NUR 521 ADVANCED PHARMACOLOGY
EXAM 3 PRACTICE QUESTIONS AND
ANSWERS WITH RATIONALES 2025
UNIVERSITY OF ALABAMA TEST BANK
2026 UPDATED QUESTIONS AND ANSWERS
GRADED A+
⩥ specific acquired immunity. Answer: Immunity in which responses
occur only after exposure to a foreign substance. Objective is to destroy
antigens
⩥ Antigens. Answer: The foreign substances that induce specific
responses in specific acquired immunity
⩥ Cell-mediated, Humoral (antibody-mediated). Answer: the two classes
of specific acquired immunity
⩥ Cell-mediated immunity. Answer: refers to immune responses in
which targets are attacked directly by immune system cells—
specifically, cytolytic T cells and macrophages
⩥ Humoral immunity. Answer: refers to immune responses that are
mediated by antibodies.
,⩥ B lymphocytes. Answer: have the job of making antibodies. Hence
mediates humoral immunity. produced in the bone marrow.
⩥ Cytolytic T Cells. Answer: attack and kill target cells directly, mature
in the thymus
⩥ Helper T cells. Answer: contribute to the immune response in three
ways: (1) they have an essential role in antibody production by B cells;
(2) they release factors that promote type IV sensitivity reactions, also
known as delayed-type hypersensitivity (DTH); and (3) they participate
in the activation of cytolytic T cells.
Are the immune cell that HIV attacks
Mature in the thymus
⩥ Macrophages. Answer: Present in all organs and tissues, primary role
is phagocytosis, (1) they are required for activation of T cells (both
helper T cells and cytolytic T cells), (2) they are the final mediators of
DTH, and (3) they phagocytize cells that have been tagged with
antibodies
⩥ Dendritic Cells. Answer: perform the same antigen-presenting task as
do macrophages, but do not act as scavengers
,⩥ Mast cells. Answer: These cells mediate immediate hypersensitivity
reactions, derived from basophils, concentrated in the skin and other soft
tissues, release histamine, heparin, and other compounds that cause the
symptoms of immediate hypersensitivity
⩥ Basophils. Answer: These cells mediate immediate hypersensitivity
reactions, circulate in the blood, release histamine, heparin, and other
compounds that cause the symptoms of immediate hypersensitivity
⩥ Neutrophils. Answer: phagocytize bacteria and other foreign particles,
avidly devour cells that have been tagged with antibodies of the
immunoglobulin G (IgG) class, major contributors to inflammation
⩥ Eosinophils. Answer: attack and destroy foreign particles that have
been coated with antibodies of the IgE class. Their usual target is
helminths (parasitic worms). also contribute to tissue injury and
inflammation associated with immediate hypersensitivity reactions.
⩥ Antibodies. Answer: are a family of structurally related glycoproteins
that mediate humoral immunity. The most characteristic feature is their
ability to recognize and bind with specific antigens.
⩥ Immunoglobulins and globulins.. Answer: Alternative names for
antibodies are
, ⩥ B lymphocytes. Answer: all antibodies are produced by
⩥ IgA. Answer: located in mucous membranes of the GI tract and lungs
and in many secretions, serve as the first line of defense against
microbes entering the body via these routes, transferred to infants via
breastmilk (not absorbed in the GI tract, but does protect the infant from
microbes in the GI tract)
⩥ IgD. Answer: found only on the surface of mature B cells where it
serves as a receptor for antigen recognition (along with IgM)
⩥ IgE. Answer: bind to the surface of mast cells, stimulating the release
of histamine, heparin, and other mediators from the mast cell causing
symptoms of allergy (hives, hay fever), bind to parasitic worms,
eosinophils bind to the ig, releasing compounds that lyse the worm
⩥ IgG. Answer: Produced in copious amounts in response to antigenic
stimulation, major antibody in blood, promote target-cell lysis, binds
target cells enhancing phagocytosis, transferred across the placenta to
fetal circulation providing neonatal immunity
⩥ IgM. Answer: first class of antibody produced in response to an
antigen, promotes target cell lysis, present on the surface of mature B
cells where it serves as a receptor for antigen recognition along with IgD
EXAM 3 PRACTICE QUESTIONS AND
ANSWERS WITH RATIONALES 2025
UNIVERSITY OF ALABAMA TEST BANK
2026 UPDATED QUESTIONS AND ANSWERS
GRADED A+
⩥ specific acquired immunity. Answer: Immunity in which responses
occur only after exposure to a foreign substance. Objective is to destroy
antigens
⩥ Antigens. Answer: The foreign substances that induce specific
responses in specific acquired immunity
⩥ Cell-mediated, Humoral (antibody-mediated). Answer: the two classes
of specific acquired immunity
⩥ Cell-mediated immunity. Answer: refers to immune responses in
which targets are attacked directly by immune system cells—
specifically, cytolytic T cells and macrophages
⩥ Humoral immunity. Answer: refers to immune responses that are
mediated by antibodies.
