinoma < sarcoma) and monocytes
It induces angiogenesis
keratinocyte proliferation
bone resorption
tumor growth
3|Page
, What is TGF-beta secreted by and what does it do
(Transforming Growth Factor)
Secreted by platelets, placenta, kidney, bone, T and B cells
It induces fibroblast proliferation
collagen synthesis
fibronectin synthesis
Inhibits Lymphokine Activated Killer Cells
NKs
CTLs
T and B cell proliferation
Enhances wound healing and angiogenesis
What is IL-2 secreted by and what does it do
Secreted by T cells
Most powerful chemotactic factor (recruits everyone)
Must be inactivated prior to transplantation
What is IL-1 secreted by and what does it do
Secreted by macrophages
It recruits Thelper cells
Causes fever
Where is IgM found and what does it do
It is present only in the primary immune response
Defends against bacteria and viruses
Most effective in agglutination and complement fixation
Where is IgG found and what does it do
It is produced after IgM in the primary immune response
Only one produced during the 2nd immune response
It crosses the placenta
If you are deficient, you are susceptible to encapsulated organisms
4|Page
Board Exam Mastery Review:
Immunology, Infectious Disease,
Cardiology, Neurology,
Pharmacology, Pathology, Genetics,
Endocrinology, Nephrology,
Oncology, Clinical Integration
Questions Complete with Verified A+
Graded Rationales Latest Updated
2026
5 bugs that cause heart block
Lyme Dz
Salmonella
Diptheria
Legionalla
Chagas
"LSD Loves Company"
What is IL-3 secreted by and what does it do
Secreted by T Cells
Labeled by Thymidine
It causes B cell proliferation
What is IL-4 secreted by and what does it do
Secreted by T cells
Causes B cell differentiation
Responsible for class switching to IgG and IgE
1|Page
,What is IL-5 secreted by and what does it do
Secreted by T cells
Responsible for class switching to IgA
What is IL-8 secreted by and what does it do
Neutrophil chemotactic factor
What is IL-10 secreted by and what does it do
Suppresses cell mediated response
Tells macrophages and T cells to stay away if there is a bacterial infection
What is IL-12 secreted by and what does it do
Promotes cell mediated response
If the infection is not bacterial, it is released to recruit macrophages and T cells
It activates NK cells to secrete IF-gamma
Inhibits IL-4 induced IgE secretions
Changes Th into Th1 cells
What is IF-alpha secreted by and what does it do
Secreted by Leukocytes
It inhibits viral replication and tumor growth
Increases NK activity
Increases MHC (I and II) expression
Interferes with protein synthesis
What is IF-beta secreted by and what does it do
Secreted by fibroblasts
It inhibits viral replication and tumor growth
Increases NK activity
Increases MHC (I and II) expression
Interferes with protein synthesis
What is IF-gamma secreted by and what does it do
Secreted by T cells and NK cells
2|Page
,It Increases NK activity
Increases MHC (I and II) expression
Increases macrophage activity
costimulates B cell growth and differentiation
Decreases IgE secretion
What is TNF-alpha secreted by and what does it do
What is it also known as
aka Cachectin
Secreted by monocytes and macrophages
It induces IL-1
Increases adhesion molecules and MHC I on endothelial cells
Induces secretion of IF-gamma
Is a pyogen
Is cytotoxic/cytostatic
What is TNF-beta secreted by and what does it do
What is it also known as
aka Lymphotoxin
Secreted by T cells
Is cytotoxic
What is TGF-alpha secreted by and what does it do
(Transforming Growth Factor)
Secreted by solid tumors (carcinoma < sarcoma) and monocytes
It induces angiogenesis
keratinocyte proliferation
bone resorption
tumor growth
3|Page
, What is TGF-beta secreted by and what does it do
(Transforming Growth Factor)
Secreted by platelets, placenta, kidney, bone, T and B cells
It induces fibroblast proliferation
collagen synthesis
fibronectin synthesis
Inhibits Lymphokine Activated Killer Cells
NKs
CTLs
T and B cell proliferation
Enhances wound healing and angiogenesis
What is IL-2 secreted by and what does it do
Secreted by T cells
Most powerful chemotactic factor (recruits everyone)
Must be inactivated prior to transplantation
What is IL-1 secreted by and what does it do
Secreted by macrophages
It recruits Thelper cells
Causes fever
Where is IgM found and what does it do
It is present only in the primary immune response
Defends against bacteria and viruses
Most effective in agglutination and complement fixation
Where is IgG found and what does it do
It is produced after IgM in the primary immune response
Only one produced during the 2nd immune response
It crosses the placenta
If you are deficient, you are susceptible to encapsulated organisms
4|Page