,⩥ B lymphocytes. Answer: have the job of making antibodies. Hence
mediates humoral immunity. produced in the bone marrow.
⩥ Cytolytic T Cells. Answer: attack and kill target cells directly, mature
in the thymus
⩥ Helper T cells. Answer: contribute to the immune response in three
ways: (1) they have an essential role in antibody production by B cells;
(2) they release factors that promote type IV sensitivity reactions, also
known as delayed-type hypersensitivity (DTH); and (3) they participate
in the activation of cytolytic T cells.
Are the immune cell that HIV attacks
Mature in the thymus
⩥ Macrophages. Answer: Present in all organs and tissues, primary role
is phagocytosis, (1) they are required for activation of T cells (both
helper T cells and cytolytic T cells), (2) they are the final mediators of
DTH, and (3) they phagocytize cells that have been tagged with
antibodies
⩥ Dendritic Cells. Answer: perform the same antigen-presenting task as
do macrophages, but do not act as scavengers
,⩥ Mast cells. Answer: These cells mediate immediate hypersensitivity
reactions, derived from basophils, concentrated in the skin and other soft
tissues, release histamine, heparin, and other compounds that cause the
symptoms of immediate hypersensitivity
⩥ Basophils. Answer: These cells mediate immediate hypersensitivity
reactions, circulate in the blood, release histamine, heparin, and other
compounds that cause the symptoms of immediate hypersensitivity
⩥ Neutrophils. Answer: phagocytize bacteria and other foreign particles,
avidly devour cells that have been tagged with antibodies of the
immunoglobulin G (IgG) class, major contributors to inflammation
⩥ Eosinophils. Answer: attack and destroy foreign particles that have
been coated with antibodies of the IgE class. Their usual target is
helminths (parasitic worms). also contribute to tissue injury and
inflammation associated with immediate hypersensitivity reactions.
⩥ Antibodies. Answer: are a family of structurally related glycoproteins
that mediate humoral immunity. The most characteristic feature is their
ability to recognize and bind with specific antigens.
⩥ Immunoglobulins and globulins.. Answer: Alternative names for
antibodies are
, ⩥ B lymphocytes. Answer: all antibodies are produced by
⩥ IgA. Answer: located in mucous membranes of the GI tract and lungs
and in many secretions, serve as the first line of defense against
microbes entering the body via these routes, transferred to infants via
breastmilk (not absorbed in the GI tract, but does protect the infant from
microbes in the GI tract)
⩥ IgD. Answer: found only on the surface of mature B cells where it
serves as a receptor for antigen recognition (along with IgM)
⩥ IgE. Answer: bind to the surface of mast cells, stimulating the release
of histamine, heparin, and other mediators from the mast cell causing
symptoms of allergy (hives, hay fever), bind to parasitic worms,
eosinophils bind to the ig, releasing compounds that lyse the worm
⩥ IgG. Answer: Produced in copious amounts in response to antigenic
stimulation, major antibody in blood, promote target-cell lysis, binds
target cells enhancing phagocytosis, transferred across the placenta to
fetal circulation providing neonatal immunity
⩥ IgM. Answer: first class of antibody produced in response to an
antigen, promotes target cell lysis, present on the surface of mature B
cells where it serves as a receptor for antigen recognition along with IgD